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Aliases for ZNF836 Gene

Aliases for ZNF836 Gene

  • Zinc Finger Protein 836 2 3 5

External Ids for ZNF836 Gene

Previous GeneCards Identifiers for ZNF836 Gene

  • GC19M057352
  • GC19M052659
  • GC19M048989

Summaries for ZNF836 Gene

GeneCards Summary for ZNF836 Gene

ZNF836 (Zinc Finger Protein 836) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA binding transcription factor activity. An important paralog of this gene is ZNF841.

UniProtKB/Swiss-Prot for ZNF836 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF836 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF836 Gene

Genomics for ZNF836 Gene

GeneHancer (GH) Regulatory Elements for ZNF836 Gene

Promoters and enhancers for ZNF836 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I052170 Promoter/Enhancer 2.1 EPDnew FANTOM5 Ensembl ENCODE 552.5 +0.2 215 2.5 HDGF SMAD1 ZSCAN4 ARID4B SIN3A ZNF48 ZBTB40 ZNF335 ZNF121 ZNF366 ZNF836 ENSG00000267827 ENSG00000267927 FPR3 PPP2R1A
GH19I051687 Promoter/Enhancer 2.1 FANTOM5 Ensembl ENCODE dbSUPER 76.3 +481.2 481176 6.9 HDGF PKNOX1 ARNT SIN3A FEZF1 ZNF2 ZBTB7B E2F8 ZNF207 ZNF143 ZNF137P ZNF808 ZNF841 ZNF616 ZNF766 ZNF577 ENSG00000268970 ZNF836 ENSG00000269825 ZNF175
GH19I051393 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE 74.8 +776.6 776620 2.8 HDGF PKNOX1 SMAD1 ARNT ZFP64 ARID4B SIN3A IRF4 YY1 POLR2B ENSG00000268889 LOC105372446 ZNF841 ZNF766 ZNF577 ZNF616 ZNF175 ZNF836 ZNF432 ZNF614
GH19I052137 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE 39.1 +32.0 32035 3.3 PKNOX1 FOXA2 SMAD1 ARNT ARID4B SIN3A DMAP1 YY1 POLR2B E2F8 ZNF616 ZNF137P ZNF160 ZNF808 ENSG00000268970 ZNF600 ZNF350 ZNF816 ZNF836 ZNF577
GH19I051360 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 29 +806.7 806724 8.5 MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC PPARGC1A MEF2D ETFB CLDND2 ENSG00000268520 ZNF616 POLD1 ZNF766 ZNF836 ZNF841 ZNF577 ZNF175
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF836 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF836 gene promoter:

Genomic Locations for ZNF836 Gene

Genomic Locations for ZNF836 Gene
chr19:52,153,864-52,171,667
(GRCh38/hg38)
Size:
17,804 bases
Orientation:
Minus strand
chr19:52,657,117-52,674,896
(GRCh37/hg19)

Genomic View for ZNF836 Gene

Genes around ZNF836 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF836 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF836 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF836 Gene

Proteins for ZNF836 Gene

  • Protein details for ZNF836 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZNA1-ZN836_HUMAN
    Recommended name:
    Zinc finger protein 836
    Protein Accession:
    Q6ZNA1

    Protein attributes for ZNF836 Gene

    Size:
    936 amino acids
    Molecular mass:
    107717 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF836 Gene

Post-translational modifications for ZNF836 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ZNF836 Gene

Domains & Families for ZNF836 Gene

Gene Families for ZNF836 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Suggested Antigen Peptide Sequences for ZNF836 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZNA1

UniProtKB/Swiss-Prot:

ZN836_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF836: view

Function for ZNF836 Gene

Molecular function for ZNF836 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF836 Gene

Gene Ontology (GO) - Molecular Function for ZNF836 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF836: view

Phenotypes for ZNF836 Gene

genes like me logo Genes that share phenotypes with ZNF836: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF836 Gene

Localization for ZNF836 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF836 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF836 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF836 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF836: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF836 Gene

Pathways & Interactions for ZNF836 Gene

SuperPathways for ZNF836 Gene

No Data Available

Interacting Proteins for ZNF836 Gene

Gene Ontology (GO) - Biological Process for ZNF836 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
genes like me logo Genes that share ontologies with ZNF836: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF836 Gene

Drugs & Compounds for ZNF836 Gene

No Compound Related Data Available

Transcripts for ZNF836 Gene

Unigene Clusters for ZNF836 Gene

Zinc finger protein 836:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF836 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b · 7c · 7d
SP1: - - -
SP2: - - - -
SP3: - -
SP4: - - -
SP5: - - - - - -
SP6:

Relevant External Links for ZNF836 Gene

GeneLoc Exon Structure for
ZNF836
ECgene alternative splicing isoforms for
ZNF836

Expression for ZNF836 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF836 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF836 Gene



NURSA nuclear receptor signaling pathways regulating expression of ZNF836 Gene:

ZNF836

SOURCE GeneReport for Unigene cluster for ZNF836 Gene:

Hs.631584

Evidence on tissue expression from TISSUES for ZNF836 Gene

  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZNF836: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF836 Gene

Orthologs for ZNF836 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF836 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF836 33
  • 97.63 (n)
-- 34
  • 55 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 34
  • 54 (a)
ManyToMany
-- 34
  • 52 (a)
ManyToMany
-- 34
  • 51 (a)
ManyToMany
-- 34
  • 51 (a)
ManyToMany
-- 34
  • 46 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp945 34
  • 39 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101734875 33
  • 54.58 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 47 (a)
ManyToMany
-- 34
  • 45 (a)
ManyToMany
-- 34
  • 42 (a)
ManyToMany
-- 34
  • 41 (a)
ManyToMany
CSA.1668 34
  • 38 (a)
ManyToMany
-- 34
  • 35 (a)
ManyToMany
Species where no ortholog for ZNF836 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF836 Gene

ENSEMBL:
Gene Tree for ZNF836 (if available)
TreeFam:
Gene Tree for ZNF836 (if available)

Paralogs for ZNF836 Gene

Paralogs for ZNF836 Gene

(493) SIMAP similar genes for ZNF836 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF836: view

Variants for ZNF836 Gene

Sequence variations from dbSNP and Humsavar for ZNF836 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000094793 -- 52,168,660(-) C/G intron_variant
rs1000143487 -- 52,163,497(-) G/A intron_variant
rs1000381772 -- 52,157,908(-) T/C intron_variant
rs1000441395 -- 52,169,608(-) AAAAAAAAA/AAAAAAAAAA intron_variant
rs1000494228 -- 52,163,595(-) A/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF836 Gene

Variant ID Type Subtype PubMed ID
nsv960861 CNV duplication 23825009
nsv817856 CNV gain 17921354
nsv580007 CNV gain 21841781
nsv1140251 OTHER inversion 24896259
nsv1059417 CNV gain 25217958
esv3556561 CNV deletion 23714750
esv2762047 CNV loss 21179565
esv2760529 CNV gain 21179565
esv2718780 CNV deletion 23290073

Variation tolerance for ZNF836 Gene

Residual Variation Intolerance Score: 74.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.96; 89.91% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF836 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF836

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF836 Gene

Disorders for ZNF836 Gene

Additional Disease Information for ZNF836

No disorders were found for ZNF836 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF836 Gene

Publications for ZNF836 Gene

  1. An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. (PMID: 27173435) Boldt K … UK10K Rare Diseases Group (Nature communications 2016) 3 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 58
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for ZNF836 Gene

Sources for ZNF836 Gene

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