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Aliases for ZNF823 Gene

Aliases for ZNF823 Gene

  • Zinc Finger Protein 823 2 3 5
  • ZFP 36 For A Zinc Finger Protein 2 3
  • Zinc Finger Protein ZFP-36 3 4
  • HSZFP36 3
  • ZFP36 4

External Ids for ZNF823 Gene

Previous GeneCards Identifiers for ZNF823 Gene

  • GC19M011700
  • GC19M011832
  • GC19M011410

Summaries for ZNF823 Gene

GeneCards Summary for ZNF823 Gene

ZNF823 (Zinc Finger Protein 823) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF442.

UniProtKB/Swiss-Prot for ZNF823 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF823 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF823 Gene

Genomics for ZNF823 Gene

GeneHancer (GH) Regulatory Elements for ZNF823 Gene

Promoters and enhancers for ZNF823 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I011737 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 +0.3 254 2.4 HDGF PKNOX1 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 POLR2B ZNF766 ZNF823 ZNF878 ZNF44 ZNF20 TIMM29 ZNF136 ZNF763 ZNF441 ZNF700 ZNF564
GH19I011373 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 23.8 +362.7 362689 6.2 HDGF PKNOX1 SMAD1 ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ENSG00000267277 PIR61774 SWSAP1 ILF3 KRI1 ZNF627 ZNF136 ZNF442 ZNF844 ZNF44
GH19I012609 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE 22 -873.4 -873352 4.8 HDGF PKNOX1 SMAD1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 IRF4 ZNF490 ZNF791 PIR37932 ZNF136 ZNF44 ZNF20 ZNF700 ZNF799 ZNF442 ZNF844
GH19I012720 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 23.7 -983.4 -983367 4.2 CLOCK MLX DMAP1 IRF4 YY1 SLC30A9 E2F8 ZNF143 SP3 NFYC TNPO2 ZNF136 TRMT1 ZNF44 ZNF700 ZNF564 ZNF799 WDR83OS ZNF763 ZNF791
GH19I012733 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 20.2 -996.8 -996829 5.7 CLOCK ZFP64 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 TRIR ASNA1 ZNF136 CCDC130 ZNF44 ZNF564 WDR83OS ZNF700 ZNF791 ZNF878
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF823 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZNF823 Gene

Genomic Locations for ZNF823 Gene
chr19:11,721,265-11,739,009
(GRCh38/hg38)
Size:
17,745 bases
Orientation:
Minus strand
chr19:11,832,080-11,849,824
(GRCh37/hg19)

Genomic View for ZNF823 Gene

Genes around ZNF823 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF823 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF823 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF823 Gene

Proteins for ZNF823 Gene

  • Protein details for ZNF823 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P16415-ZN823_HUMAN
    Recommended name:
    Zinc finger protein 823
    Protein Accession:
    P16415
    Secondary Accessions:
    • A0PJL4
    • B7Z8D4
    • Q6P4A9

    Protein attributes for ZNF823 Gene

    Size:
    610 amino acids
    Molecular mass:
    70270 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAA36064.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF823 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF823 Gene

Post-translational modifications for ZNF823 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF823 Gene

No data available for DME Specific Peptides for ZNF823 Gene

Domains & Families for ZNF823 Gene

Gene Families for ZNF823 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF823 Gene

Suggested Antigen Peptide Sequences for ZNF823 Gene

Graphical View of Domain Structure for InterPro Entry

P16415

UniProtKB/Swiss-Prot:

ZN823_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF823: view

Function for ZNF823 Gene

Molecular function for ZNF823 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF823 Gene

Gene Ontology (GO) - Molecular Function for ZNF823 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF823: view
genes like me logo Genes that share phenotypes with ZNF823: view

miRNA for ZNF823 Gene

miRTarBase miRNAs that target ZNF823

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF823 Gene

Localization for ZNF823 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF823 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF823 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF823 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF823: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF823 Gene

Pathways & Interactions for ZNF823 Gene

SuperPathways for ZNF823 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF823 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF823: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF823 Gene

Drugs & Compounds for ZNF823 Gene

No Compound Related Data Available

Transcripts for ZNF823 Gene

Unigene Clusters for ZNF823 Gene

Zinc finger protein 823:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF823 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d
SP1:
SP2: -
SP3: -
SP4: - -

Relevant External Links for ZNF823 Gene

GeneLoc Exon Structure for
ZNF823
ECgene alternative splicing isoforms for
ZNF823

Expression for ZNF823 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF823 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF823 Gene



NURSA nuclear receptor signaling pathways regulating expression of ZNF823 Gene:

ZNF823

SOURCE GeneReport for Unigene cluster for ZNF823 Gene:

Hs.142167
genes like me logo Genes that share expression patterns with ZNF823: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF823 Gene

Orthologs for ZNF823 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF823 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF823 33
  • 99.56 (n)
cow
(Bos Taurus)
Mammalia -- 34
  • 50 (a)
ManyToMany
Species where no ortholog for ZNF823 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF823 Gene

ENSEMBL:
Gene Tree for ZNF823 (if available)
TreeFam:
Gene Tree for ZNF823 (if available)

Paralogs for ZNF823 Gene

(521) SIMAP similar genes for ZNF823 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF823: view

Variants for ZNF823 Gene

Sequence variations from dbSNP and Humsavar for ZNF823 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000042601 -- 11,737,869(-) T/C intron_variant
rs1000203227 -- 11,721,080(-) G/T downstream_transcript_variant
rs1000876596 -- 11,725,530(-) A/G intron_variant
rs1000892316 -- 11,737,822(-) AGGAGGAG/AGGAG intron_variant
rs1001093263 -- 11,724,589(-) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF823 Gene

Variant ID Type Subtype PubMed ID
nsv1072325 CNV deletion 25765185
nsv518441 CNV loss 19592680
nsv522659 CNV loss 19592680
nsv525966 CNV gain 19592680
nsv960789 CNV duplication 23825009

Variation tolerance for ZNF823 Gene

Residual Variation Intolerance Score: 34.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.23; 24.57% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF823 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF823

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF823 Gene

Disorders for ZNF823 Gene

Additional Disease Information for ZNF823

No disorders were found for ZNF823 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF823 Gene

Publications for ZNF823 Gene

  1. A human MAP kinase interactome. (PMID: 20936779) Bandyopadhyay S … Ideker T (Nature methods 2010) 3 58
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 58
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58

Products for ZNF823 Gene

Sources for ZNF823 Gene

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