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Aliases for ZNF839 Gene

Aliases for ZNF839 Gene

  • Zinc Finger Protein 839 2 3 3 5
  • Renal Carcinoma Antigen NY-REN-50 3 4
  • C14orf131 3 4
  • Chromosome 14 Open Reading Frame 131 2

External Ids for ZNF839 Gene

Previous HGNC Symbols for ZNF839 Gene

  • C14orf131

Previous GeneCards Identifiers for ZNF839 Gene

  • GC14P101855
  • GC14P102786
  • GC14P082969
  • GC14P102318
  • GC14P102381
  • GC14P102452
  • GC14P102462
  • GC14P102634
  • GC14P102802
  • GC14P102980

Summaries for ZNF839 Gene

GeneCards Summary for ZNF839 Gene

ZNF839 (Zinc Finger Protein 839) is a Protein Coding gene. Among its related pathways are Gene Expression.

Additional gene information for ZNF839 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF839 Gene

Genomics for ZNF839 Gene

GeneHancer (GH) Regulatory Elements for ZNF839 Gene

Promoters and enhancers for ZNF839 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14J103103 Enhancer 1.5 Ensembl ENCODE dbSUPER 23.1 +787.5 787450 3 HDGF PKNOX1 FOXA2 ARNT ZFP64 ARID4B NEUROD1 SIN3A DMAP1 YBX1 XRCC3 WDR20 RCOR1 BAG5 CDC42BPB ZNF839 ENSG00000259444 ENSG00000269940 RPL23AP11 KLC1
GH14J102084 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 11.1 -230.4 -230446 4.7 SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B ZNF766 ZNF207 HSP90AA1 WDR20 RCOR1 ZNF839 ENSG00000258959 MOK PIR41764 GC14P103479
GH14J102522 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 15 +208.6 208617 6 MLX YBX1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC GLIS1 RCOR2 RCOR1 WDR20 TECPR2 MOK ANKRD9 ZNF839 RPL23AP11 CDC42BPB TRAF3 RNU6-244P
GH14J102315 Promoter/Enhancer 2 Ensembl ENCODE dbSUPER 11.4 +2.4 2414 7.7 MLX DMAP1 YY1 ZNF213 ZNF143 SP3 NFYC SSRP1 ZNF610 GLIS1 RCOR1 ENSG00000272444 WDR20 ENSG00000271780 CINP TECPR2 CDC42BPB ZNF839 DYNC1H1 ENSG00000258959
GH14J102361 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 8.8 +45.6 45580 2.6 PKNOX1 ATF1 SMAD1 ARID4B SIN3A FEZF1 DMAP1 IRF4 ZNF48 YY1 CINP TECPR2 RCOR1 WDR20 ZNF839
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF839 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF839 gene promoter:
  • c-Jun
  • ATF-2
  • deltaCREB
  • CREB
  • AP-1
  • p53
  • Sp1
  • Ik-3

Genomic Locations for ZNF839 Gene

Genomic Locations for ZNF839 Gene
25,798 bases
Plus strand
25,331 bases
Plus strand

Genomic View for ZNF839 Gene

Genes around ZNF839 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF839 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF839 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF839 Gene

Proteins for ZNF839 Gene

  • Protein details for ZNF839 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 839
    Protein Accession:
    Secondary Accessions:
    • B3KSD2
    • Q53FH5
    • Q6GPI5
    • Q86TU1
    • Q9BQ86
    • Q9NUU3

    Protein attributes for ZNF839 Gene

    811 amino acids
    Molecular mass:
    87484 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA92026.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAD62594.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF839 Gene


neXtProt entry for ZNF839 Gene

Post-translational modifications for ZNF839 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF839 Gene

Domains & Families for ZNF839 Gene

Gene Families for ZNF839 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF839 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZNF839: view

No data available for UniProtKB/Swiss-Prot for ZNF839 Gene

Function for ZNF839 Gene

Phenotypes From GWAS Catalog for ZNF839 Gene

Gene Ontology (GO) - Molecular Function for ZNF839 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF839: view
genes like me logo Genes that share phenotypes with ZNF839: view

Animal Model Products

miRNA for ZNF839 Gene

miRTarBase miRNAs that target ZNF839

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF839 Gene

Localization for ZNF839 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF839 gene
Compartment Confidence
nucleus 4
plasma membrane 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (2)
  • Plasma membrane (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZNF839 Gene

Pathways & Interactions for ZNF839 Gene

SuperPathways for ZNF839 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF839: view

Pathways by source for ZNF839 Gene

2 Reactome pathways for ZNF839 Gene

Interacting Proteins for ZNF839 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: A8K0R7-ZN839_HUMAN ENSP00000399863 for ZNF839 Gene via IID STRING

Gene Ontology (GO) - Biological Process for ZNF839 Gene


No data available for SIGNOR curated interactions for ZNF839 Gene

Drugs & Compounds for ZNF839 Gene

No Compound Related Data Available

Transcripts for ZNF839 Gene

Unigene Clusters for ZNF839 Gene

Zinc finger protein 839:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF839 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11
SP1: - - - -
SP2: - -
SP3: - - - -
SP4: -
SP5: -
SP6: - -
SP7: -

Relevant External Links for ZNF839 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF839 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF839 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF839 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF839 Gene:


SOURCE GeneReport for Unigene cluster for ZNF839 Gene:


Evidence on tissue expression from TISSUES for ZNF839 Gene

  • Nervous system(4.2)
  • Lung(4.1)
genes like me logo Genes that share expression patterns with ZNF839: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF839 Gene

Orthologs for ZNF839 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF839 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF839 34 33
  • 98.4 (n)
(Canis familiaris)
Mammalia ZNF839 34 33
  • 76.18 (n)
(Rattus norvegicus)
Mammalia Zfp839 33
  • 67.8 (n)
(Mus musculus)
Mammalia Zfp839 16 34 33
  • 67.29 (n)
(Bos Taurus)
Mammalia ZNF839 34
  • 61 (a)
(Monodelphis domestica)
Mammalia ZNF839 34
  • 37 (a)
(Ornithorhynchus anatinus)
Mammalia ZNF839 34
  • 37 (a)
(Gallus gallus)
Aves ZNF839 34
  • 36 (a)
(Anolis carolinensis)
Reptilia ZNF839 34
  • 42 (a)
(Danio rerio)
Actinopterygii znf839 34
  • 21 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.453 34
  • 15 (a)
Species where no ortholog for ZNF839 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF839 Gene

Gene Tree for ZNF839 (if available)
Gene Tree for ZNF839 (if available)
Evolutionary constrained regions (ECRs) for ZNF839: view image

Paralogs for ZNF839 Gene

(2) SIMAP similar genes for ZNF839 Gene using alignment to 8 proteins:

  • ZN839_HUMAN
  • H0YM06_HUMAN
  • H0YM94_HUMAN
  • H0YNU6_HUMAN Pseudogenes for ZNF839 Gene

genes like me logo Genes that share paralogs with ZNF839: view

No data available for Paralogs for ZNF839 Gene

Variants for ZNF839 Gene

Sequence variations from dbSNP and Humsavar for ZNF839 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1000094381 -- 102,341,375(+) T/C coding_sequence_variant, intron_variant, synonymous_variant
rs1000185908 -- 102,317,170(+) A/G upstream_transcript_variant
rs1000513947 -- 102,319,606(+) C/T genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000850471 -- 102,340,314(+) C/G intron_variant
rs1000950847 -- 102,337,647(+) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF839 Gene

Variant ID Type Subtype PubMed ID
nsv827063 CNV gain 20364138
nsv827062 CNV gain 20364138
nsv1131164 CNV deletion 24896259
esv3635547 CNV gain 21293372
esv29657 CNV gain 19812545

Variation tolerance for ZNF839 Gene

Residual Variation Intolerance Score: 97.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.22; 81.05% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF839 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF839 Gene

Disorders for ZNF839 Gene

Additional Disease Information for ZNF839

No disorders were found for ZNF839 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF839 Gene

Publications for ZNF839 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. Polymorphisms in MicroRNA Binding Sites Predict Colorectal Cancer Survival. (PMID: 28138309) Yang YP … Bao BY (International journal of medical sciences 2017) 3 58
  3. Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor. (PMID: 27229929) Daakour S … Twizere JC (BMC cancer 2016) 3 58
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) Oláh J … Ovádi J (The Journal of biological chemistry 2011) 3 58
  5. A human MAP kinase interactome. (PMID: 20936779) Bandyopadhyay S … Ideker T (Nature methods 2010) 3 58

Products for ZNF839 Gene

Sources for ZNF839 Gene

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