Aliases for ZNF79 Gene

Aliases for ZNF79 Gene

  • Zinc Finger Protein 79 2 3 4 5
  • ZNFpT7 3 4
  • PT7 2 3
  • Zinc Finger Protein 79 (PT7) 2
  • ZNF79 5

External Ids for ZNF79 Gene

Previous GeneCards Identifiers for ZNF79 Gene

  • GC09P121301
  • GC09P121833
  • GC09P123640
  • GC09P125562
  • GC09P127266
  • GC09P129227
  • GC09P130186
  • GC09P099802

Summaries for ZNF79 Gene

GeneCards Summary for ZNF79 Gene

ZNF79 (Zinc Finger Protein 79) is a Protein Coding gene. Diseases associated with ZNF79 include Noonan Syndrome 7 and Prostate Carcinoma In Situ. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF570.

UniProtKB/Swiss-Prot Summary for ZNF79 Gene

Gene Wiki entry for ZNF79 Gene

Additional gene information for ZNF79 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF79 Gene

Genomics for ZNF79 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZNF79 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF79 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF79

Top Transcription factor binding sites by QIAGEN in the ZNF79 gene promoter:
  • AP-1
  • c-Myb
  • Elk-1
  • GATA-1
  • GATA-2
  • HTF
  • NCX
  • p53
  • PPAR-gamma1
  • PPAR-gamma2

Genomic Locations for ZNF79 Gene

Genomic Locations for ZNF79 Gene
chr9:127,424,374-127,446,289
(GRCh38/hg38)
Size:
21,916 bases
Orientation:
Plus strand
chr9:130,186,653-130,207,651
(GRCh37/hg19)
Size:
20,999 bases
Orientation:
Plus strand

Genomic View for ZNF79 Gene

Genes around ZNF79 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF79 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF79 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF79 Gene

Proteins for ZNF79 Gene

  • Protein details for ZNF79 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q15937-ZNF79_HUMAN
    Recommended name:
    Zinc finger protein 79
    Protein Accession:
    Q15937
    Secondary Accessions:
    • Q5VVW1
    • Q96NV1

    Protein attributes for ZNF79 Gene

    Size:
    498 amino acids
    Molecular mass:
    55350 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF79 Gene

Post-translational modifications for ZNF79 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF79 Gene

Domains & Families for ZNF79 Gene

Gene Families for ZNF79 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF79 Gene

InterPro:
Blocks:
  • C2H2-type zinc finger signature
  • KRAB box
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF79 Gene

GenScript: Design optimal peptide antigens:
  • ZNFpT7 (ZNF79_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q15937

UniProtKB/Swiss-Prot:

ZNF79_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF79: view

Function for ZNF79 Gene

Molecular function for ZNF79 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
GENATLAS Biochemistry:
zinc finger protein 79

Phenotypes From GWAS Catalog for ZNF79 Gene

Gene Ontology (GO) - Molecular Function for ZNF79 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0003700 DNA-binding transcription factor activity IBA 21873635
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with ZNF79: view
genes like me logo Genes that share phenotypes with ZNF79: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF79

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF79 Gene

Localization for ZNF79 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF79 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF79 gene
Compartment Confidence
nucleus 5
cytosol 4
plasma membrane 3
extracellular 2
cytoskeleton 2
mitochondrion 2
endoplasmic reticulum 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoplasm (2)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF79 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA 21873635
genes like me logo Genes that share ontologies with ZNF79: view

Pathways & Interactions for ZNF79 Gene

genes like me logo Genes that share pathways with ZNF79: view

Pathways by source for ZNF79 Gene

2 Reactome pathways for ZNF79 Gene
1 KEGG pathway for ZNF79 Gene

Gene Ontology (GO) - Biological Process for ZNF79 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ZNF79: view

No data available for SIGNOR curated interactions for ZNF79 Gene

Drugs & Compounds for ZNF79 Gene

No Compound Related Data Available

Transcripts for ZNF79 Gene

mRNA/cDNA for ZNF79 Gene

5 REFSEQ mRNAs :
10 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF79

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF79 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b
SP1: - - -
SP2: -
SP3: - - - -
SP4:

Relevant External Links for ZNF79 Gene

GeneLoc Exon Structure for
ZNF79

Expression for ZNF79 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF79 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF79 Gene



Protein tissue co-expression partners for ZNF79 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF79

SOURCE GeneReport for Unigene cluster for ZNF79 Gene:

Hs.522399

Evidence on tissue expression from TISSUES for ZNF79 Gene

  • Lung(4.4)
  • Skin(2.4)
  • Nervous system(2.4)
  • Kidney(2.3)
  • Blood(2.3)
  • Spleen(2)
genes like me logo Genes that share expression patterns with ZNF79: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF79 Gene

Orthologs for ZNF79 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF79 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ZNF79 30 31
  • 99.33 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia ZNF79 30 31
  • 85.34 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia ZNF79 30 31
  • 85.04 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia ZNF79 31
  • 64 (a)
OneToOne
Fruit Fly
(Drosophila melanogaster)
Insecta CG1832 32
  • 54 (a)
gl 32
  • 51 (a)
Kr 32
  • 50 (a)
CG9650 32
  • 48 (a)
BG:DS02740.8 32
  • 39 (a)
CG6654 31
  • 21 (a)
OneToMany
Species where no ortholog for ZNF79 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for ZNF79 Gene

ENSEMBL:
Gene Tree for ZNF79 (if available)
TreeFam:
Gene Tree for ZNF79 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF79: view image

Paralogs for ZNF79 Gene

(550) SIMAP similar genes for ZNF79 Gene using alignment to 2 proteins:

  • ZNF79_HUMAN
  • F5H032_HUMAN

Pseudogenes.org Pseudogenes for ZNF79 Gene

genes like me logo Genes that share paralogs with ZNF79: view

Variants for ZNF79 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF79 Gene

SNP ID Clinical significance and condition Chr 09 pos Variation AA Info Type
rs13292096 - p.Thr31Ile
rs3210752 - p.Ser401Asn
rs4504745 - p.Arg51Gly

Additional dbSNP identifiers (rs#s) for ZNF79 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF79 Gene

Variant ID Type Subtype PubMed ID
dgv1376e199 CNV deletion 23128226
esv1000498 CNV deletion 20482838
esv2665517 CNV deletion 23128226
esv3573391 CNV loss 25503493
esv3621782 CNV loss 21293372

Variation tolerance for ZNF79 Gene

Residual Variation Intolerance Score: 59.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.31; 26.05% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF79 Gene

Human Gene Mutation Database (HGMD)
ZNF79
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF79

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF79 Gene

Disorders for ZNF79 Gene

MalaCards: The human disease database

(2) MalaCards diseases for ZNF79 Gene - From: DISEASES

Disorder Aliases PubMed IDs
noonan syndrome 7
  • ns7
prostate carcinoma in situ
  • carcinoma in situ of prostate
- elite association - COSMIC cancer census association via MalaCards
Search ZNF79 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for ZNF79

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with ZNF79: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF79 Gene

Publications for ZNF79 Gene

  1. Chromosomal localization of four human zinc finger cDNAs. (PMID: 8478004) Huebner K … Pelicci PG (Human genetics 1993) 2 3 4
  2. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PMID: 19851296) Oguri M … Yamada Y (American journal of hypertension 2010) 3 41
  3. Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PMID: 20198315) Yoshida T … Yamada Y (International journal of molecular medicine 2010) 3 41
  4. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 3 4
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4

Products for ZNF79 Gene

Sources for ZNF79 Gene