Aliases for ZNF813 Gene

Aliases for ZNF813 Gene

  • Zinc Finger Protein 813 2 3 4 5
  • FLJ16542 2
  • ZNF813 5

External Ids for ZNF813 Gene

Previous GeneCards Identifiers for ZNF813 Gene

  • GC19P058686
  • GC19P058664
  • GC19P053970
  • GC19P050291

Summaries for ZNF813 Gene

GeneCards Summary for ZNF813 Gene

ZNF813 (Zinc Finger Protein 813) is a Protein Coding gene. Diseases associated with ZNF813 include Cloacal Exstrophy. Among its related pathways are Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF888.

UniProtKB/Swiss-Prot Summary for ZNF813 Gene

Additional gene information for ZNF813 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF813 Gene

Genomics for ZNF813 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZNF813 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF813 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF813

Top Transcription factor binding sites by QIAGEN in the ZNF813 gene promoter:
  • Ik-1

Genomic Locations for ZNF813 Gene

Genomic Locations for ZNF813 Gene
chr19:53,467,733-53,496,255
(GRCh38/hg38)
Size:
28,523 bases
Orientation:
Plus strand
chr19:53,970,989-54,006,950
(GRCh37/hg19)
Size:
35,962 bases
Orientation:
Plus strand

Genomic View for ZNF813 Gene

Genes around ZNF813 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF813 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF813 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF813 Gene

Proteins for ZNF813 Gene

  • Protein details for ZNF813 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZN06-ZN813_HUMAN
    Recommended name:
    Zinc finger protein 813
    Protein Accession:
    Q6ZN06

    Protein attributes for ZNF813 Gene

    Size:
    617 amino acids
    Molecular mass:
    71721 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAD18569.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF813 Gene

Post-translational modifications for ZNF813 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF813 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF813 Gene

Domains & Families for ZNF813 Gene

Gene Families for ZNF813 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF813 Gene

Suggested Antigen Peptide Sequences for ZNF813 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 813 (ZN813_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q6ZN06

UniProtKB/Swiss-Prot:

ZN813_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF813: view

Function for ZNF813 Gene

Molecular function for ZNF813 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF813 Gene

Gene Ontology (GO) - Molecular Function for ZNF813 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF813: view
genes like me logo Genes that share phenotypes with ZNF813: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF813

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF813 Gene

Localization for ZNF813 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF813 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF813 gene
Compartment Confidence
nucleus 4
cytosol 2
cytoskeleton 1
mitochondrion 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF813 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF813: view

Pathways & Interactions for ZNF813 Gene

PathCards logo

SuperPathways for ZNF813 Gene

genes like me logo Genes that share pathways with ZNF813: view

Pathways by source for ZNF813 Gene

1 KEGG pathway for ZNF813 Gene

Gene Ontology (GO) - Biological Process for ZNF813 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF813: view

No data available for SIGNOR curated interactions for ZNF813 Gene

Drugs & Compounds for ZNF813 Gene

No Compound Related Data Available

Transcripts for ZNF813 Gene

mRNA/cDNA for ZNF813 Gene

1 REFSEQ mRNAs :
5 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF813

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF813 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b
SP1: -
SP2:
SP3: -

Relevant External Links for ZNF813 Gene

GeneLoc Exon Structure for
ZNF813

Expression for ZNF813 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF813 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF813 Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF813

SOURCE GeneReport for Unigene cluster for ZNF813 Gene:

Hs.710780

Evidence on tissue expression from TISSUES for ZNF813 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with ZNF813: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF813 Gene

Orthologs for ZNF813 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF813 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia -- 31
  • 100 (a)
ManyToMany
Dog
(Canis familiaris)
Mammalia -- 31
  • 54 (a)
ManyToMany
Cow
(Bos Taurus)
Mammalia -- 31
  • 42 (a)
ManyToMany
Species where no ortholog for ZNF813 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for ZNF813 Gene

ENSEMBL:
Gene Tree for ZNF813 (if available)
TreeFam:
Gene Tree for ZNF813 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF813: view image

Paralogs for ZNF813 Gene

(505) SIMAP similar genes for ZNF813 Gene using alignment to 3 proteins:

  • ZN813_HUMAN
  • C9JZ01_HUMAN
  • E7EU70_HUMAN

Pseudogenes.org Pseudogenes for ZNF813 Gene

genes like me logo Genes that share paralogs with ZNF813: view

Variants for ZNF813 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF813 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs10421308 - p.Arg231Lys
rs10422163 - p.Tyr439Phe
rs12460628 - p.Ile168Phe
rs12609217 - p.Asp93Val
rs2617667 - p.Ala62Thr

Additional dbSNP identifiers (rs#s) for ZNF813 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF813 Gene

Variant ID Type Subtype PubMed ID
dgv1071e212 CNV gain 25503493
dgv3648n100 CNV gain 25217958
dgv3649n100 CNV loss 25217958
dgv3650n100 CNV gain+loss 25217958
dgv3651n100 CNV gain 25217958
dgv3652n100 CNV gain 25217958
dgv431n27 CNV gain 19166990
dgv530e201 CNV deletion 23290073
dgv6536n54 CNV gain 21841781
dgv6537n54 CNV gain 21841781
dgv6539n54 CNV loss 21841781
dgv6540n54 CNV loss 21841781
dgv661e199 CNV deletion 23128226
dgv88e19 CNV loss 19470904
esv2491793 CNV deletion 19546169
esv2718812 CNV deletion 23290073
esv2718823 CNV deletion 23290073
esv2718824 CNV deletion 23290073
esv2758770 CNV loss 17122850
esv2762954 CNV gain+loss 21179565
esv3583517 CNV loss 25503493
esv3644756 CNV gain 21293372
esv3644757 CNV loss 21293372
esv3644758 CNV gain 21293372
esv3644760 CNV loss 21293372
esv3893241 CNV gain+loss 25118596
esv3893243 CNV gain 25118596
esv3893244 CNV gain 25118596
esv3893245 CNV loss 25118596
nsv1055497 CNV gain 25217958
nsv1055773 CNV gain 25217958
nsv1059834 CNV gain 25217958
nsv1072897 CNV deletion 25765185
nsv458779 CNV loss 19166990
nsv470156 CNV gain 18288195
nsv515728 CNV gain+loss 19592680
nsv580097 CNV gain+loss 21841781
nsv580101 CNV gain 21841781
nsv956579 CNV deletion 24416366
nsv963077 CNV duplication 23825009

Variation tolerance for ZNF813 Gene

Residual Variation Intolerance Score: 87% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.65; 86.36% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF813 Gene

Human Gene Mutation Database (HGMD)
ZNF813
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF813

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF813 Gene

Disorders for ZNF813 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZNF813 Gene - From: DISEASES

Disorder Aliases PubMed IDs
cloacal exstrophy
  • oeis complex
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for ZNF813

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with ZNF813: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF813 Gene

Publications for ZNF813 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  3. The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery. (PMID: 29180619) Kumar R … Vertegaal ACO (Nature communications 2017) 3
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for ZNF813 Gene

Sources for ZNF813 Gene