Aliases for ZNF793 Gene

Aliases for ZNF793 Gene

  • Zinc Finger Protein 793 2 3 4 5

External Ids for ZNF793 Gene

Previous GeneCards Identifiers for ZNF793 Gene

  • GC19P042690
  • GC19P037997
  • GC19P034448

Summaries for ZNF793 Gene

GeneCards Summary for ZNF793 Gene

ZNF793 (Zinc Finger Protein 793) is a Protein Coding gene. Diseases associated with ZNF793 include Lung Cancer. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZSCAN20.

UniProtKB/Swiss-Prot Summary for ZNF793 Gene

Additional gene information for ZNF793 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF793 Gene

Genomics for ZNF793 Gene

GeneHancer (GH) Regulatory Elements for ZNF793 Gene

Promoters and enhancers for ZNF793 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF793 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF793

Top Transcription factor binding sites by QIAGEN in the ZNF793 gene promoter:
  • STAT5A
  • YY1

Genomic Locations for ZNF793 Gene

Genomic Locations for ZNF793 Gene
chr19:37,506,447-37,548,762
(GRCh38/hg38)
Size:
42,316 bases
Orientation:
Plus strand
chr19:37,997,841-38,039,664
(GRCh37/hg19)
Size:
41,824 bases
Orientation:
Plus strand

Genomic View for ZNF793 Gene

Genes around ZNF793 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF793 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF793 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF793 Gene

Proteins for ZNF793 Gene

  • Protein details for ZNF793 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZN11-ZN793_HUMAN
    Recommended name:
    Zinc finger protein 793
    Protein Accession:
    Q6ZN11
    Secondary Accessions:
    • E9PGN4
    • Q7Z3Q9

    Protein attributes for ZNF793 Gene

    Size:
    406 amino acids
    Molecular mass:
    46927 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAD97772.1; Type=Frameshift; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF793 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF793 Gene

Post-translational modifications for ZNF793 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF793 Gene

Domains & Families for ZNF793 Gene

Gene Families for ZNF793 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF793 Gene

Blocks:
  • KRAB box
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF793 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ61031, weakly similar to Zinc finger protein 569 (B4E1A1_HUMAN)
  • Zinc finger protein 793 (ZN793_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q6ZN11

UniProtKB/Swiss-Prot:

ZN793_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF793: view

Function for ZNF793 Gene

Molecular function for ZNF793 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF793 Gene

Gene Ontology (GO) - Molecular Function for ZNF793 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF793: view
genes like me logo Genes that share phenotypes with ZNF793: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF793

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF793 Gene

Localization for ZNF793 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF793 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF793 gene
Compartment Confidence
nucleus 4
cytosol 2
cytoskeleton 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoli (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF793 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF793: view

Pathways & Interactions for ZNF793 Gene

genes like me logo Genes that share pathways with ZNF793: view

Pathways by source for ZNF793 Gene

2 Reactome pathways for ZNF793 Gene
1 KEGG pathway for ZNF793 Gene

Interacting Proteins for ZNF793 Gene

;

Gene Ontology (GO) - Biological Process for ZNF793 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF793: view

No data available for SIGNOR curated interactions for ZNF793 Gene

Drugs & Compounds for ZNF793 Gene

No Compound Related Data Available

Transcripts for ZNF793 Gene

mRNA/cDNA for ZNF793 Gene

1 REFSEQ mRNAs :
7 NCBI additional mRNA sequence :
10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF793

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF793 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c
SP1:
SP2: -

Relevant External Links for ZNF793 Gene

GeneLoc Exon Structure for
ZNF793

Expression for ZNF793 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF793 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF793

SOURCE GeneReport for Unigene cluster for ZNF793 Gene:

Hs.568010

Evidence on tissue expression from TISSUES for ZNF793 Gene

  • Nervous system(4.1)
  • Eye(4)
genes like me logo Genes that share expression patterns with ZNF793: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF793 Gene

Orthologs for ZNF793 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF793 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF793 31 30
  • 99.01 (n)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF793 31 30
  • 87.18 (n)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF793 31
  • 87 (a)
OneToOne
Species where no ortholog for ZNF793 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF793 Gene

ENSEMBL:
Gene Tree for ZNF793 (if available)
TreeFam:
Gene Tree for ZNF793 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF793: view image

Paralogs for ZNF793 Gene

(456) SIMAP similar genes for ZNF793 Gene using alignment to 7 proteins:

  • ZN793_HUMAN
  • K7EL37_HUMAN
  • K7EMH8_HUMAN
  • K7EMU0_HUMAN
  • K7EN11_HUMAN
  • K7EQP3_HUMAN
  • K7ERJ7_HUMAN

Pseudogenes.org Pseudogenes for ZNF793 Gene

genes like me logo Genes that share paralogs with ZNF793: view

Variants for ZNF793 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF793 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs12977460 - p.Ile68Met
rs45593644 - p.Ile133Val

Additional dbSNP identifiers (rs#s) for ZNF793 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF793 Gene

Variant ID Type Subtype PubMed ID
esv2758759 CNV loss 17122850
esv3583375 CNV loss 25503493
esv3583376 CNV loss 25503493
esv3644288 CNV loss 21293372
nsv1056753 CNV loss 25217958
nsv2478 CNV deletion 18451855
nsv579468 CNV gain 21841781
nsv833819 CNV gain 17160897

Variation tolerance for ZNF793 Gene

Residual Variation Intolerance Score: 62.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.03; 50.17% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF793 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF793

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF793 Gene

Disorders for ZNF793 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZNF793 Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
lung cancer
  • adenocarcinoma of lung
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for ZNF793

genes like me logo Genes that share disorders with ZNF793: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF793 Gene

Publications for ZNF793 Gene

  1. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. (PMID: 28611215) Fei T … Brown M (Proceedings of the National Academy of Sciences of the United States of America 2017) 3 54
  2. Methylated B3GAT2 and ZNF793 Are Potential Detection Biomarkers for Barrett's Esophagus. (PMID: 26545406) Yu M … Grady WM (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2015) 3 54
  3. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 54
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 54
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 54

Products for ZNF793 Gene

Sources for ZNF793 Gene