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Aliases for ZNF816-ZNF321P Gene

Aliases for ZNF816-ZNF321P Gene

  • ZNF816-ZNF321P Readthrough 2 3 5
  • ZNF816-ZNF321 Readthrough 2 3
  • ZNF816-ZNF321 Read-Through Transcript 3
  • ZNF816-ZNF321 Protein 3
  • ZNF816-ZNF321 3

External Ids for ZNF816-ZNF321P Gene

Previous HGNC Symbols for ZNF816-ZNF321P Gene

  • ZNF816-ZNF321

Previous GeneCards Identifiers for ZNF816-ZNF321P Gene

  • GC19U901533
  • GC19M053434
  • GC19M053436

Summaries for ZNF816-ZNF321P Gene

Entrez Gene Summary for ZNF816-ZNF321P Gene

  • This locus represents naturally occurring read-through transcription between the zinc finger protein 816 (ZNF816) gene and the zinc finger protein 321 (ZNF321) pseudogene on chromosome 19. The read-through transcript encodes a KRAB domain-containing protein that shares sequence identity with the upstream gene product, but it contains a distinct C-terminus encoded by exon structure from the downstream pseudogene. [provided by RefSeq, Jan 2011]

GeneCards Summary for ZNF816-ZNF321P Gene

ZNF816-ZNF321P (ZNF816-ZNF321P Readthrough) is a Protein Coding gene. An important paralog of this gene is ZNF816.

Additional gene information for ZNF816-ZNF321P Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF816-ZNF321P Gene

Genomics for ZNF816-ZNF321P Gene

GeneHancer (GH) Regulatory Elements for ZNF816-ZNF321P Gene

Promoters and enhancers for ZNF816-ZNF321P Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I052961 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 +0.3 253 2.5 HDGF ATF1 ARID4B SIN3A DMAP1 ETS1 POLR2B GLIS2 E2F8 ZNF143 ZNF816 ENSG00000283088 ZNF816-ZNF321P ZNF137P ZNF665 ENSG00000268970 ZNF701 ZNF611 ENSG00000269001 TPM3P9
GH19I052941 Promoter/Enhancer 2.2 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +18.4 18418 6.1 HDGF PKNOX1 FOXA2 SMAD1 MLX ARID4B SIN3A DMAP1 POLR2B E2F8 ZNF321P ZNF816 ZNF160 VN1R2 ZNF677 ZNF665 ZNF761 ZNF347 ZNF415 ZNF83
GH19I052934 Enhancer 1.4 Ensembl ENCODE dbSUPER 0.3 +25.1 25129 5.9 PKNOX1 FOXA2 ARNT ZNF766 CBX5 E2F8 JUNB REST ZNF592 MEF2D ZNF816 ENSG00000268225 ZNF83 ZNF321P ZNF888 ENSG00000283088 ZNF816-ZNF321P
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF816-ZNF321P on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZNF816-ZNF321P Gene

Genomic Locations for ZNF816-ZNF321P Gene
35,777 bases
Minus strand

Genomic View for ZNF816-ZNF321P Gene

Genes around ZNF816-ZNF321P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF816-ZNF321P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF816-ZNF321P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF816-ZNF321P Gene

Proteins for ZNF816-ZNF321P Gene

  • Protein details for ZNF816-ZNF321P Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    ZNF816-ZNF321P readthrough
    Protein Accession:

    Protein attributes for ZNF816-ZNF321P Gene

    233 amino acids
    Molecular mass:
    27027 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF816-ZNF321P Gene

Post-translational modifications for ZNF816-ZNF321P Gene

No Post-translational modifications

Other Protein References for ZNF816-ZNF321P Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF816-ZNF321P Gene

Domains & Families for ZNF816-ZNF321P Gene

Gene Families for ZNF816-ZNF321P Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF816-ZNF321P Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZNF816-ZNF321P: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ZNF816-ZNF321P Gene

Function for ZNF816-ZNF321P Gene

Phenotypes From GWAS Catalog for ZNF816-ZNF321P Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF816-ZNF321P Gene

Localization for ZNF816-ZNF321P Gene

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF816-ZNF321P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with ZNF816-ZNF321P: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for ZNF816-ZNF321P Gene

Pathways & Interactions for ZNF816-ZNF321P Gene

SuperPathways for ZNF816-ZNF321P Gene

No Data Available

Interacting Proteins for ZNF816-ZNF321P Gene

Gene Ontology (GO) - Biological Process for ZNF816-ZNF321P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF816-ZNF321P: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF816-ZNF321P Gene

Drugs & Compounds for ZNF816-ZNF321P Gene

No Compound Related Data Available

Transcripts for ZNF816-ZNF321P Gene

mRNA/cDNA for ZNF816-ZNF321P Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF816-ZNF321P Gene

ZNF816-ZNF321P readthrough:
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF816-ZNF321P Gene

No ASD Table

Relevant External Links for ZNF816-ZNF321P Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF816-ZNF321P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF816-ZNF321P Gene

mRNA differential expression in normal tissues according to GTEx for ZNF816-ZNF321P Gene

This gene is overexpressed in Bladder (x5.7).

SOURCE GeneReport for Unigene cluster for ZNF816-ZNF321P Gene:

genes like me logo Genes that share expression patterns with ZNF816-ZNF321P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF816-ZNF321P Gene

Orthologs for ZNF816-ZNF321P Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF816-ZNF321P Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF321P 34
  • 93 (a)
(Canis familiaris)
Mammalia -- 34
  • 18 (a)
(Bos Taurus)
Mammalia -- 34
  • 15 (a)
Species where no ortholog for ZNF816-ZNF321P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF816-ZNF321P Gene

Gene Tree for ZNF816-ZNF321P (if available)
Gene Tree for ZNF816-ZNF321P (if available)

Paralogs for ZNF816-ZNF321P Gene

genes like me logo Genes that share paralogs with ZNF816-ZNF321P: view

Variants for ZNF816-ZNF321P Gene

Sequence variations from dbSNP and Humsavar for ZNF816-ZNF321P Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000057187 -- 52,942,624(-) C/G/T intron_variant
rs1000116311 -- 52,962,827(-) A/C 5_prime_UTR_variant
rs1000146635 -- 52,964,620(-) G/T upstream_transcript_variant
rs1000148071 -- 52,940,047(-) G/A intron_variant
rs1000212551 -- 52,963,192(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF816-ZNF321P Gene

Variant ID Type Subtype PubMed ID
nsv963071 CNV duplication 23825009
nsv580030 CNV gain 21841781
nsv522421 CNV loss 19592680
nsv428370 CNV loss 18775914
nsv2539 CNV deletion 18451855
nsv1140479 CNV deletion 24896259
nsv1127696 CNV deletion 24896259
nsv1078889 OTHER inversion 25765185
nsv1066762 CNV gain 25217958
nsv1064234 CNV gain 25217958
nsv1057118 CNV gain 25217958
esv3893234 CNV gain 25118596
esv3644727 CNV gain 21293372
esv2758769 CNV loss 17122850
esv2718808 CNV deletion 23290073
esv2718804 CNV deletion 23290073
esv2718799 CNV deletion 23290073
esv2718796 CNV deletion 23290073
esv2718787 CNV deletion 23290073
esv2718786 CNV deletion 23290073

Variation tolerance for ZNF816-ZNF321P Gene

Residual Variation Intolerance Score: 81.5% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF816-ZNF321P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF816-ZNF321P Gene

Disorders for ZNF816-ZNF321P Gene

Additional Disease Information for ZNF816-ZNF321P

No disorders were found for ZNF816-ZNF321P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF816-ZNF321P Gene

Publications for ZNF816-ZNF321P Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 58
  2. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 3 58
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 58

Products for ZNF816-ZNF321P Gene

Sources for ZNF816-ZNF321P Gene

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