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Aliases for ZNF781 Gene

Aliases for ZNF781 Gene

  • Zinc Finger Protein 781 2 3 5

External Ids for ZNF781 Gene

Previous GeneCards Identifiers for ZNF781 Gene

  • GC19M042851
  • GC19M038158
  • GC19M034608

Summaries for ZNF781 Gene

GeneCards Summary for ZNF781 Gene

ZNF781 (Zinc Finger Protein 781) is a Protein Coding gene.

UniProtKB/Swiss-Prot for ZNF781 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF781 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF781 Gene

Genomics for ZNF781 Gene

GeneHancer (GH) Regulatory Elements for ZNF781 Gene

Promoters and enhancers for ZNF781 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I037691 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 550.8 +0.2 210 1.5 PKNOX1 ATF1 ARID4B SIN3A DMAP1 ZNF48 YY1 ZNF143 ATF7 NFYC ZFP30 GC19M038813 SELENOKP1 ZNF781 LINC01535 ZNF607 ENSG00000267552 PIR37882
GH19I037593 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 111 +97.6 97621 2.2 PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 IRF4 YY1 SLC30A9 ZNF213 ZNF571 ZNF540 ZNF567 ZNF527 ZFP30 ZNF383 HKR1 ZNF345 ZNF585A ZNF607
GH19I038647 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 83.5 -967.5 -967471 25.6 ZFP64 FEZF1 DMAP1 YY1 ZNF213 ZNF143 ZNF548 SP3 NFYC ZC3H11A ACTN4 HNRNPL ZFP30 ZNF607 ZNF781 ZNF573 SUPT5H ENSG00000267152 PAK4 RN7SL566P
GH19I037778 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 86 -87.1 -87141 2.3 PKNOX1 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B IRF4 YY1 POLR2B ZNF766 ZNF573 LOC728533 ZNF345 ZNF383 ZFP30 ZNF527 ZNF585B ZNF790 ZNF781 ZNF571
GH19I037653 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 82.3 +37.0 37022 3 MLX ZFP64 FEZF1 DMAP1 YY1 ZNF213 ZNF416 ZNF143 ZNF548 SP3 ZFP30 ZNF527 ZNF567 ZNF383 ZNF345 ZNF571 ZNF790 HKR1 ZNF850 ZNF585A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF781 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF781 gene promoter:

Genomic Locations for ZNF781 Gene

Genomic Locations for ZNF781 Gene
chr19:37,667,749-37,692,322
(GRCh38/hg38)
Size:
24,574 bases
Orientation:
Minus strand
chr19:38,158,650-38,183,223
(GRCh37/hg19)

Genomic View for ZNF781 Gene

Genes around ZNF781 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF781 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF781 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF781 Gene

Proteins for ZNF781 Gene

  • Protein details for ZNF781 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N8C0-ZN781_HUMAN
    Recommended name:
    Zinc finger protein 781
    Protein Accession:
    Q8N8C0
    Secondary Accessions:
    • Q2VPJ8

    Protein attributes for ZNF781 Gene

    Size:
    355 amino acids
    Molecular mass:
    41526 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF781 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF781 Gene

Post-translational modifications for ZNF781 Gene

No Post-translational modifications

Other Protein References for ZNF781 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF781 Gene

Domains & Families for ZNF781 Gene

Gene Families for ZNF781 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF781 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF781 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N8C0

UniProtKB/Swiss-Prot:

ZN781_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF781: view

Function for ZNF781 Gene

Molecular function for ZNF781 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF781 Gene

Gene Ontology (GO) - Molecular Function for ZNF781 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF781: view
genes like me logo Genes that share phenotypes with ZNF781: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF781 Gene

Localization for ZNF781 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF781 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF781 gene
Compartment Confidence
nucleus 5
mitochondrion 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF781 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF781: view

Pathways & Interactions for ZNF781 Gene

SuperPathways for ZNF781 Gene

No Data Available

Interacting Proteins for ZNF781 Gene

Gene Ontology (GO) - Biological Process for ZNF781 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF781: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF781 Gene

Drugs & Compounds for ZNF781 Gene

No Compound Related Data Available

Transcripts for ZNF781 Gene

Unigene Clusters for ZNF781 Gene

Zinc finger protein 781:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF781 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7
SP1: -
SP2: - -
SP3: - -
SP4: -
SP5: - - - - -

Relevant External Links for ZNF781 Gene

GeneLoc Exon Structure for
ZNF781
ECgene alternative splicing isoforms for
ZNF781

Expression for ZNF781 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF781 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF781 Gene



NURSA nuclear receptor signaling pathways regulating expression of ZNF781 Gene:

ZNF781

SOURCE GeneReport for Unigene cluster for ZNF781 Gene:

Hs.722657

Evidence on tissue expression from TISSUES for ZNF781 Gene

  • Intestine(4.1)
  • Skin(4)
genes like me logo Genes that share expression patterns with ZNF781: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF781 Gene

Orthologs for ZNF781 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF781 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia ZNF781 34
  • 39 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm3055 34
  • 18 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia ZNF781 34
  • 15 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 24 (a)
OneToMany
-- 34
  • 22 (a)
OneToMany
-- 34
  • 13 (a)
OneToMany
Species where no ortholog for ZNF781 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF781 Gene

ENSEMBL:
Gene Tree for ZNF781 (if available)
TreeFam:
Gene Tree for ZNF781 (if available)

Paralogs for ZNF781 Gene

Pseudogenes.org Pseudogenes for ZNF781 Gene

genes like me logo Genes that share paralogs with ZNF781: view

No data available for Paralogs for ZNF781 Gene

Variants for ZNF781 Gene

Sequence variations from dbSNP and Humsavar for ZNF781 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000186256 -- 37,688,106(-) C/T intron_variant
rs1000555544 -- 37,674,575(-) A/T intron_variant
rs1000608016 -- 37,674,273(-) A/G intron_variant
rs1000754577 -- 37,693,043(-) A/G upstream_transcript_variant
rs1000791746 -- 37,689,696(-) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF781 Gene

Variant ID Type Subtype PubMed ID
nsv579468 CNV gain 21841781
esv3644291 CNV loss 21293372
esv3644290 CNV loss 21293372

Variation tolerance for ZNF781 Gene

Residual Variation Intolerance Score: 50.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.86; 58.91% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF781 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF781

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF781 Gene

Disorders for ZNF781 Gene

Additional Disease Information for ZNF781

No disorders were found for ZNF781 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF781 Gene

Publications for ZNF781 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for ZNF781 Gene

Sources for ZNF781 Gene

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