Aliases for ZNF783 Gene

Aliases for ZNF783 Gene

  • Zinc Finger Family Member 783 2 3 5
  • Protein ZNF783 3 4
  • DKFZp667J212 2
  • ZNF783 5

External Ids for ZNF783 Gene

Previous GeneCards Identifiers for ZNF783 Gene

  • GC07P148590
  • GC07P148959

Summaries for ZNF783 Gene

GeneCards Summary for ZNF783 Gene

ZNF783 (Zinc Finger Family Member 783) is a Protein Coding gene. Diseases associated with ZNF783 include Acrodysostosis. Among its related pathways are Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and transcription coregulator activity. An important paralog of this gene is ZNF212.

UniProtKB/Swiss-Prot Summary for ZNF783 Gene

Additional gene information for ZNF783 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF783 Gene

Genomics for ZNF783 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZNF783 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF783 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF783

Top Transcription factor binding sites by QIAGEN in the ZNF783 gene promoter:
  • AREB6
  • CP2
  • E47
  • GATA-1
  • Hand1
  • LyF-1
  • MyoD
  • Nkx2-5
  • Tal-1

Genomic Locations for ZNF783 Gene

Genomic Locations for ZNF783 Gene
chr7:149,262,171-149,297,302
(GRCh38/hg38)
Size:
35,132 bases
Orientation:
Plus strand
chr7:148,959,262-148,994,393
(GRCh37/hg19)
Size:
35,132 bases
Orientation:
Plus strand

Genomic View for ZNF783 Gene

Genes around ZNF783 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF783 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF783 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF783 Gene

Proteins for ZNF783 Gene

  • Protein details for ZNF783 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZMS7-ZN783_HUMAN
    Recommended name:
    Protein ZNF783
    Protein Accession:
    Q6ZMS7
    Secondary Accessions:
    • C9J9J2

    Protein attributes for ZNF783 Gene

    Size:
    281 amino acids
    Molecular mass:
    31422 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF783 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF783 Gene

Post-translational modifications for ZNF783 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF783 Gene

No data available for DME Specific Peptides for ZNF783 Gene

Domains & Families for ZNF783 Gene

Gene Families for ZNF783 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF783 Gene

InterPro:
Blocks:
  • KRAB box
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF783 Gene

GenScript: Design optimal peptide antigens:
  • Protein ZNF783 (ZN783_HUMAN)
genes like me logo Genes that share domains with ZNF783: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ZNF783 Gene

Function for ZNF783 Gene

Molecular function for ZNF783 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF783 Gene

Gene Ontology (GO) - Molecular Function for ZNF783 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with ZNF783: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF783

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF783 Gene

Localization for ZNF783 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF783 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF783 gene
Compartment Confidence
nucleus 4
plasma membrane 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF783 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF783: view

Pathways & Interactions for ZNF783 Gene

PathCards logo

SuperPathways for ZNF783 Gene

genes like me logo Genes that share pathways with ZNF783: view

Pathways by source for ZNF783 Gene

1 KEGG pathway for ZNF783 Gene

Gene Ontology (GO) - Biological Process for ZNF783 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF783: view

No data available for SIGNOR curated interactions for ZNF783 Gene

Drugs & Compounds for ZNF783 Gene

No Compound Related Data Available

Transcripts for ZNF783 Gene

mRNA/cDNA for ZNF783 Gene

1 REFSEQ mRNAs :
4 NCBI additional mRNA sequence :
5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF783

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF783 Gene

No ASD Table

Relevant External Links for ZNF783 Gene

GeneLoc Exon Structure for
ZNF783

Expression for ZNF783 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF783 Gene

Protein differential expression in normal tissues from HIPED for ZNF783 Gene

This gene is overexpressed in Neutrophil (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF783 Gene



Protein tissue co-expression partners for ZNF783 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF783

Evidence on tissue expression from TISSUES for ZNF783 Gene

  • Nervous system(3.3)
genes like me logo Genes that share expression patterns with ZNF783: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF783 Gene

Orthologs for ZNF783 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF783 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ZNF783 30 31
  • 98.53 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia ZNF783 30 31
  • 84.14 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia ZNF783 30 31
  • 83.55 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 34 (a)
ManyToMany
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 33 (a)
ManyToMany
Mouse
(Mus musculus)
Mammalia Zfp956 31
  • 29 (a)
ManyToMany
Chicken
(Gallus gallus)
Aves -- 31
  • 25 (a)
ManyToMany
Species where no ortholog for ZNF783 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for ZNF783 Gene

ENSEMBL:
Gene Tree for ZNF783 (if available)
TreeFam:
Gene Tree for ZNF783 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF783: view image

Paralogs for ZNF783 Gene

Paralogs for ZNF783 Gene

genes like me logo Genes that share paralogs with ZNF783: view

Variants for ZNF783 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF783 Gene

SNP ID Clinical significance and condition Chr 07 pos Variation AA Info Type
rs764239191 - p.Arg63Cys

Additional dbSNP identifiers (rs#s) for ZNF783 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF783 Gene

Variant ID Type Subtype PubMed ID
nsv1024700 CNV loss 25217958
nsv1126814 CNV deletion 24896259
nsv473100 CNV novel sequence insertion 20440878
nsv6001 CNV deletion 18451855

Variation tolerance for ZNF783 Gene

Residual Variation Intolerance Score: 67.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.74; 66.40% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF783 Gene

Human Gene Mutation Database (HGMD)
ZNF783
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF783

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF783 Gene

Disorders for ZNF783 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZNF783 Gene - From: GeneCards

Disorder Aliases PubMed IDs
acrodysostosis
  • acrodysplasia
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with ZNF783: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF783 Gene

Publications for ZNF783 Gene

  1. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PMID: 19413330) Gauci S … Mohammed S (Analytical chemistry 2009) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  3. Large-scale concatenation cDNA sequencing. (PMID: 9110174) Yu W … Gibbs RA (Genome research 1997) 2 3
  4. A "double adaptor" method for improved shotgun library construction. (PMID: 8619474) Andersson B … Gibbs RA (Analytical biochemistry 1996) 2 3
  5. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3

Products for ZNF783 Gene

Sources for ZNF783 Gene