Aliases for ZNF808 Gene

Aliases for ZNF808 Gene

  • Zinc Finger Protein 808 2 3 4 5

External Ids for ZNF808 Gene

Previous GeneCards Identifiers for ZNF808 Gene

  • GC19P057722
  • GC19P057751
  • GC19P053030
  • GC19P049362

Summaries for ZNF808 Gene

GeneCards Summary for ZNF808 Gene

ZNF808 (Zinc Finger Protein 808) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity. An important paralog of this gene is ZNF721.

UniProtKB/Swiss-Prot Summary for ZNF808 Gene

Additional gene information for ZNF808 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF808 Gene

Genomics for ZNF808 Gene

GeneHancer (GH) Regulatory Elements for ZNF808 Gene

Promoters and enhancers for ZNF808 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF808 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF808

Genomic Locations for ZNF808 Gene

Genomic Locations for ZNF808 Gene
chr19:52,527,652-52,570,178
(GRCh38/hg38)
Size:
42,527 bases
Orientation:
Plus strand
chr19:53,030,905-53,067,717
(GRCh37/hg19)
Size:
36,813 bases
Orientation:
Plus strand

Genomic View for ZNF808 Gene

Genes around ZNF808 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF808 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF808 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF808 Gene

Proteins for ZNF808 Gene

  • Protein details for ZNF808 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N4W9-ZN808_HUMAN
    Recommended name:
    Zinc finger protein 808
    Protein Accession:
    Q8N4W9
    Secondary Accessions:
    • Q68CN7

    Protein attributes for ZNF808 Gene

    Size:
    903 amino acids
    Molecular mass:
    104825 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH33230.1; Type=Miscellaneous discrepancy; Note=In 3'-UTR.; Evidence={ECO:0000305}; Sequence=AAI30352.1; Type=Miscellaneous discrepancy; Note=In 3'-UTR.; Evidence={ECO:0000305}; Sequence=AAI30354.1; Type=Miscellaneous discrepancy; Note=In 3'-UTR.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF808 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF808 Gene

Post-translational modifications for ZNF808 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF808 Gene

Domains & Families for ZNF808 Gene

Gene Families for ZNF808 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF808 Gene

Blocks:
  • C2H2-type zinc finger signature
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF808 Gene

GenScript: Design optimal peptide antigens:
  • ZNF808 protein (C1K3N6_HUMAN)
  • ZNF808 protein (Q7Z749_HUMAN)
  • Zinc finger protein 808 (ZN808_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8N4W9

UniProtKB/Swiss-Prot:

ZN808_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF808: view

Function for ZNF808 Gene

Molecular function for ZNF808 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF808 Gene

Gene Ontology (GO) - Molecular Function for ZNF808 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IBA 21873635
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF808: view

Phenotypes for ZNF808 Gene

genes like me logo Genes that share phenotypes with ZNF808: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF808

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF808 Gene

Localization for ZNF808 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF808 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF808 gene
Compartment Confidence
nucleus 4

Gene Ontology (GO) - Cellular Components for ZNF808 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IBA 21873635
genes like me logo Genes that share ontologies with ZNF808: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF808 Gene

Pathways & Interactions for ZNF808 Gene

PathCards logo

SuperPathways for ZNF808 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF808 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF808: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF808 Gene

Drugs & Compounds for ZNF808 Gene

No Compound Related Data Available

Transcripts for ZNF808 Gene

mRNA/cDNA for ZNF808 Gene

4 REFSEQ mRNAs :
12 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF808

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF808 Gene

No ASD Table

Relevant External Links for ZNF808 Gene

GeneLoc Exon Structure for
ZNF808

Expression for ZNF808 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF808 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF808 Gene



Protein tissue co-expression partners for ZNF808 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF808

SOURCE GeneReport for Unigene cluster for ZNF808 Gene:

Hs.729294

Evidence on tissue expression from TISSUES for ZNF808 Gene

  • Eye(4.1)
genes like me logo Genes that share expression patterns with ZNF808: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF808 Gene

Orthologs for ZNF808 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF808 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF808 30
  • 98.53 (n)
mouse
(Mus musculus)
Mammalia Zfp51 31
  • 43 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 31
  • 40 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 48 (a)
ManyToMany
-- 31
  • 44 (a)
ManyToMany
-- 31
  • 42 (a)
ManyToMany
-- 31
  • 39 (a)
ManyToMany
CSA.1668 31
  • 36 (a)
ManyToMany
-- 31
  • 35 (a)
ManyToMany
Species where no ortholog for ZNF808 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF808 Gene

ENSEMBL:
Gene Tree for ZNF808 (if available)
TreeFam:
Gene Tree for ZNF808 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF808: view image

Paralogs for ZNF808 Gene

Paralogs for ZNF808 Gene

(665) SIMAP similar genes for ZNF808 Gene using alignment to 7 proteins:

  • ZN808_HUMAN
  • C1K3N6_HUMAN
  • C9IZE3_HUMAN
  • C9J0J5_HUMAN
  • C9J871_HUMAN
  • C9JVX0_HUMAN
  • Q7Z749_HUMAN

Pseudogenes.org Pseudogenes for ZNF808 Gene

genes like me logo Genes that share paralogs with ZNF808: view

Variants for ZNF808 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF808 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
778854 Benign: not provided 52,553,936(+) G/A SYNONYMOUS_VARIANT
778855 Benign: not provided 52,554,239(+) C/T SYNONYMOUS_VARIANT
784840 Benign: not provided 52,555,588(+) T/C MISSENSE_VARIANT
785643 Benign: not provided 52,553,318(+) G/C MISSENSE_VARIANT
rs329964 - p.Lys134Asn

Additional dbSNP identifiers (rs#s) for ZNF808 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF808 Gene

Variant ID Type Subtype PubMed ID
dgv3627n100 CNV gain 25217958
esv2718785 CNV deletion 23290073
esv2718786 CNV deletion 23290073
esv3893233 CNV loss 25118596
nsv1063648 CNV gain 25217958
nsv1065584 CNV loss 25217958
nsv1146332 OTHER inversion 26484159
nsv436854 CNV insertion 17901297
nsv510772 CNV deletion 20534489
nsv580026 CNV loss 21841781
nsv833874 CNV loss 17160897
nsv978841 CNV duplication 23825009

Variation tolerance for ZNF808 Gene

Residual Variation Intolerance Score: 71.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.84; 73.96% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF808 Gene

Human Gene Mutation Database (HGMD)
ZNF808
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF808

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF808 Gene

Disorders for ZNF808 Gene

Additional Disease Information for ZNF808

No disorders were found for ZNF808 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF808 Gene

Publications for ZNF808 Gene

  1. VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3 54
  2. The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery. (PMID: 29180619) Kumar R … Vertegaal ACO (Nature communications 2017) 3 54
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 54
  4. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 54
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 54

Products for ZNF808 Gene

Sources for ZNF808 Gene