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Aliases for ZNF783 Gene

Aliases for ZNF783 Gene

  • Zinc Finger Family Member 783 2 3 5
  • Protein ZNF783 3

External Ids for ZNF783 Gene

Previous GeneCards Identifiers for ZNF783 Gene

  • GC07P148590
  • GC07P148959

Summaries for ZNF783 Gene

GeneCards Summary for ZNF783 Gene

ZNF783 (Zinc Finger Family Member 783) is a Protein Coding gene. Diseases associated with ZNF783 include Acrodysostosis. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and transcription coregulator activity. An important paralog of this gene is ZNF746.

UniProtKB/Swiss-Prot for ZNF783 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF783 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF783 Gene

Genomics for ZNF783 Gene

GeneHancer (GH) Regulatory Elements for ZNF783 Gene

Promoters and enhancers for ZNF783 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J149261 Promoter/Enhancer 1.5 Ensembl ENCODE 697 0.0 -26 2 SMAD1 MLX ARNT ARID4B SIN3A FEZF1 DMAP1 YY1 ZNF207 ZNF143 ZNF783 ENSG00000271664 ZNF212 LOC155060 ZNF767P ZNF398 ZNF282 ZNF777 PIR51256
GH07J149143 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 66.1 -115.6 -115647 7 HDGF PKNOX1 SMAD1 ARNT ARID4B NEUROD1 SIN3A ZNF2 YY1 POLR2B ZNF398 ZNF425 GC07P149147 GC07P149148 ZNF783 ZNF282 ZNF212 ENSG00000271664 LOC155060 ZNF767P
GH07J149124 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 78.5 -135.3 -135345 3.8 CLOCK MLX DMAP1 YY1 ZNF213 E2F8 ZNF143 SP3 NFYC ZFP41 ZNF398 ZNF425 GC07M149126 RN7SL521P ZNF786 ZNF212 ZNF783 ENSG00000271664 ZNF282 ZNF767P
GH07J148940 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE 68.9 -320.8 -320770 2.8 PKNOX1 SMAD1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B EZH2 GC07P148942 RNY5 ZNF398 ZNF783 ZNF777 ENSG00000271664 ZNF212 ZNF767P LOC155060
GH07J148882 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 52.6 -378.3 -378324 3.6 HNRNPUL1 PKNOX1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B EZH2 GC07P148885 ZNF783 ZNF398 ENSG00000271664 ZNF212 ZNF282 ZNF767P LOC155060 ZNF777
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF783 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF783 gene promoter:
  • Nkx2-5
  • CP2
  • AREB6
  • LyF-1
  • E47
  • Hand1
  • Tal-1
  • GATA-1
  • MyoD

Genomic Locations for ZNF783 Gene

Genomic Locations for ZNF783 Gene
35,132 bases
Plus strand
35,132 bases
Plus strand

Genomic View for ZNF783 Gene

Genes around ZNF783 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF783 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF783 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF783 Gene

Proteins for ZNF783 Gene

  • Protein details for ZNF783 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein ZNF783
    Protein Accession:
    Secondary Accessions:
    • C9J9J2

    Protein attributes for ZNF783 Gene

    281 amino acids
    Molecular mass:
    31422 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF783 Gene


neXtProt entry for ZNF783 Gene

Post-translational modifications for ZNF783 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF783 Gene

No data available for DME Specific Peptides for ZNF783 Gene

Domains & Families for ZNF783 Gene

Gene Families for ZNF783 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF783 Gene


Suggested Antigen Peptide Sequences for ZNF783 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZNF783: view

No data available for UniProtKB/Swiss-Prot for ZNF783 Gene

Function for ZNF783 Gene

Molecular function for ZNF783 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF783 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0042802 identical protein binding IPI 25416956
genes like me logo Genes that share ontologies with ZNF783: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF783 Gene

Localization for ZNF783 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF783 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF783 gene
Compartment Confidence
nucleus 5
plasma membrane 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF783 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF783: view

Pathways & Interactions for ZNF783 Gene

SuperPathways for ZNF783 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF783 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF783: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF783 Gene

Drugs & Compounds for ZNF783 Gene

No Compound Related Data Available

Transcripts for ZNF783 Gene

mRNA/cDNA for ZNF783 Gene

(2) REFSEQ mRNAs :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF783 Gene

No ASD Table

Relevant External Links for ZNF783 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF783 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF783 Gene

Protein differential expression in normal tissues from HIPED for ZNF783 Gene

This gene is overexpressed in Neutrophil (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF783 Gene

Protein tissue co-expression partners for ZNF783 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF783 Gene:


Evidence on tissue expression from TISSUES for ZNF783 Gene

  • Nervous system(3.3)
genes like me logo Genes that share expression patterns with ZNF783: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF783 Gene

Orthologs for ZNF783 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF783 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF783 34 33
  • 98.53 (n)
(Bos Taurus)
Mammalia ZNF783 34 33
  • 84.14 (n)
(Canis familiaris)
Mammalia ZNF783 34 33
  • 83.55 (n)
(Monodelphis domestica)
Mammalia -- 34
  • 34 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 33 (a)
(Mus musculus)
Mammalia Zfp956 34
  • 29 (a)
(Gallus gallus)
Aves -- 34
  • 25 (a)
Species where no ortholog for ZNF783 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF783 Gene

Gene Tree for ZNF783 (if available)
Gene Tree for ZNF783 (if available)
Evolutionary constrained regions (ECRs) for ZNF783: view image

Paralogs for ZNF783 Gene

Paralogs for ZNF783 Gene

genes like me logo Genes that share paralogs with ZNF783: view

Variants for ZNF783 Gene

Sequence variations from dbSNP and Humsavar for ZNF783 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000032478 -- 149,276,958(+) C/T intron_variant
rs1000132327 -- 149,265,279(+) A/G intron_variant
rs1000216556 -- 149,274,763(+) T/A intron_variant
rs1000249337 -- 149,274,489(+) C/A intron_variant
rs1000302203 -- 149,284,990(+) G/A 3_prime_UTR_variant, genic_downstream_transcript_variant, non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF783 Gene

Variant ID Type Subtype PubMed ID
nsv1024700 CNV loss 25217958
nsv1126814 CNV deletion 24896259
nsv473100 CNV novel sequence insertion 20440878
nsv6001 CNV deletion 18451855

Variation tolerance for ZNF783 Gene

Residual Variation Intolerance Score: 67.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.74; 66.40% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF783 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF783 Gene

Disorders for ZNF783 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZNF783 Gene - From: HGMD and GeneCards

Disorder Aliases PubMed IDs
  • acrodysplasia
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for ZNF783

genes like me logo Genes that share disorders with ZNF783: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF783 Gene

Publications for ZNF783 Gene

  1. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PMID: 19413330) Gauci S … Mohammed S (Analytical chemistry 2009) 3 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  3. Large-scale concatenation cDNA sequencing. (PMID: 9110174) Yu W … Gibbs RA (Genome research 1997) 2 3 58
  4. A "double adaptor" method for improved shotgun library construction. (PMID: 8619474) Andersson B … Gibbs RA (Analytical biochemistry 1996) 2 3 58
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58

Products for ZNF783 Gene

Sources for ZNF783 Gene

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