Aliases for ZNF823 Gene

Aliases for ZNF823 Gene

  • Zinc Finger Protein 823 2 3 4 5
  • ZFP 36 For A Zinc Finger Protein 2 3
  • Zinc Finger Protein ZFP-36 3 4
  • HSZFP36 3
  • ZFP36 4

External Ids for ZNF823 Gene

Previous GeneCards Identifiers for ZNF823 Gene

  • GC19M011700
  • GC19M011832
  • GC19M011410

Summaries for ZNF823 Gene

GeneCards Summary for ZNF823 Gene

ZNF823 (Zinc Finger Protein 823) is a Protein Coding gene. Diseases associated with ZNF823 include Corneal Dystrophy, Band-Shaped. Among its related pathways are Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF443.

UniProtKB/Swiss-Prot Summary for ZNF823 Gene

Additional gene information for ZNF823 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF823 Gene

Genomics for ZNF823 Gene

GeneHancer (GH) Regulatory Elements for ZNF823 Gene

Promoters and enhancers for ZNF823 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J011737 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas 500.7 +0.3 341 2.5 ZBTB40 ZNF217 EP300 NRF1 POLR2G SP1 NCOR1 ZFX ZNF639 ZNF10 RF00017-2822 RF00017-2823 ZNF823 ZNF625 ENSG00000242615 ZNF441 ZNF491 ZNF709 ZNF136 TIMM29
GH19J012732 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas 13 -996.7 -996692 6.2 RXRA EP300 FOXK2 ZBTB40 ZNF217 CTCF SIN3A NRF1 TCF12 POLR2G TRIR GET3 ZNF700 ZNF136 CCDC130 ZNF44 WDR83OS ZNF564 ZNF799 ZNF791
GH19J012609 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas 10.4 -873.1 -873066 5.4 FOXK2 ZBTB40 ZNF217 EP300 SIN3A NRF1 MYC POLR2G SP1 NCOR1 ZNF490 ZNF791 piR-44933 ZNF136 ZNF20 ZNF44 FBXW9 ZNF799 ZNF700 ZNF441
GH19J011693 Promoter/Enhancer 1.5 FANTOM5 ENCODE CraniofacialAtlas 13.4 +44.4 44448 2.1 CTCF ZSCAN5C MYC POLR2G SP1 ZIC2 POLR2A AFF1 ZBTB26 ZNF510 ZNF441 ZNF439 ZNF709 ZNF136 ZNF763 ZNF823 ZNF788P WDR83 ZNF20 ENSG00000242615
GH19J010758 Promoter/Enhancer 1.5 Ensembl ENCODE dbSUPER 13 +975.8 975848 8.9 EP300 ZBTB40 SIN3A POLR2G SP1 NCOR1 ZIC2 KDM6A TCF7 KLF4 KRI1 FBXL12 ILF3 RAVER1 ZNF823 PPAN MIR199A1 SLC44A2 MIR638 DNM2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF823 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF823

Genomic Locations for ZNF823 Gene

Genomic Locations for ZNF823 Gene
17,745 bases
Minus strand
17,745 bases
Minus strand

Genomic View for ZNF823 Gene

Genes around ZNF823 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF823 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF823 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF823 Gene

Proteins for ZNF823 Gene

  • Protein details for ZNF823 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 823
    Protein Accession:
    Secondary Accessions:
    • A0PJL4
    • B7Z8D4
    • Q6P4A9

    Protein attributes for ZNF823 Gene

    610 amino acids
    Molecular mass:
    70270 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAA36064.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF823 Gene


neXtProt entry for ZNF823 Gene

Post-translational modifications for ZNF823 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF823 Gene

Domains & Families for ZNF823 Gene

Gene Families for ZNF823 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF823 Gene

  • KRAB box

Suggested Antigen Peptide Sequences for ZNF823 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ61600, highly similar to Zinc finger protein ZFP-36 (B7Z8D4_HUMAN)
  • Zinc finger protein ZFP-36 (ZN823_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF823: view

Function for ZNF823 Gene

Molecular function for ZNF823 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF823 Gene

Gene Ontology (GO) - Molecular Function for ZNF823 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF823: view
genes like me logo Genes that share phenotypes with ZNF823: view

miRNA for ZNF823 Gene

miRTarBase miRNAs that target ZNF823

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF823 Gene

Localization for ZNF823 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF823 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF823 gene
Compartment Confidence
nucleus 4
cytosol 2
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for ZNF823 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF823: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF823 Gene

Pathways & Interactions for ZNF823 Gene

PathCards logo

SuperPathways for ZNF823 Gene

genes like me logo Genes that share pathways with ZNF823: view

Pathways by source for ZNF823 Gene

1 KEGG pathway for ZNF823 Gene

Interacting Proteins for ZNF823 Gene


Gene Ontology (GO) - Biological Process for ZNF823 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF823: view

No data available for SIGNOR curated interactions for ZNF823 Gene

Drugs & Compounds for ZNF823 Gene

No Compound Related Data Available

Transcripts for ZNF823 Gene

mRNA/cDNA for ZNF823 Gene

8 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF823 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d
SP2: -
SP3: -
SP4: - -

Relevant External Links for ZNF823 Gene

GeneLoc Exon Structure for

Expression for ZNF823 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF823 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF823 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF823

SOURCE GeneReport for Unigene cluster for ZNF823 Gene:

genes like me logo Genes that share expression patterns with ZNF823: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF823 Gene

Orthologs for ZNF823 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF823 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF823 30
  • 99.56 (n)
(Bos Taurus)
Mammalia -- 31
  • 50 (a)
Species where no ortholog for ZNF823 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF823 Gene

Gene Tree for ZNF823 (if available)
Gene Tree for ZNF823 (if available)
Evolutionary constrained regions (ECRs) for ZNF823: view image

Paralogs for ZNF823 Gene

(521) SIMAP similar genes for ZNF823 Gene using alignment to 5 proteins:

  • ZN823_HUMAN
  • B7Z8D4_HUMAN
  • C9J2N8_HUMAN
  • C9JU45_HUMAN
  • K7EN93_HUMAN
genes like me logo Genes that share paralogs with ZNF823: view

Variants for ZNF823 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF823 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs3745663 - p.Arg566His

Additional dbSNP identifiers (rs#s) for ZNF823 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF823 Gene

Variant ID Type Subtype PubMed ID
nsv1072325 CNV deletion 25765185
nsv518441 CNV loss 19592680
nsv522659 CNV loss 19592680
nsv525966 CNV gain 19592680
nsv960789 CNV duplication 23825009

Variation tolerance for ZNF823 Gene

Residual Variation Intolerance Score: 34.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.23; 24.57% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF823 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF823 Gene

Disorders for ZNF823 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZNF823 Gene - From: DISEASES

Disorder Aliases PubMed IDs
corneal dystrophy, band-shaped
  • band keratopathy
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for ZNF823

genes like me logo Genes that share disorders with ZNF823: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF823 Gene

Publications for ZNF823 Gene

  1. A human MAP kinase interactome. (PMID: 20936779) Bandyopadhyay S … Ideker T (Nature methods 2010) 3 54
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 54
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 54
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 54
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 54

Products for ZNF823 Gene

Sources for ZNF823 Gene