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Aliases for ZNF789 Gene

Aliases for ZNF789 Gene

  • Zinc Finger Protein 789 2 3 5

External Ids for ZNF789 Gene

Previous GeneCards Identifiers for ZNF789 Gene

  • GC07P098908
  • GC07P099072
  • GC07P093707
  • GC07P099074
  • GC07P099078

Summaries for ZNF789 Gene

GeneCards Summary for ZNF789 Gene

ZNF789 (Zinc Finger Protein 789) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA binding transcription factor activity.

UniProtKB/Swiss-Prot for ZNF789 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF789 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF789 Gene

Genomics for ZNF789 Gene

GeneHancer (GH) Regulatory Elements for ZNF789 Gene

Promoters and enhancers for ZNF789 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I099471 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 569.8 -0.2 -225 3 HDGF PKNOX1 CLOCK FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF789 ZSCAN25 PPP1R35 PTCD1 MEPCE TRRAP STAG3L5P TRIM4 LOC101927550 AP4M1
GH07I100427 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 23.7 +960.4 960370 10.8 CLOCK ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 PPP1R35 MEPCE PIR54054 ZCWPW1 ZSCAN25 TRIM4 SRRT GIGYF1 ZNF3 PILRA
GH07I099579 Enhancer 1.3 FANTOM5 Ensembl ENCODE 35.9 +107.6 107572 1.2 ZNF529 ZNF2 ZBTB40 RAD21 ZNF335 ZNF213 ZNF354C ZNF366 ZNF202 ZNF680 ZSCAN25 TRRAP TRIM4 LOC100131859 ZNF3 ZNF655 ENSG00000242798 STAG3L5P AP4M1 LOC101927550
GH07I099557 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 11.2 +88.2 88157 7.9 ZFP64 DMAP1 YY1 E2F8 ZNF143 SP3 MEF2D SSRP1 GLIS1 NBN ZNF655 FAM200A ZSCAN25 ZNF3 TRIM4 PTCD1 LOC101927550 ZNF394 LOC100419643 TRRAP
GH07I100176 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 14.4 +704.6 704647 1.4 PKNOX1 CLOCK SIN3A YY1 ZNF335 EGR1 FOS ATF7 SP3 NFYA GPC2 STAG3 SRRT AP4M1 STAG3L5P GIGYF1 PVRIG MEPCE PTCD1 ENSG00000242798
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF789 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF789 gene promoter:

Genomic Locations for ZNF789 Gene

Genomic Locations for ZNF789 Gene
30,822 bases
Plus strand

Genomic View for ZNF789 Gene

Genes around ZNF789 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF789 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF789 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF789 Gene

Proteins for ZNF789 Gene

  • Protein details for ZNF789 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 789
    Protein Accession:
    Secondary Accessions:
    • A4D282
    • A6NH61
    • Q6ZMZ9

    Protein attributes for ZNF789 Gene

    425 amino acids
    Molecular mass:
    49984 Da
    Quaternary structure:
    No Data Available
    • Sequence=EAL23876.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF789 Gene


neXtProt entry for ZNF789 Gene

Post-translational modifications for ZNF789 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF789 Gene

Domains & Families for ZNF789 Gene

Gene Families for ZNF789 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF789 Gene

Suggested Antigen Peptide Sequences for ZNF789 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF789: view

Function for ZNF789 Gene

Molecular function for ZNF789 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF789 Gene

Gene Ontology (GO) - Molecular Function for ZNF789 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF789: view
genes like me logo Genes that share phenotypes with ZNF789: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF789 Gene

Localization for ZNF789 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF789 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF789 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF789 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with ZNF789: view

Pathways & Interactions for ZNF789 Gene

SuperPathways for ZNF789 Gene

No Data Available

Interacting Proteins for ZNF789 Gene

Gene Ontology (GO) - Biological Process for ZNF789 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF789: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF789 Gene

Drugs & Compounds for ZNF789 Gene

No Compound Related Data Available

Transcripts for ZNF789 Gene

Unigene Clusters for ZNF789 Gene

Zinc finger protein 789:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF789 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b
SP1: - - - -
SP2: -
SP3: - - - - -

Relevant External Links for ZNF789 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF789 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF789 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF789 Gene:


SOURCE GeneReport for Unigene cluster for ZNF789 Gene:


Evidence on tissue expression from TISSUES for ZNF789 Gene

  • Spleen(4.2)
genes like me logo Genes that share expression patterns with ZNF789: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF789 Gene

Orthologs for ZNF789 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF789 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF789 33 34
  • 99.53 (n)
(Canis familiaris)
Mammalia ZNF789 33 34
  • 81.75 (n)
(Bos Taurus)
Mammalia ZNF789 33 34
  • 80 (n)
Species where no ortholog for ZNF789 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF789 Gene

Gene Tree for ZNF789 (if available)
Gene Tree for ZNF789 (if available)

Paralogs for ZNF789 Gene

(429) SIMAP similar genes for ZNF789 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF789: view

No data available for Paralogs for ZNF789 Gene

Variants for ZNF789 Gene

Sequence variations from dbSNP and Humsavar for ZNF789 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000117569 -- 99,474,332(+) C/A/G genic_upstream_transcript_variant, intron_variant
rs1000352984 -- 99,483,456(+) C/T 5_prime_UTR_variant, genic_downstream_transcript_variant, intron_variant
rs1000357490 -- 99,484,904(+) G/A genic_downstream_transcript_variant, intron_variant
rs1000466105 -- 99,477,714(+) GGGGGG/GGGGG genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000541800 -- 99,472,230(+) T/A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF789 Gene

Variant ID Type Subtype PubMed ID
esv3576408 CNV gain 25503493
esv3614278 CNV loss 21293372
nsv831069 CNV loss 17160897

Variation tolerance for ZNF789 Gene

Residual Variation Intolerance Score: 55.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.38; 90.85% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF789 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF789 Gene

Disorders for ZNF789 Gene

Additional Disease Information for ZNF789

No disorders were found for ZNF789 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF789 Gene

Publications for ZNF789 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer SW … Tsui LC (Science (New York, N.Y.) 2003) 3 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  4. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PMID: 16712791) Wang AG … Kim NS (Biochemical and biophysical research communications 2006) 3 58
  5. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh JH … Kim NS (Mammalian genome : official journal of the International Mammalian Genome Society 2005) 3 58

Products for ZNF789 Gene

Sources for ZNF789 Gene

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