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Aliases for ZNF837 Gene

Aliases for ZNF837 Gene

  • Zinc Finger Protein 837 2 3 5

External Ids for ZNF837 Gene

Previous GeneCards Identifiers for ZNF837 Gene

  • GC19M063571
  • GC19M058878
  • GC19M055188

Summaries for ZNF837 Gene

GeneCards Summary for ZNF837 Gene

ZNF837 (Zinc Finger Protein 837) is a Protein Coding gene. An important paralog of this gene is MECOM.

UniProtKB/Swiss-Prot for ZNF837 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF837 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF837 Gene

Genomics for ZNF837 Gene

GeneHancer (GH) Regulatory Elements for ZNF837 Gene

Promoters and enhancers for ZNF837 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I058379 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 561.8 0.0 -25 2.9 ZFP64 FEZF1 DMAP1 IRF4 SLC30A9 ZNF213 E2F8 ZNF143 SP3 NFYC ZNF837 LOC100128398 ZNF606 ZNF329 ZNF135 TRIM28 ZNF132 ZNF446 ZSCAN18 ZNF548
GH19I058406 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 18.9 -27.4 -27431 3.7 HDGF SMAD1 ARID4B SIN3A DMAP1 ZBTB7B YY1 SLC30A9 POLR2B ZNF766 ZNF584 ENSG00000232098 GC19M058405 PIR33627 TRIM28 LOC105372483 ZNF132 ZNF135 ZNF446 ZNF606
GH19I057476 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 13 +903.6 903582 1.5 PKNOX1 ATF1 FOXA2 MLX ARID4B SIN3A DMAP1 ZNF48 YY1 ETS1 ZNF772 ENSG00000268163 ENSG00000268266 ZNF773 ZNF417 VN1R1 ZNF446 ZNF606 ZNF134 ZNF17
GH19I058571 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 9.9 -193.2 -193159 4.8 CLOCK MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 MZF1 CENPBD1P1 TRIM28 ZSCAN18 ZNF446 LOC100128398 ZNF135 ZNF132 ZNF418 ENSG00000268201
GH19I058227 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 10.5 +152.1 152129 2.3 HDGF SMAD1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B ZNF207 ZNF544 ENSG00000283515 ZNF606 LOC105372483 ZNF135 ZNF329 MZF1-AS1 ZNF417 ZNF446 LOC100128398
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF837 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF837 gene promoter:

Genomic Locations for ZNF837 Gene

Genomic Locations for ZNF837 Gene
chr19:58,367,618-58,381,060
(GRCh38/hg38)
Size:
13,443 bases
Orientation:
Minus strand
chr19:58,878,985-58,892,427
(GRCh37/hg19)

Genomic View for ZNF837 Gene

Genes around ZNF837 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF837 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF837 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF837 Gene

Proteins for ZNF837 Gene

  • Protein details for ZNF837 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96EG3-ZN837_HUMAN
    Recommended name:
    Zinc finger protein 837
    Protein Accession:
    Q96EG3

    Protein attributes for ZNF837 Gene

    Size:
    531 amino acids
    Molecular mass:
    58078 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF837 Gene

Post-translational modifications for ZNF837 Gene

No Post-translational modifications

Other Protein References for ZNF837 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF837 Gene

Domains & Families for ZNF837 Gene

Gene Families for ZNF837 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF837 Gene

Suggested Antigen Peptide Sequences for ZNF837 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96EG3

UniProtKB/Swiss-Prot:

ZN837_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF837: view

Function for ZNF837 Gene

Molecular function for ZNF837 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF837 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF837: view

Phenotypes for ZNF837 Gene

GenomeRNAi human phenotypes for ZNF837:
genes like me logo Genes that share phenotypes with ZNF837: view

miRNA for ZNF837 Gene

miRTarBase miRNAs that target ZNF837

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF837 Gene

Localization for ZNF837 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF837 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF837 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF837 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF837: view

Pathways & Interactions for ZNF837 Gene

SuperPathways for ZNF837 Gene

No Data Available

Interacting Proteins for ZNF837 Gene

Gene Ontology (GO) - Biological Process for ZNF837 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF837: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF837 Gene

Drugs & Compounds for ZNF837 Gene

No Compound Related Data Available

Transcripts for ZNF837 Gene

mRNA/cDNA for ZNF837 Gene

Unigene Clusters for ZNF837 Gene

Zinc finger protein 837:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF837 Gene

ExUns: 1a · 1b ^ 2a · 2b
SP1:
SP2: -

Relevant External Links for ZNF837 Gene

GeneLoc Exon Structure for
ZNF837
ECgene alternative splicing isoforms for
ZNF837

Expression for ZNF837 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF837 Gene

Protein differential expression in normal tissues from HIPED for ZNF837 Gene

This gene is overexpressed in Lung (41.0) and Pancreatic juice (28.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF837 Gene



Protein tissue co-expression partners for ZNF837 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF837 Gene:

ZNF837

SOURCE GeneReport for Unigene cluster for ZNF837 Gene:

Hs.222236
genes like me logo Genes that share expression patterns with ZNF837: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF837 Gene

Orthologs for ZNF837 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF837 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF837 33
  • 98.93 (n)
dog
(Canis familiaris)
Mammalia ZNF837 33 34
  • 76.97 (n)
Species where no ortholog for ZNF837 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF837 Gene

ENSEMBL:
Gene Tree for ZNF837 (if available)
TreeFam:
Gene Tree for ZNF837 (if available)

Paralogs for ZNF837 Gene

Paralogs for ZNF837 Gene

(353) SIMAP similar genes for ZNF837 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF837: view

Variants for ZNF837 Gene

Sequence variations from dbSNP and Humsavar for ZNF837 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000096586 -- 58,381,908(-) T/A upstream_transcript_variant
rs1000539931 -- 58,371,164(-) C/A genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000550874 -- 58,381,168(-) A/C upstream_transcript_variant
rs1000596390 -- 58,376,354(-) C/G genic_upstream_transcript_variant, intron_variant
rs1000642632 -- 58,370,328(-) C/T 5_prime_UTR_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF837 Gene

Variant ID Type Subtype PubMed ID
nsv515731 CNV gain+loss 19592680
nsv817878 CNV loss 17921354
nsv833887 CNV loss 17160897
nsv833888 CNV loss 17160897

Variation tolerance for ZNF837 Gene

Gene Damage Index Score: 4.23; 62.26% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF837 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF837

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF837 Gene

Disorders for ZNF837 Gene

Additional Disease Information for ZNF837

No disorders were found for ZNF837 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF837 Gene

Publications for ZNF837 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58

Products for ZNF837 Gene

Sources for ZNF837 Gene

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