Aliases for ZNF81 Gene
External Ids for ZNF81 Gene
Previous HGNC Symbols for ZNF81 Gene
Previous GeneCards Identifiers for ZNF81 Gene
This gene encodes a protein that likely functions as a transcription factor. The protein contains an N-terminal KRAB domain and several C2H2-type zinc finger motifs. Mutations in this gene cause an X-linked form of intellectual disability (MRX45). Microduplication of a region of chromosome X including this gene has also been associated with other forms of intellectual disability. [provided by RefSeq, Jul 2017]
GeneCards Summary for ZNF81 Gene
ZNF81 (Zinc Finger Protein 81) is a Protein Coding gene. Diseases associated with ZNF81 include X-Linked Non-Specific Intellectual Disability and Aland Island Eye Disease. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA binding transcription factor activity. An important paralog of this gene is ZNF175.
UniProtKB/Swiss-Prot for ZNF81 Gene
May be involved in transcriptional regulation.