Aliases for ZNF780B Gene

Aliases for ZNF780B Gene

  • Zinc Finger Protein 780B 2 3 4 5
  • Zinc Finger Protein 779 2 3 4
  • ZNF779 3 4

External Ids for ZNF780B Gene

Previous HGNC Symbols for ZNF780B Gene

  • ZNF779

Previous GeneCards Identifiers for ZNF780B Gene

  • GC19M045232
  • GC19M040534
  • GC19M036971
  • GC19M040029
  • GC19M040334
  • GC19M040487
  • GC19M040274
  • GC19M040034

Summaries for ZNF780B Gene

GeneCards Summary for ZNF780B Gene

ZNF780B (Zinc Finger Protein 780B) is a Protein Coding gene. Diseases associated with ZNF780B include Fructose Intolerance, Hereditary. Among its related pathways are Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity. An important paralog of this gene is ZNF780A.

UniProtKB/Swiss-Prot Summary for ZNF780B Gene

Additional gene information for ZNF780B Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF780B Gene

Genomics for ZNF780B Gene

GeneHancer (GH) Regulatory Elements for ZNF780B Gene

Promoters and enhancers for ZNF780B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF780B on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF780B

Top Transcription factor binding sites by QIAGEN in the ZNF780B gene promoter:
  • GR
  • GR-alpha
  • Ik-2
  • IRF-7A
  • Pax-6
  • SREBP-1c
  • SRF
  • SRF (504 AA)
  • YY1
  • ZID

Genomic Locations for ZNF780B Gene

Genomic Locations for ZNF780B Gene
chr19:40,028,260-40,059,027
(GRCh38/hg38)
Size:
30,768 bases
Orientation:
Minus strand
chr19:40,534,167-40,562,116
(GRCh37/hg19)
Size:
27,950 bases
Orientation:
Minus strand

Genomic View for ZNF780B Gene

Genes around ZNF780B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF780B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF780B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF780B Gene

Proteins for ZNF780B Gene

  • Protein details for ZNF780B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y6R6-Z780B_HUMAN
    Recommended name:
    Zinc finger protein 780B
    Protein Accession:
    Q9Y6R6
    Secondary Accessions:
    • B9EH00

    Protein attributes for ZNF780B Gene

    Size:
    833 amino acids
    Molecular mass:
    96807 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF780B Gene

Post-translational modifications for ZNF780B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF780B Gene

Domains & Families for ZNF780B Gene

Gene Families for ZNF780B Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF780B Gene

Blocks:
  • C2H2-type zinc finger signature
  • KRAB box
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF780B Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 779 (Z780B_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9Y6R6

UniProtKB/Swiss-Prot:

Z780B_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF780B: view

Function for ZNF780B Gene

Molecular function for ZNF780B Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF780B Gene

Gene Ontology (GO) - Molecular Function for ZNF780B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IBA 21873635
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF780B: view
genes like me logo Genes that share phenotypes with ZNF780B: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF780B Gene

Localization for ZNF780B Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF780B Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF780B gene
Compartment Confidence
nucleus 4
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Centrosome (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF780B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IBA 21873635
genes like me logo Genes that share ontologies with ZNF780B: view

Pathways & Interactions for ZNF780B Gene

PathCards logo

SuperPathways for ZNF780B Gene

genes like me logo Genes that share pathways with ZNF780B: view

Pathways by source for ZNF780B Gene

1 KEGG pathway for ZNF780B Gene

Interacting Proteins for ZNF780B Gene

;

Gene Ontology (GO) - Biological Process for ZNF780B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF780B: view

No data available for SIGNOR curated interactions for ZNF780B Gene

Drugs & Compounds for ZNF780B Gene

No Compound Related Data Available

Transcripts for ZNF780B Gene

mRNA/cDNA for ZNF780B Gene

1 REFSEQ mRNAs :
4 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF780B Gene

No ASD Table

Relevant External Links for ZNF780B Gene

GeneLoc Exon Structure for
ZNF780B

Expression for ZNF780B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF780B Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF780B

SOURCE GeneReport for Unigene cluster for ZNF780B Gene:

Hs.101139
genes like me logo Genes that share expression patterns with ZNF780B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF780B Gene

Orthologs for ZNF780B Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF780B Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia LOC100684414 30
  • 78.22 (n)
ZNF780B 31
  • 53 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp780b 17 31 30
  • 70.58 (n)
1700049G17Rik 31
  • 53 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Zfp780b 30
  • 68.55 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 51 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia -- 31
  • 51 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 31
  • 45 (a)
ManyToMany
-- 31
  • 41 (a)
ManyToMany
-- 31
  • 33 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 43 (a)
OneToMany
Species where no ortholog for ZNF780B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF780B Gene

ENSEMBL:
Gene Tree for ZNF780B (if available)
TreeFam:
Gene Tree for ZNF780B (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF780B: view image

Paralogs for ZNF780B Gene

Paralogs for ZNF780B Gene

(516) SIMAP similar genes for ZNF780B Gene using alignment to 4 proteins:

  • Z780B_HUMAN
  • C9JTJ1_HUMAN
  • M0R0W9_HUMAN
  • M0R168_HUMAN