Aliases for ZNF805 Gene

Aliases for ZNF805 Gene

  • Zinc Finger Protein 805 2 3 4 5
  • CTC-444N24.8 3
  • ZNF805 5

External Ids for ZNF805 Gene

Previous GeneCards Identifiers for ZNF805 Gene

  • GC19P062456
  • GC19P057752
  • GC19P054064

Summaries for ZNF805 Gene

GeneCards Summary for ZNF805 Gene

ZNF805 (Zinc Finger Protein 805) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF264.

UniProtKB/Swiss-Prot Summary for ZNF805 Gene

Additional gene information for ZNF805 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF805 Gene

Genomics for ZNF805 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZNF805 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF805 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF805

Top Transcription factor binding sites by QIAGEN in the ZNF805 gene promoter:
  • AML1a
  • FOXF2
  • GCNF
  • GCNF-1
  • GCNF-2
  • GR
  • GR-alpha
  • GR-beta
  • Hlf
  • STAT5A

Genomic Locations for ZNF805 Gene

Genomic Locations for ZNF805 Gene
chr19:57,240,632-57,262,728
(GRCh38/hg38)
Size:
22,097 bases
Orientation:
Plus strand
chr19:57,751,973-57,774,106
(GRCh37/hg19)
Size:
22,134 bases
Orientation:
Plus strand

Genomic View for ZNF805 Gene

Genes around ZNF805 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF805 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF805 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF805 Gene

Proteins for ZNF805 Gene

  • Protein details for ZNF805 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5CZA5-ZN805_HUMAN
    Recommended name:
    Zinc finger protein 805
    Protein Accession:
    Q5CZA5
    Secondary Accessions:
    • B4DNM5

    Protein attributes for ZNF805 Gene

    Size:
    627 amino acids
    Molecular mass:
    71143 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI56760.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
    Miscellaneous:
    • [Isoform 1]: Gene prediction based on similarity to orthologs.

    Alternative splice isoforms for ZNF805 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF805 Gene

Post-translational modifications for ZNF805 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF805 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF805 Gene

Domains & Families for ZNF805 Gene

Gene Families for ZNF805 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF805 Gene

Suggested Antigen Peptide Sequences for ZNF805 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 805 (B9EIQ3_HUMAN)
  • Zinc finger protein 805 (ZN805_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q5CZA5

UniProtKB/Swiss-Prot:

ZN805_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF805: view

Function for ZNF805 Gene

Molecular function for ZNF805 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF805 Gene

Gene Ontology (GO) - Molecular Function for ZNF805 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF805: view
genes like me logo Genes that share phenotypes with ZNF805: view

Animal Model Products

CRISPR Products

miRNA for ZNF805 Gene

miRTarBase miRNAs that target ZNF805

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF805

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF805 Gene

Localization for ZNF805 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF805 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF805 gene
Compartment Confidence
nucleus 4
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF805 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF805: view

Pathways & Interactions for ZNF805 Gene

PathCards logo

SuperPathways for ZNF805 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF805 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF805: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF805 Gene

Drugs & Compounds for ZNF805 Gene

No Compound Related Data Available

Transcripts for ZNF805 Gene

mRNA/cDNA for ZNF805 Gene

2 REFSEQ mRNAs :
4 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF805

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF805 Gene

No ASD Table

Relevant External Links for ZNF805 Gene

GeneLoc Exon Structure for
ZNF805

Expression for ZNF805 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF805 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

  • Heart (Cardiovascular System)

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF805

SOURCE GeneReport for Unigene cluster for ZNF805 Gene:

Hs.22488
genes like me logo Genes that share expression patterns with ZNF805: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF805 Gene

Orthologs for ZNF805 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF805 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ZNF805 30 31
  • 98.99 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia ZNF805 30
  • 86.46 (n)
Lizard
(Anolis carolinensis)
Reptilia -- 31
  • 41 (a)
OneToMany
Zebrafish
(Danio rerio)
Actinopterygii si:dkey-7j22.3 31
  • 51 (a)
ManyToMany
CU138542.3 31
  • 43 (a)
ManyToMany
Species where no ortholog for ZNF805 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for ZNF805 Gene

ENSEMBL:
Gene Tree for ZNF805 (if available)
TreeFam:
Gene Tree for ZNF805 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF805: view image

Paralogs for ZNF805 Gene

(529) SIMAP similar genes for ZNF805 Gene using alignment to 2 proteins:

  • ZN805_HUMAN
  • B9EIQ3_HUMAN
genes like me logo Genes that share paralogs with ZNF805: view

Variants for ZNF805 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF805 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs2014572 - p.Gly68Glu

Additional dbSNP identifiers (rs#s) for ZNF805 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF805 Gene

Variant ID Type Subtype PubMed ID
dgv547e201 CNV deletion 23290073
esv1942885 CNV deletion 18987734
esv22387 CNV loss 19812545
esv2719069 CNV deletion 23290073
esv3893256 CNV loss 25118596
nsv580400 CNV gain 21841781

Variation tolerance for ZNF805 Gene

Residual Variation Intolerance Score: 27.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.16; 84.71% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF805 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF805

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF805 Gene

Disorders for ZNF805 Gene

Additional Disease Information for ZNF805

No disorders were found for ZNF805 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF805 Gene

Publications for ZNF805 Gene

  1. Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. (PMID: 18821565) Lasky-Su J … Faraone SV (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008) 3 41
  2. Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis. (PMID: 30575818) Tiemann K … Kani K (Oncogene 2019) 3
  3. VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3
  5. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4

Products for ZNF805 Gene

Sources for ZNF805 Gene