Aliases for ZNF830 Gene
External Ids for ZNF830 Gene
Previous HGNC Symbols for ZNF830 Gene
Previous GeneCards Identifiers for ZNF830 Gene
GeneCards Summary for ZNF830 Gene
ZNF830 (Zinc Finger Protein 830) is a Protein Coding gene. Diseases associated with ZNF830 include Xeroderma Pigmentosum, Complementation Group A and Fanconi Anemia, Complementation Group F. Among its related pathways are Transcription-Coupled Nucleotide Excision Repair (TC-NER) and DNA Double-Strand Break Repair. Gene Ontology (GO) annotations related to this gene include nucleic acid binding.
UniProtKB/Swiss-Prot Summary for ZNF830 Gene
May play a role in pre-mRNA splicing as component of the spliceosome (PubMed:25599396). Acts as an important regulator of the cell cycle that participates in the maintenance of genome integrity. During cell cycle progression in embryonic fibroblast, prevents replication fork collapse, double-strand break formation and cell cycle checkpoint activation. Controls mitotic cell cycle progression and cell survival in rapidly proliferating intestinal epithelium and embryonic stem cells. During the embryo preimplantation, controls different aspects of M phase. During early oocyte growth, plays a role in oocyte survival by preventing chromosomal breaks formation, activation of TP63 and reduction of transcription (By similarity).