Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF843 Gene

Aliases for ZNF843 Gene

  • Zinc Finger Protein 843 2 3 3 5

External Ids for ZNF843 Gene

Previous GeneCards Identifiers for ZNF843 Gene

  • GC16M031355
  • GC16M029007

Summaries for ZNF843 Gene

GeneCards Summary for ZNF843 Gene

ZNF843 (Zinc Finger Protein 843) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding.

Additional gene information for ZNF843 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF843 Gene

Genomics for ZNF843 Gene

GeneHancer (GH) Regulatory Elements for ZNF843 Gene

Promoters and enhancers for ZNF843 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J031441 Promoter/Enhancer 1.7 Ensembl ENCODE dbSUPER 650.7 +0.3 348 1.8 HDGF ARID4B SIN3A DMAP1 ZNF2 IRF4 YY1 POLR2B ZNF143 KLF13 ZNF843 ENSG00000260740 KAT8 LOC647086 SETD1A RNF40 ENSG00000261474 ZNF720 SRCAP ZNF747
GH16J031456 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 10.8 -15.7 -15669 4.9 CLOCK MLX ZFP64 DMAP1 IRF4 YY1 SLC30A9 E2F8 ZNF143 SP3 ARMC5 ENSG00000260267 GC16M031449 GC16M031458 PIR46378 SETD1A FUS SRCAP ZNF720 ZNF785
GH16J031451 Enhancer 1.4 Ensembl ENCODE dbSUPER 12.9 -10.7 -10702 4.7 HDGF PKNOX1 CLOCK ARNT ARID4B SIN3A DMAP1 ZNF2 ZNF143 FOS ENSG00000261474 ENSG00000260740 ENSG00000260267 ENSG00000260304 ZNF843 FBRS LOC647086 LOC730183 ZNF646 ZNF688
GH16J031427 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE dbSUPER 6.9 +13.8 13751 4.5 ZNF639 MEIS2 USF1 L3MBTL2 ZNF740 RNF2 NRF1 MAX MNT ZNF592 COX6A2 ENSG00000277543 ENSG00000260740 ARMC5 PYDC1 PRSS8 PYCARD PRSS36 FUS ZNF646
GH16J031484 Enhancer 1.1 Ensembl ENCODE 6.3 -41.7 -41651 1.7 ELF3 MLX ZSCAN4 ARID4B DMAP1 RAD21 RARA ZNF614 THAP11 MIXL1 ENSG00000260740 ZNF843 ITGAD SLC5A2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF843 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF843 gene promoter:
  • HNF-4alpha2
  • HNF-4alpha1
  • COUP-TF1
  • COUP-TF
  • COUP
  • Sp1
  • GR-beta
  • GR
  • GR-alpha
  • STAT5B

Genomic Locations for ZNF843 Gene

Genomic Locations for ZNF843 Gene
chr16:31,432,593-31,443,160
(GRCh38/hg38)
Size:
10,568 bases
Orientation:
Minus strand
chr16:31,445,569-31,454,348
(GRCh37/hg19)
Size:
8,780 bases
Orientation:
Minus strand

Genomic View for ZNF843 Gene

Genes around ZNF843 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF843 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF843 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF843 Gene

Proteins for ZNF843 Gene

  • Protein details for ZNF843 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N446-ZN843_HUMAN
    Recommended name:
    Zinc finger protein 843
    Protein Accession:
    Q8N446
    Secondary Accessions:
    • A8K4U8

    Protein attributes for ZNF843 Gene

    Size:
    348 amino acids
    Molecular mass:
    37065 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF843 Gene

Post-translational modifications for ZNF843 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF843 Gene

No data available for DME Specific Peptides for ZNF843 Gene

Domains & Families for ZNF843 Gene

Gene Families for ZNF843 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF843 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF843 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZNF843: view

No data available for UniProtKB/Swiss-Prot for ZNF843 Gene

Function for ZNF843 Gene

Gene Ontology (GO) - Molecular Function for ZNF843 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0005515 protein binding IPI 22939624
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF843: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF843

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF843 Gene

Localization for ZNF843 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF843 gene
Compartment Confidence
nucleus 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ZNF843 Gene

Pathways & Interactions for ZNF843 Gene

SuperPathways for ZNF843 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF843 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZNF843 Gene

Drugs & Compounds for ZNF843 Gene

No Compound Related Data Available

Transcripts for ZNF843 Gene

mRNA/cDNA for ZNF843 Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(246) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF843 Gene

Zinc finger protein 843:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF843

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF843 Gene

No ASD Table

Relevant External Links for ZNF843 Gene

GeneLoc Exon Structure for
ZNF843
ECgene alternative splicing isoforms for
ZNF843

Expression for ZNF843 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF843 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of ZNF843 Gene:

ZNF843

SOURCE GeneReport for Unigene cluster for ZNF843 Gene:

Hs.722243
genes like me logo Genes that share expression patterns with ZNF843: view

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF843 Gene

Orthologs for ZNF843 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ZNF843 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF843 33
  • 99.23 (n)
Species where no ortholog for ZNF843 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF843 Gene

ENSEMBL:
Gene Tree for ZNF843 (if available)
TreeFam:
Gene Tree for ZNF843 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF843: view image

Paralogs for ZNF843 Gene

(22) SIMAP similar genes for ZNF843 Gene using alignment to 2 proteins:

  • ZN843_HUMAN
  • H3BQN5_HUMAN
genes like me logo Genes that share paralogs with ZNF843: view

No data available for Paralogs for ZNF843 Gene

Variants for ZNF843 Gene

Sequence variations from dbSNP and Humsavar for ZNF843 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000047593 -- 31,435,348(-) G/A/T downstream_transcript_variant
rs1000665144 -- 31,442,896(-) G/A 5_prime_UTR_variant
rs1000682370 -- 31,435,950(-) C/A/G/T coding_sequence_variant, synonymous_variant
rs1000905548 -- 31,442,635(-) C/G splice_donor_variant
rs1001087595 -- 31,441,552(-) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF843 Gene

Variant ID Type Subtype PubMed ID
nsv1066280 CNV gain 25217958
nsv833194 CNV loss 17160897

Variation tolerance for ZNF843 Gene

Gene Damage Index Score: 4.37; 63.47% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF843 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF843

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF843 Gene

Disorders for ZNF843 Gene

Additional Disease Information for ZNF843

No disorders were found for ZNF843 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF843 Gene

Publications for ZNF843 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  3. A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways. (PMID: 25036637) Taipale M … Lindquist S (Cell 2014) 3 58
  4. Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. (PMID: 22939624) Taipale M … Lindquist S (Cell 2012) 3 58
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 58

Products for ZNF843 Gene

Sources for ZNF843 Gene

Content
Loading form....