Aliases for ZNF81 Gene
External Ids for ZNF81 Gene
Previous HGNC Symbols for ZNF81 Gene
Previous GeneCards Identifiers for ZNF81 Gene
This gene encodes a protein that likely functions as a transcription factor. The protein contains an N-terminal KRAB domain and several C2H2-type zinc finger motifs. Mutations in this gene cause an X-linked form of intellectual disability (MRX45). Microduplication of a region of chromosome X including this gene has also been associated with other forms of intellectual disability. [provided by RefSeq, Jul 2017]
GeneCards Summary for ZNF81 Gene
ZNF81 (Zinc Finger Protein 81) is a Protein Coding gene. Diseases associated with ZNF81 include Non-Syndromic X-Linked Intellectual Disability and Syndromic X-Linked Intellectual Disability. Among its related pathways are Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity. An important paralog of this gene is ZNF41.
UniProtKB/Swiss-Prot Summary for ZNF81 Gene
May be involved in transcriptional regulation.