ZNF836 Gene (Protein Coding)

Zinc Finger Protein 836

GC19M052153
GIFtS:
31
See more...

Aliases for ZNF836 Gene

Aliases for ZNF836 Gene

  • Zinc Finger Protein 836 2 3 4 5
  • FLJ16287 2
  • ZNF836 5

External Ids for ZNF836 Gene

Previous GeneCards Identifiers for ZNF836 Gene

  • GC19M057352
  • GC19M052659
  • GC19M048989

Summaries for ZNF836 Gene

GeneCards Summary for ZNF836 Gene

ZNF836 (Zinc Finger Protein 836) is a Protein Coding gene. Among its related pathways are Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity. An important paralog of this gene is ZNF841.

UniProtKB/Swiss-Prot Summary for ZNF836 Gene

Additional gene information for ZNF836 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF836 Gene

Genomics for ZNF836 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for ZNF836 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF836 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF836

Top Transcription factor binding sites by QIAGEN in the ZNF836 gene promoter:
  • CBF(2)
  • CBF-A
  • CBF-B
  • CBF-C
  • CP1A
  • CP1C
  • GATA-1
  • NF-Y
  • NF-YA
  • NF-YB

Genomic Locations for ZNF836 Gene

Latest Assembly
chr19:52,153,864-52,171,664
(GRCh38/hg38)
Size:
17,801 bases
Orientation:
Minus strand

Previous Assembly
chr19:52,657,360-52,674,874
(GRCh37/hg19 by Entrez Gene)
Size:
17,515 bases
Orientation:
Minus strand

chr19:52,657,117-52,674,896
(GRCh37/hg19 by Ensembl)
Size:
17,780 bases
Orientation:
Minus strand

Genomic View for ZNF836 Gene

Genes around ZNF836 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF836 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF836 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for ZNF836 Gene

Proteins for ZNF836 Gene

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  • Protein details for ZNF836 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZNA1-ZN836_HUMAN
    Recommended name:
    Zinc finger protein 836
    Protein Accession:
    Q6ZNA1

    Protein attributes for ZNF836 Gene

    Size:
    936 amino acids
    Molecular mass:
    107717 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF836 Gene

Protein Expression for ZNF836 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for ZNF836 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF836 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF836 Gene

Domains & Families for ZNF836 Gene

Gene Families for ZNF836 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF836 Gene

InterPro:
Blocks:
  • C2H2-type zinc finger signature
  • KRAB box
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF836 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 836 (ZN836_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q6ZNA1

UniProtKB/Swiss-Prot:

ZN836_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF836: view

Function for ZNF836 Gene

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  3. miRNA products for research
  4. Inhibitory RNAs for research
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  6. Cell Lines for research

Molecular function for ZNF836 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF836 Gene

Gene Ontology (GO) - Molecular Function for ZNF836 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IBA 21873635
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific IBA 21873635
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF836: view
genes like me logo Genes that share phenotypes with ZNF836: view

Animal Models for research

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF836

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF836 Gene

Localization for ZNF836 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF836 Gene

Nucleus.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF836 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF836 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA 21873635
genes like me logo Genes that share ontologies with ZNF836: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF836 Gene

Pathways & Interactions for ZNF836 Gene

PathCards logo

SuperPathways for ZNF836 Gene

genes like me logo Genes that share pathways with ZNF836: view

Pathways by source for ZNF836 Gene

1 KEGG pathway for ZNF836 Gene

Gene Ontology (GO) - Biological Process for ZNF836 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006357 regulation of transcription by RNA polymerase II IBA 21873635
GO:0045944 positive regulation of transcription by RNA polymerase II IEA --
genes like me logo Genes that share ontologies with ZNF836: view

No data available for SIGNOR curated interactions for ZNF836 Gene

Drugs & Compounds for ZNF836 Gene

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No Compound Related Data Available

Transcripts for ZNF836 Gene

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mRNA/cDNA for ZNF836 Gene

1 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :
6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF836

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF836 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b · 7c · 7d
SP1: - - -
SP2: - - - -
SP3: - -
SP4: - - -
SP5: - - - - - -
SP6:

Relevant External Links for ZNF836 Gene

GeneLoc Exon Structure for
ZNF836

Expression for ZNF836 Gene

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  1. Primer products for research
  2. Gene Expression Assays for research

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF836 Gene

mRNA expression in normal human tissues for ZNF836 Gene
mRNA expression by BioGPS for ZNF836 GenemRNA expression by GTEx for ZNF836 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF836 Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF836

SOURCE GeneReport for Unigene cluster for ZNF836 Gene:

Hs.631584

Evidence on tissue expression from TISSUES for ZNF836 Gene

  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZNF836: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF836 Gene

Orthologs for ZNF836 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF836 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia ZNF836 30
  • 97.63 (n)
-- 31
  • 55 (a)
 ManyToMany
Cow
(Bos Taurus)
 Mammalia -- 31
  • 54 (a)
 ManyToMany
-- 31
  • 52 (a)
 ManyToMany
-- 31
  • 51 (a)
 ManyToMany
-- 31
  • 51 (a)
 ManyToMany
-- 31
  • 46 (a)
 ManyToMany
Mouse
(Mus musculus)
 Mammalia Zfp945 31
  • 39 (a)
 ManyToMany
Tropical Clawed Frog
(Silurana tropicalis)
 Amphibia LOC101734875 30
  • 54.58 (n)
Sea Squirt
(Ciona savignyi)
 Ascidiacea -- 31
  • 47 (a)
 ManyToMany
-- 31
  • 45 (a)
 ManyToMany
-- 31
  • 42 (a)
 ManyToMany
-- 31
  • 41 (a)
 ManyToMany
CSA.1668 31
  • 38 (a)
 ManyToMany
-- 31
  • 35 (a)
 ManyToMany
Species where no ortholog for ZNF836 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for ZNF836 Gene

ENSEMBL:
Gene Tree for ZNF836 (if available)
TreeFam:
Gene Tree for ZNF836 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF836: view image

Paralogs for ZNF836 Gene

Paralogs for ZNF836 Gene

(493) SIMAP similar genes for ZNF836 Gene using alignment to 4 proteins:

  • ZN836_HUMAN
  • M0QYS4_HUMAN
  • M0QZ88_HUMAN
  • M0R1N4_HUMAN

Pseudogenes.org Pseudogenes for ZNF836 Gene

genes like me logo Genes that share paralogs with ZNF836: view

Variants for ZNF836 Gene

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Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF836 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs1366245 - p.Met219Ile
rs8113504 - p.Asn809Ser

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for ZNF836 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for ZNF836 Gene

Variant ID Type Subtype PubMed ID
esv2718780 CNV deletion 23290073
esv2760529 CNV gain 21179565
esv2762047 CNV loss 21179565
esv3556561 CNV deletion 23714750
nsv1059417 CNV gain 25217958
nsv1140251 OTHER inversion 24896259
nsv580007 CNV gain 21841781
nsv817856 CNV gain 17921354
nsv960861 CNV duplication 23825009

Variation tolerance for ZNF836 Gene

Residual Variation Intolerance Score: 74.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.96; 89.91% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF836 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF836

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF836 Gene

Disorders for ZNF836 Gene

Additional Disease Information for ZNF836

Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform

No disorders were found for ZNF836 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF836 Gene

Publications for ZNF836 Gene

  1. An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. (PMID: 27173435) Boldt K … UK10K Rare Diseases Group (Nature communications 2016) 3
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

ExternalLinks

View latest publications for ZNF836 gene in Mastermind

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Sources for ZNF836 Gene