Aliases for ZNF814 Gene

Aliases for ZNF814 Gene

  • Zinc Finger Protein 814 2 3 4 5
  • ZNF814 5

External Ids for ZNF814 Gene

Previous GeneCards Identifiers for ZNF814 Gene

  • GC19U900727
  • GC19M063072
  • GC19M058380
  • GC19M054692
  • GC19M058361

Summaries for ZNF814 Gene

GeneCards Summary for ZNF814 Gene

ZNF814 (Zinc Finger Protein 814) is a Protein Coding gene. Among its related pathways are Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity. An important paralog of this gene is ZNF268.

Additional gene information for ZNF814 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF814 Gene

Genomics for ZNF814 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZNF814 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF814 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF814

Top Transcription factor binding sites by QIAGEN in the ZNF814 gene promoter:
  • aMEF-2
  • FOXI1
  • HFH-3
  • MEF-2A
  • Nkx6-1
  • RSRFC4

Genomic Locations for ZNF814 Gene

Genomic Locations for ZNF814 Gene
40,344 bases
Minus strand
40,344 bases
Minus strand

Genomic View for ZNF814 Gene

Genes around ZNF814 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF814 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF814 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF814 Gene

Proteins for ZNF814 Gene

  • Protein details for ZNF814 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 814
    Protein Accession:
    Secondary Accessions:
    • A6NF35

    Protein attributes for ZNF814 Gene

    855 amino acids
    Molecular mass:
    97337 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF814 Gene

Post-translational modifications for ZNF814 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF814 Gene

Domains & Families for ZNF814 Gene

Gene Families for ZNF814 Gene

Human Protein Atlas (HPA):
  • Cancer-related genes
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF814 Gene

Suggested Antigen Peptide Sequences for ZNF814 Gene

GenScript: Design optimal peptide antigens:
  • Putative zinc finger protein LOC730051 (ZN814_HUMAN)
genes like me logo Genes that share domains with ZNF814: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ZNF814 Gene

Function for ZNF814 Gene

Gene Ontology (GO) - Molecular Function for ZNF814 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IBA --
GO:0003700 DNA-binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF814: view

Animal Model Products

CRISPR Products

miRNA for ZNF814 Gene

miRTarBase miRNAs that target ZNF814

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF814

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF814 Gene

Localization for ZNF814 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF814 gene
Compartment Confidence
nucleus 4
cytoskeleton 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF814 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZNF814: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ZNF814 Gene

Pathways & Interactions for ZNF814 Gene

PathCards logo

SuperPathways for ZNF814 Gene

genes like me logo Genes that share pathways with ZNF814: view

Pathways by source for ZNF814 Gene

1 KEGG pathway for ZNF814 Gene

Interacting Proteins for ZNF814 Gene

Gene Ontology (GO) - Biological Process for ZNF814 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF814: view

No data available for SIGNOR curated interactions for ZNF814 Gene

Drugs & Compounds for ZNF814 Gene

No Compound Related Data Available

Transcripts for ZNF814 Gene

mRNA/cDNA for ZNF814 Gene

8 NCBI additional mRNA sequence :
15 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF814

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF814 Gene

No ASD Table

Relevant External Links for ZNF814 Gene

GeneLoc Exon Structure for

Expression for ZNF814 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF814 Gene

Protein differential expression in normal tissues from HIPED for ZNF814 Gene

This gene is overexpressed in Lung (57.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF814 Gene

Protein tissue co-expression partners for ZNF814 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF814

SOURCE GeneReport for Unigene cluster for ZNF814 Gene:

genes like me logo Genes that share expression patterns with ZNF814: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF814 Gene

Orthologs for ZNF814 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF814 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF814 30
  • 96.45 (n)
(Canis familiaris)
Mammalia LOC102152013 30
  • 67.42 (n)
-- 31
  • 45 (a)
-- 31
  • 40 (a)
(Bos Taurus)
Mammalia ZNF154 30
  • 67.3 (n)
-- 31
  • 50 (a)
-- 31
  • 50 (a)
-- 31
  • 41 (a)
-- 31
  • 39 (a)
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 38 (a)
(Gallus gallus)
Aves ZNF814 31
  • 41 (a)
(Anolis carolinensis)
Reptilia ZNF814 31
  • 39 (a)
(Danio rerio)
Actinopterygii CU672268.1 31
  • 43 (a)
si:zfos-44a5.2 31
  • 43 (a)
AL954741.1 31
  • 42 (a)
CABZ01006831.1 31
  • 41 (a)
BX640537.2 31
  • 41 (a)
CABZ01075191.1 31
  • 41 (a)
zgc:174712 31
  • 40 (a)
si:ch211-235i11.2 31
  • 40 (a)
CABZ01006835.1 31
  • 38 (a)
CABZ01048402.1 31
  • 37 (a)
zgc:113389 31
  • 36 (a)
BX000701.1 31
  • 36 (a)
si:dkey-20i20.5 31
  • 36 (a)
FP326649.1 31
  • 35 (a)
Species where no ortholog for ZNF814 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for ZNF814 Gene

Gene Tree for ZNF814 (if available)
Gene Tree for ZNF814 (if available)
Evolutionary constrained regions (ECRs) for ZNF814: view image

Paralogs for ZNF814 Gene

Paralogs for ZNF814 Gene

(532) SIMAP similar genes for ZNF814 Gene using alignment to 9 proteins:

  • ZN814_HUMAN
  • M0QY74_HUMAN
  • M0QZ45_HUMAN
  • M0QZ64_HUMAN
  • M0R066_HUMAN
  • M0R0R0_HUMAN
genes like me logo Genes that share paralogs with ZNF814: view

Variants for ZNF814 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF814 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs1555777007 Not Provided: not provided 57,873,497(-) AG/A FRAMESHIFT_VARIANT

Additional dbSNP identifiers (rs#s) for ZNF814 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF814 Gene

Variant ID Type Subtype PubMed ID
dgv3686n100 CNV gain 25217958
esv1001775 CNV deletion 20482838
esv2302097 CNV deletion 18987734
esv2719092 CNV deletion 23290073
esv2719093 CNV deletion 23290073
esv2763213 CNV gain 21179565
esv3644913 CNV gain 21293372
esv3644914 CNV loss 21293372
esv3893258 CNV gain 25118596
nsv1066059 CNV gain 25217958
nsv1071953 CNV deletion 25765185
nsv1135860 CNV deletion 24896259
nsv1152353 CNV deletion 26484159
nsv7311 OTHER inversion 18451855
nsv961253 CNV duplication 23825009

Variation tolerance for ZNF814 Gene

Residual Variation Intolerance Score: 65.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.16; 39.22% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF814 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF814 Gene

Disorders for ZNF814 Gene

No disorders were found for ZNF814 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF814 Gene

Publications for ZNF814 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4
  3. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4
  4. Uncovering global SUMOylation signaling networks in a site-specific manner. (PMID: 25218447) Hendriks IA … Vertegaal AC (Nature structural & molecular biology 2014) 4
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for ZNF814 Gene

Sources for ZNF814 Gene