Aliases for ZNF782 Gene

Aliases for ZNF782 Gene

  • Zinc Finger Protein 782 2 3 4 5

External Ids for ZNF782 Gene

Previous GeneCards Identifiers for ZNF782 Gene

  • GC09M098619
  • GC09M099578
  • GC09M069190

Summaries for ZNF782 Gene

GeneCards Summary for ZNF782 Gene

ZNF782 (Zinc Finger Protein 782) is a Protein Coding gene. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity. An important paralog of this gene is ZNF658.

UniProtKB/Swiss-Prot Summary for ZNF782 Gene

Additional gene information for ZNF782 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF782 Gene

Genomics for ZNF782 Gene

GeneHancer (GH) Regulatory Elements for ZNF782 Gene

Promoters and enhancers for ZNF782 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF782 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF782

Top Transcription factor binding sites by QIAGEN in the ZNF782 gene promoter:
  • Evi-1
  • FOXI1
  • FOXO1
  • FOXO1a
  • HFH-3
  • Nkx6-1
  • POU2F1a
  • POU3F2
  • POU3F2 (N-Oct-5a)
  • POU3F2 (N-Oct-5b)

Genomic Locations for ZNF782 Gene

Genomic Locations for ZNF782 Gene
chr9:96,816,269-97,013,673
(GRCh38/hg38)
Size:
197,405 bases
Orientation:
Minus strand
chr9:99,578,754-99,637,905
(GRCh37/hg19)
Size:
59,152 bases
Orientation:
Minus strand

Genomic View for ZNF782 Gene

Genes around ZNF782 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF782 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF782 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF782 Gene

Proteins for ZNF782 Gene

  • Protein details for ZNF782 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZMW2-ZN782_HUMAN
    Recommended name:
    Zinc finger protein 782
    Protein Accession:
    Q6ZMW2
    Secondary Accessions:
    • B2RNR0

    Protein attributes for ZNF782 Gene

    Size:
    699 amino acids
    Molecular mass:
    80904 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF782 Gene

Post-translational modifications for ZNF782 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF782 Gene

Domains & Families for ZNF782 Gene

Gene Families for ZNF782 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF782 Gene

Blocks:
  • C2H2-type zinc finger signature
  • KRAB box
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF782 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 782 (ZN782_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q6ZMW2

UniProtKB/Swiss-Prot:

ZN782_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF782: view

Function for ZNF782 Gene

Molecular function for ZNF782 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF782 Gene

Gene Ontology (GO) - Molecular Function for ZNF782 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF782: view
genes like me logo Genes that share phenotypes with ZNF782: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF782 Gene

Localization for ZNF782 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF782 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF782 gene
Compartment Confidence
nucleus 4
mitochondrion 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Mitochondria (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF782 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF782: view

Pathways & Interactions for ZNF782 Gene

genes like me logo Genes that share pathways with ZNF782: view

Pathways by source for ZNF782 Gene

2 Reactome pathways for ZNF782 Gene
1 KEGG pathway for ZNF782 Gene

Interacting Proteins for ZNF782 Gene

;

Gene Ontology (GO) - Biological Process for ZNF782 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF782: view

No data available for SIGNOR curated interactions for ZNF782 Gene

Drugs & Compounds for ZNF782 Gene

No Compound Related Data Available

Transcripts for ZNF782 Gene

mRNA/cDNA for ZNF782 Gene

4 REFSEQ mRNAs :
6 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF782 Gene

No ASD Table

Relevant External Links for ZNF782 Gene

GeneLoc Exon Structure for
ZNF782

Expression for ZNF782 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF782 Gene

Protein differential expression in normal tissues from HIPED for ZNF782 Gene

This gene is overexpressed in Plasma (63.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF782 Gene



Protein tissue co-expression partners for ZNF782 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF782

SOURCE GeneReport for Unigene cluster for ZNF782 Gene:

Hs.732126

Evidence on tissue expression from TISSUES for ZNF782 Gene

  • Lung(4.2)
genes like me logo Genes that share expression patterns with ZNF782: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF782 Gene

Orthologs for ZNF782 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF782 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF782 31 30
  • 99.57 (n)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF782 31 30
  • 86.19 (n)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF782 31 30
  • 85.65 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp300 31
  • 44 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 31
  • 32 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC496795 30
  • 55.04 (n)
Species where no ortholog for ZNF782 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF782 Gene

ENSEMBL:
Gene Tree for ZNF782 (if available)
TreeFam:
Gene Tree for ZNF782 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF782: view image

Paralogs for ZNF782 Gene

Paralogs for ZNF782 Gene

(543) SIMAP similar genes for ZNF782 Gene using alignment to 5 proteins:

  • ZN782_HUMAN
  • C9J9Y8_HUMAN
  • F8WEU9_HUMAN
  • G3V1K9_HUMAN
  • H0Y892_HUMAN
genes like me logo Genes that share paralogs with ZNF782: view

Variants for ZNF782 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF782 Gene

SNP ID Clinical significance and condition Chr 09 pos Variation AA Info Type
rs34763627 - p.Asn246Ser
rs35403084 - p.Thr289Ala
rs4645656 - p.Arg165His
rs7870376 - p.Arg130Pro

Additional dbSNP identifiers (rs#s) for ZNF782 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF782 Gene

Variant ID Type Subtype PubMed ID
esv2668332 CNV deletion 23128226
esv3621174 CNV loss 21293372
nsv1147999 OTHER inversion 26484159
nsv473484 CNV novel sequence insertion 20440878
nsv475931 CNV novel sequence insertion 20440878
nsv520001 CNV loss 19592680
nsv6624 CNV deletion 18451855
nsv831660 CNV gain 17160897
nsv831661 CNV loss 17160897

Variation tolerance for ZNF782 Gene

Residual Variation Intolerance Score: 91% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.60; 65.33% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF782 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF782

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF782 Gene

Disorders for ZNF782 Gene

Additional Disease Information for ZNF782

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for ZNF782 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF782 Gene

Publications for ZNF782 Gene

  1. Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci. (PMID: 19030899) Lei SF … Deng HW (Human genetics 2009) 3 41 54
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 54
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L … Andersson-Svahn H (Molecular & cellular proteomics : MCP 2008) 3 54
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 54

Products for ZNF782 Gene

Sources for ZNF782 Gene