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Aliases for ZNF814 Gene

Aliases for ZNF814 Gene

  • Zinc Finger Protein 814 2 3 5
  • Putative Zinc Finger Protein LOC730051 4

External Ids for ZNF814 Gene

Previous GeneCards Identifiers for ZNF814 Gene

  • GC19U900727
  • GC19M063072
  • GC19M058380
  • GC19M054692
  • GC19M058361

Summaries for ZNF814 Gene

GeneCards Summary for ZNF814 Gene

ZNF814 (Zinc Finger Protein 814) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA binding transcription factor activity. An important paralog of this gene is ZNF841.

Additional gene information for ZNF814 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF814 Gene

Genomics for ZNF814 Gene

GeneHancer (GH) Regulatory Elements for ZNF814 Gene

Promoters and enhancers for ZNF814 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I057886 Promoter/Enhancer 2 EPDnew FANTOM5 Ensembl ENCODE 550.8 +0.8 816 2.8 CTCF PKNOX1 MXI1 USF1 MAX SIN3A KLF5 RAD21 ZBTB40 YY1 ZNF814 ZNF417 ZNF587 ZNF154 ZNF418 ZNF256 ZSCAN4 ZNF548 ZNF606 ZNF135
GH19I057890 Enhancer 0.2 ENCODE 550.8 -2.0 -1964 1.9 ZNF814 ZNF417 LOC100128398 ZNF587 ENSG00000269476
GH19I057769 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 19.1 +118.9 118850 2.4 PKNOX1 ATF1 SIN3A YY1 ETS1 POLR2B ZNF766 CBX5 ELK1 ZNF207 ZNF586 ZNF814 ZNF776 ZNF671 ZNF417 ZNF154 ZNF256 RPL19P19 ZSCAN4 ZNF419
GH19I057746 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 15.1 +142.0 141987 1.8 PKNOX1 ATF1 SMAD1 ZNF133 SIN3A GLI4 ZNF2 YY1 ETS1 POLR2B ZNF776 TRIM28 ZNF264 ZNF805 ZNF543 ZNF814 ZNF548 ZSCAN1 ZNF134 ZNF586
GH19I057801 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 18.9 +85.1 85140 5.3 CTCF KLF1 SMAD1 SAP130 ZNF384 POLR2A PRDM10 IKZF2 RUNX3 ZNF202 ENSG00000269867 ZNF587 TRIM28 ZNF324B ZNF814 ZNF264 ZNF417 ZNF550 ZNF543 ZNF548
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF814 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF814 gene promoter:

Genomic Locations for ZNF814 Gene

Genomic Locations for ZNF814 Gene
40,344 bases
Minus strand

Genomic View for ZNF814 Gene

Genes around ZNF814 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF814 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF814 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF814 Gene

Proteins for ZNF814 Gene

  • Protein details for ZNF814 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative uncharacterized zinc finger protein 814
    Protein Accession:
    Secondary Accessions:
    • A6NF35

    Protein attributes for ZNF814 Gene

    855 amino acids
    Molecular mass:
    97337 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF814 Gene

Post-translational modifications for ZNF814 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ZNF814 Gene

Domains & Families for ZNF814 Gene

Gene Families for ZNF814 Gene

Human Protein Atlas (HPA):
  • Cancer-related genes
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF814 Gene

Suggested Antigen Peptide Sequences for ZNF814 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZNF814: view

No data available for UniProtKB/Swiss-Prot for ZNF814 Gene

Function for ZNF814 Gene

Gene Ontology (GO) - Molecular Function for ZNF814 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF814: view

Animal Model Products

CRISPR Products

miRNA for ZNF814 Gene

miRTarBase miRNAs that target ZNF814

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF814 Gene

Localization for ZNF814 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF814 gene
Compartment Confidence
nucleus 3

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF814 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with ZNF814: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ZNF814 Gene

Pathways & Interactions for ZNF814 Gene

SuperPathways for ZNF814 Gene

No Data Available

Interacting Proteins for ZNF814 Gene

Gene Ontology (GO) - Biological Process for ZNF814 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0045892 negative regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF814: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF814 Gene

Drugs & Compounds for ZNF814 Gene

No Compound Related Data Available

Transcripts for ZNF814 Gene

mRNA/cDNA for ZNF814 Gene

(2) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(15) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF814 Gene

Zinc finger protein 814:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF814 Gene

No ASD Table

Relevant External Links for ZNF814 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF814 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF814 Gene

Protein differential expression in normal tissues from HIPED for ZNF814 Gene

This gene is overexpressed in Lung (57.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF814 Gene

Protein tissue co-expression partners for ZNF814 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF814 Gene:


SOURCE GeneReport for Unigene cluster for ZNF814 Gene:

genes like me logo Genes that share expression patterns with ZNF814: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF814 Gene

Orthologs for ZNF814 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF814 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF814 33
  • 96.45 (n)
(Canis familiaris)
Mammalia LOC102152013 33
  • 67.42 (n)
-- 34
  • 45 (a)
-- 34
  • 40 (a)
(Bos Taurus)
Mammalia ZNF154 33
  • 67.3 (n)
-- 34
  • 50 (a)
-- 34
  • 50 (a)
-- 34
  • 41 (a)
-- 34
  • 39 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 38 (a)
(Gallus gallus)
Aves ZNF814 34
  • 41 (a)
(Anolis carolinensis)
Reptilia ZNF814 34
  • 39 (a)
(Danio rerio)
Actinopterygii CU672268.1 34
  • 43 (a)
si:zfos-44a5.2 34
  • 43 (a)
AL954741.1 34
  • 42 (a)
BX640537.2 34
  • 41 (a)
CABZ01006831.1 34
  • 41 (a)
CABZ01075191.1 34
  • 41 (a)
si:ch211-235i11.2 34
  • 40 (a)
zgc:174712 34
  • 40 (a)
CABZ01006835.1 34
  • 38 (a)
CABZ01048402.1 34
  • 37 (a)
BX000701.1 34
  • 36 (a)
si:dkey-20i20.5 34
  • 36 (a)
zgc:113389 34
  • 36 (a)
FP326649.1 34
  • 35 (a)
Species where no ortholog for ZNF814 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF814 Gene

Gene Tree for ZNF814 (if available)
Gene Tree for ZNF814 (if available)

Paralogs for ZNF814 Gene

Paralogs for ZNF814 Gene

(532) SIMAP similar genes for ZNF814 Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with ZNF814: view

Variants for ZNF814 Gene

Sequence variations from dbSNP and Humsavar for ZNF814 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000045484 -- 57,869,547(-) T/C 3_prime_UTR_variant
rs1000131707 -- 57,881,215(-) C/T intron_variant
rs1000411453 -- 57,870,567(-) A/G 3_prime_UTR_variant
rs1000481179 -- 57,881,684(-) G/T intron_variant
rs1000675664 -- 57,871,589(-) A/G 3_prime_UTR_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF814 Gene

Variant ID Type Subtype PubMed ID
nsv961253 CNV duplication 23825009
nsv7311 OTHER inversion 18451855
nsv1152353 CNV deletion 26484159
nsv1135860 CNV deletion 24896259
nsv1071953 CNV deletion 25765185
nsv1066059 CNV gain 25217958
esv3893258 CNV gain 25118596
esv3644914 CNV loss 21293372
esv3644913 CNV gain 21293372
esv2763213 CNV gain 21179565
esv2719093 CNV deletion 23290073
esv2719092 CNV deletion 23290073
esv2302097 CNV deletion 18987734
esv1001775 CNV deletion 20482838
dgv3686n100 CNV gain 25217958

Variation tolerance for ZNF814 Gene

Residual Variation Intolerance Score: 65.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.16; 39.22% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF814 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF814 Gene

Disorders for ZNF814 Gene

Additional Disease Information for ZNF814

No disorders were found for ZNF814 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF814 Gene

Publications for ZNF814 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4 58
  3. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  4. Uncovering global SUMOylation signaling networks in a site-specific manner. (PMID: 25218447) Hendriks IA … Vertegaal AC (Nature structural & molecular biology 2014) 4 58
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58

Products for ZNF814 Gene

Sources for ZNF814 Gene

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