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The protein encoded by this gene is a member of the krueppel C2H2-type zinc-finger protein family, and it contains one KRAB domain and eighteen C2H2-type zinc fingers. This gene is a candidate gene for autism and variable cognitive impairment in the 16q24.3 microdeletion syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan ... See more...
Aliases for ZNF778 Gene
External Ids for ZNF778 Gene
- HGNC: 26479
- Entrez Gene: 197320
- Ensembl: ENSG00000170100
- UniProtKB: Q96MU6
Previous GeneCards Identifiers for ZNF778 Gene
- GC16P087812
- GC16P089284
- GC16P074983
Summaries for ZNF778 Gene
-
The protein encoded by this gene is a member of the krueppel C2H2-type zinc-finger protein family, and it contains one KRAB domain and eighteen C2H2-type zinc fingers. This gene is a candidate gene for autism and variable cognitive impairment in the 16q24.3 microdeletion syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2011]
GeneCards Summary for ZNF778 Gene
ZNF778 (Zinc Finger Protein 778) is a Protein Coding gene. Diseases associated with ZNF778 include 16Q24.3 Microdeletion Syndrome and Kbg Syndrome. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF560.
UniProtKB/Swiss-Prot Summary for ZNF778 Gene
-
May be involved in transcriptional regulation.
Additional gene information for ZNF778 Gene
- HGNC(26479)
- Entrez Gene(197320)
- Ensembl(ENSG00000170100)
- UniProtKB(Q96MU6)
- Open Targets Platform(ENSG00000170100)
- Search for ZNF778 at DataMed
- Search for ZNF778 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF778 Gene
Genomics for ZNF778 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ZNF778 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ZNF778 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF778
Genomic Locations for ZNF778 Gene
Genomic Locations for ZNF778 Gene
- chr16:89,202,112-89,237,141
- (GRCh38/hg38)
- Size:
- 35,030 bases
- Orientation:
- Plus strand
- chr16:89,284,111-89,295,965
- (GRCh37/hg19)
- Size:
- 11,855 bases
- Orientation:
- Plus strand
Genomic View for ZNF778 Gene
Genes around ZNF778 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16q24.3 by HGNC
- 16q24.3 by Entrez Gene
- 16q24.3 by Ensembl
ZNF778 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZNF778 Gene
Proteins for ZNF778 Gene
-
Protein details for ZNF778 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96MU6-ZN778_HUMAN
- Recommended name:
- Zinc finger protein 778
- Protein Accession:
- Q96MU6
- Q08AG0
Protein attributes for ZNF778 Gene
- Size:
- 729 amino acids
- Molecular mass:
- 81964 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAB71183.1; Type=Frameshift; Evidence={ECO:0000305};
Protein Expression for ZNF778 Gene
Post-translational modifications for ZNF778 Gene
Other Protein References for ZNF778 Gene
Antibody Products
- Novus Biologicals Antibodies for ZNF778
- Invitrogen Antibodies for ZNF778 (AFLGC-ZNF778)
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for ZNF778
- Origene Custom Protein Services for ZNF778
- Novus Biologicals proteins for ZNF778
No data available for DME Specific Peptides for ZNF778 Gene
Domains & Families for ZNF778 Gene
Gene Families for ZNF778 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ZNF778 Gene
- InterPro:
- Blocks:
-
- KRAB box
- ProtoNet:
Suggested Antigen Peptide Sequences for ZNF778 Gene
- GenScript: Design optimal peptide antigens:
-
- ZNF778 protein (A0PJ55_HUMAN)
- Zinc finger protein 778 (ZN778_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q96MU6- Family:
-
- Belongs to the krueppel C2H2-type zinc-finger protein family.
Function for ZNF778 Gene
Molecular function for ZNF778 Gene
- UniProtKB/Swiss-Prot Function:
- May be involved in transcriptional regulation.
Phenotypes From GWAS Catalog for ZNF778 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003700 | DNA-binding transcription factor activity | IBA | 21873635 |
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0043565 | sequence-specific DNA binding | IBA | 21873635 |
Phenotypes for ZNF778 Gene
- GenomeRNAi human phenotypes for ZNF778:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ZNF778 - Select products 50% OFF >
- * ZNF778 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ZNF778
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF778
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF778
miRNA for ZNF778 Gene
- miRTarBase miRNAs that target ZNF778
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF778
- Browse OriGene Inhibitory RNA Products For ZNF778
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF778
Clone Products
- Applied Biological Materials (abm): Clones for ZNF778 - Select products 50% OFF >
- * ZNF778 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ZNF778
- Addgene plasmids for ZNF778
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF778
Cell Line Products
-
Horizon Cell Lines for ZNF778
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF778 Gene
Localization for ZNF778 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZNF778 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytosol | 2 |
- Nuclear bodies (3)
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | 21873635 |
Pathways & Interactions for ZNF778 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Gene Expression |
.48
|
|
| 2 | Herpes simplex virus 1 infection | ||
Pathways by source for ZNF778 Gene
2 Reactome pathways for ZNF778 Gene
1 KEGG pathway for ZNF778 Gene
Interacting Proteins for ZNF778 Gene
Selected Interacting proteins:
Q96MU6-ZN778_HUMAN
ENSP00000405289
for ZNF778 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for ZNF778
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
No data available for SIGNOR curated interactions for ZNF778 Gene
Transcripts for ZNF778 Gene
mRNA/cDNA for ZNF778 Gene
- 3 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000306502 2386 nts (view in UCSC)
- ENST00000433976 3608 nts (view in UCSC)
- ENST00000564906 568 nts (view in UCSC)
- ENST00000565414 331 nts (view in UCSC)
- ENST00000565877 267 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ZNF778 - Select products 50% OFF >
- * ZNF778 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ZNF778
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF778
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF778
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF778
- Browse OriGene Inhibitory RNA Products For ZNF778
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF778
Clone Products
- Applied Biological Materials (abm): Clones for ZNF778 - Select products 50% OFF >
- * ZNF778 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ZNF778
- Addgene plasmids for ZNF778
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF778
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||
| SP2: | |||||||||||||||||
| SP3: | - |
Relevant External Links for ZNF778 Gene
- GeneLoc Exon Structure for
- ZNF778
Expression for ZNF778 Gene
This gene is overexpressed in Pancreas (48.7) and Platelet (18.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF778 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF778
SOURCE GeneReport for Unigene cluster for ZNF778 Gene:
Hs.647385Primer Products
-
OriGene qPCR primer pairs for ZNF778
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF778 Gene
Orthologs for ZNF778 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ZNF778 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Zfp26 30 17 |
|
||
| Zfp560 31 |
|
ManyToMany | |||
| Rat (Rattus norvegicus) |
Mammalia | Zfp26 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | -- 31 |
|
OneToMany |
- Species where no ortholog for ZNF778 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- Dog (Canis familiaris)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for ZNF778 Gene
- ENSEMBL:
- Gene Tree for ZNF778 (if available)
- TreeFam:
- Gene Tree for ZNF778 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ZNF778: view image
Paralogs for ZNF778 Gene
Paralogs for ZNF778 Gene
- ZNF560 5
- ZNF266 5
- ZNF559 5
- ZFP90 5
- ZNF555 5
- ZNF180 5
- ZNF599 5
- ZFP37 5
- ZNF177 5
- ZNF20 5
- ZNF264 5
- ZNF805 5
- ZNF596 5
- ZNF674 5
- ZNF25 5
- ZNF248 5
- ZNF529 5
- ZNF875 5
- ZNF846 5
- ZNF891 5
- ZNF10 5
- ZNF554 5
- ZNF582 5
- ZFP69B 5
- ZNF343 5
- ZNF404 5
- ZNF440 5
- ZNF619 5
- ZNF614 5
- ZNF337 5
- ZNF77 5
- ZNF749 5
- ZNF169 5
- ZNF133 5
- ZNF329 5
- ZNF425 5
- ZNF557 5
- ZNF566 5
- ZNF35 5
- ZNF559-ZNF177 5
- ZNF439 5
- ZNF19 5
- ZFP69 5
- PRDM9 5
- ZNF558 5
- ZNF684 5
- ZNF70 5
- ZNF491 5
- ZNF556 5
- ZNF550 5
- ZNF620 5
- ZNF669 5
- ZNF124 5
- ENSG00000267179 5
- ZNF763 5
- ZNF80 5
- ZNF705G 5
- ZNF705B 5
- ZNF705A 5
- ZNF705D 5
- ZNF705E 5
- ZNF589 5
- ZNF487 5
- ENSG00000256825 5
- KRBOX4 5
- ENSG00000261611 5
- ENSG00000256566 5
- ZNF69 5
(545) SIMAP similar genes for ZNF778 Gene using alignment to 4 proteins:
- ZN778_HUMAN
- A0PJ55_HUMAN
- H3BSD4_HUMAN
- H3BUU4_HUMAN
- ZNF625-ZNF20
- FIK
- ZNF738
- MGC12518
- ZNF669
- LOC101928664
- ZNF177
- ZFP90
- ZNF78L1
- ZNF121
- ZNF506
- KRBOX4
- ZNF84
- ZNF577
- ZNF846
- ZNF302
- ZNF675
- ZNF624
- ZNF721
- ZNF320
- ZNF625
- ZNF596
- ZNF586
- ZFS-4
- ZNF614
- ZNF331
- kr-znf3
- ZSCAN16
- ZNF763
- ZNF300P1
- ZNF283
- ZNF684
- ZNF226
- ZNF83
- ZNF415
- ZNF615
- ZNF235
- ZNF844
- ZNF528
- ZNF268
- ZNF519
- ZNF420
- ZNF350
- ZNF707
- ZNF573
- ZNF274
- ZNF225
- ZNF426
- ZNF208
- ZNF140
- ZNF81
- ZNF761
- ZNF345
- ZNF582
- ZNF781
- ZNF724P
- ZNF718
- ZNF682
- KRBOX1
- ZNF583
- ZNF75A
- ZNF79
- ZNF788
- ZNF391
- ZNF695
- ZNF397
- ZNF
- ZNF814
- ZNF627
- ZNF383
- ZNF789
- ZNF28
- ZNF224
- ZNF93
- ZNF780A
- ZNF55
- ZNF439
- ZNF43
- ZNF32
- ZNF230
- HZF16
- ZNF766
- ZNF248
- ZNF726
- ZNF181
- ZNF559
- ZNF709
- ZNF649
- ZNF90
- ZNF480
- ZNF461
- ZNF19
- ZNF850
- ZNF845
- ZNF595
- ZNF470
- ZNF195
- ZNF155
- ZNF141
- ZNF880
- ZNF829
- ZNF607
- ZNF56
- ZNF700
- ZNF677
- ZNF616
- ZNF571
- ZNF501
- ZNF436
- ZNF232
- ZNF146
- ZKSCAN7
- DKFZp666C237
- ZNF667
- ZNF790
- PRMD9
- ZNF793
- ZNF678
- ZNF175
- ZNF418
- ZSCAN21
- ZNF773
- ZNF558
- Nbla00121
- HZF30
- DKFZp686H10254
- ZNF432
- ZNF135
- ZSCAN31
- ZNF836
- ZNF10
- ZNF525
- zf30
- smap-7
- ZNF286B
- ZNF774
- ZNF71
- ZNF702P
- ZNF696
- ZNF323
- ZNF273
- ZNF266
- ZNF250
- ZNF204
- ZFP2
- POM121C
- HZF36
- DKFZp434J0650
- DKFZp313M0722
- ZFP30
- ZNF254
- PRDM9
- ZNF419
- ZNF613
- ZNF267
- ZNF471
- ZNF124
- ZNF286A
- ZNF780B
- ZNF20
- ZNF883
- ZNF852
- ZNF589
- ZNF500
- ZNF497
- ZNF167
- ZFP41
- DKFZp686N14223
- DKFZp666M039
- ZNF485
- ZNF813
- ZNF257
- ZNF222
- ZNF529
- ZNF540
- ZNF112
- ZNF101
- ZSCAN22
- ZNF833P
- ZNF853
- ZNF720
- ZNF679
- ZNF662
- ZNF660
- ZNF585B
- ZNF557
- ZNF544
- ZNF493
- ZNF260
- ZNF157
- ZNF12
- HZF41
- HZF40
- DKFZp434G1930
- ZNF233
- ZNF114
- ZNF791
- ZNF3
- ZNF776
- ZNF23
- ZNF570
- ZNF85
- ZNF491
- ZFP3
- DKFZp762K012
- DKFZp686L0787
- DKFZp686G16228
- DKFZp686D2168
- ZNF221
- ZNF599
- ZNF133
- ZIM3
- ZNF2
- ZSCAN30
- ZNF841
- ZSCAN5A
- ZNF735
- ZNF585A
- ZNF213
- ZNF688
- ZNF554
- ZNF527
- ZNF502
- ZNF433
- ZNF358
- ZNF33B
- ZNF282
- ZKSCAN8
- ZFS-1
- DKFZp686O1631
- DKFZp686M04222
- ZNF548
- ZNF630
- ZNF26
- ZNF35
- ZNF443
- ZNF626
- ZNF514
- ZNF317
- ZNF253
- ZNF227
- ZFP14
- ZNF676
- ZNF643
- ZFP69B
- ZNF699
- ZNF449
- WT1
- DKFZp686H20223
- DKFZp571N1833
- ZNF816
- ZNF300
- ZNF546
- ZNF347
- ZNF705A
- ZNF550
- ZNF66
- ZNF223
- ZSCAN29
- ZNF818P
- ZNF888
- ZNF835
- ZNF708
- ZNF665
- ZNF629
- ZNF623
- ZNF551
- ZNF492
- GZF1
- ZNF70
- ZNF670
- ZNF664
- ZNF569
- ZNF45
- ZNF329
- ZNF30
- ZNF16
- ZNF154
- ZNF138
- ZNF132
- ZKSCAN1
- ZFS-5
- ZFP1
- MST154
- KIAA1829
- DKFZp686K03205
- DKFZp547L155
- DKFZp434G1621
- A-328A3.4
- ZNF619
- ZNF562
- ZNF92
- ZNF737
- ZNF566
- ZNF34
- ZNF234
- ZSCAN2
- ZNF429
- ZNF772
- ZNF555
- ZNF25
- ZNF117
- ZFP92
- HZF17
- DKFZp686B16128
- ZNF17
- ZNF33A
- ZNF561
- ZNF782
- ZNF823
- ZNF76
- ZNF727
- ZNF410
- ZNF768
- ZNF534
- ZNF490
- ZNF285
- ZNF22
- ZNF184
- ZNF14
- ZNF137P
- ZIK1
- ZFP37
- HKR1
- ZNF169
- ZNF691
- ZNF486
- ZNF324B
- ZNF417
- ZNF98
- ZNF556
- ZNF430
- ZNF180
- ZSCAN23
- ZSCAN12
- ZNF716
- ZNF714
- ZNF771
- ZNF730
- ZNF697
- ZNF57
- ZNF567
- ZNF37A
- HZF11
- ZNF479
- ZNF354A
- MYNN
- ZNF808
- ZNF805
- ZNF600
- ZNF263
- ZNF134
- ZNF91
- ZNF75CP
- ZNF271
- ZNF73
- ZNF674
- ZNF498
- ZNF333
- ZNF264
- ZNF100
- ZFS-2
- ZNF578
- ZNF717
- ZNF7
- ZNF620
- ZNF568
- ZNF80
- ZNF681
- ZNF530
- ZNF460
- ZNF211
- DKFZp686O111
- ZNF549
- ZNF658
- ZNF563
- ZNF547
- ZNF354B
- ZNF431
- ZNF468
- ZNF879
- ZSCAN5D
- ZNF732
- ZNF355P
- ZNF143
- ZNF648
- ZNF605
- ZNF584
- ZNF572
- ZNF394
- ZNF337
- ZNF287
- ZNF256
- ZNF229
- ZFS-6
- ZFP28
- LOC126295
- GFI1B
- DKFZp686N0199
- DKFZp570I0164
- ZNF441
- ZNF77
- ZNF304
- ZNF728
- ZNF251
- ZNF680
- ZNF311
- ZNF285A
- ZNF284
- ZNF182
- HZF14
- GLI4
- ZNF160
- ZNF564
- ZNF655
- ZNF214
- ZNF565
- ZNF517
- ZNF275
- ZNF878
- ZNF806
- ZNF792
- ZNF764
- ZNF705F
- ZFP62
- PRDM1
- MAZ
- GD
- FEZF1
- ZNF72
- ZNF621
- ZNF560
- ZNF543
- ZNF416
- ZNF324
- ZNF189
- ZFP69
- PLAGL1
- ZNF799
- ZNF587
- ZNF442
- ZKSCAN4
- ZBTB17
- ZSCAN26
- ZNF860
- ZNF454
- ZNF726P1
- ZNF343
- ZNF136
- DKFZp686C13142
- ZNF701
- ZNF382
- ZNFN1A2
- ZSCAN20
- ZNF891
- ZNF705B
- ZNF652
- ZNF398
- ZKSCAN2
- ZBTB49
- E4F1
- ZNF74
- ZNF705D
- ZNF69
- ZNF671
- ZNF606
- ZNF483
- ZNF239
- GFI1
- CTCFL
- ZNF610
- ZNF552
- ZNF736
- ZNF765
- ZNF713
- ZKSCAN3
- ZNF510
- ZNF611
- ZNF705G
- ZNF705E
- ZNF587B
- ZNF44
- ZNF107
- ZFS-3
- DKFZp572F2170
- ZNF840
- ZNF404
- ZFP82
- ZF6
- ZNF876P
- ZNF594
- ZFP112
- ZNF658B
- ZNF354C
- ZNF322
- DKFZp547H249
- ZNF473
- ZNF786
- ZNF812
- ZNF668
- ZNF205
- ZBTB41
- RhitH
- FLJ00301
- ZSCAN32
- ZNF729
- TIPUH1
- BCL6B
- ZNF689
- ZNF41
- RBAK
- OSR2
- HZF28
- ZNF440
- ZNF672
- HKR3
- ZNF747
- ZNF384
- MECOM
- SNAI2
- ZSCAN10
- ZNF99
- ZNF837
- ZNF711
- PRDM16
- ZKSCAN5
- PRDM5
- PLZF
- ZBTB47
- ZNF8
- ZNF334
- ZFP64
- ZFX
- FIZ1
- ZNF197
- ZSCAN9
- GTF3A
- ZBTB40
- MZF1
- ZNF628
- ZBTB48
- ZNF749
- ZNF319
- OVOL3
- DKFZp686J1732
Variants for ZNF778 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF778 Gene
| SNP ID | Clinical significance and condition | Chr 16 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 708197 | Benign: not provided | 89,227,116(+) | C/T | NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT | |
| 708239 | Benign: not provided | 89,227,872(+) | C/T | NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT | |
| 712325 | Likely Benign: not provided | 89,222,140(+) | A/G | MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT | |
| rs150830617 | Benign: not specified | 89,224,749(+) | A/G | MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT,INTRON_VARIANT | |
| rs760873642 | Uncertain Significance: Microcephaly; Seizures; Global developmental delay; Obesity | 89,228,182(+) | C/T | MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv3066n100 | CNV | gain | 25217958 |
| esv1006131 | CNV | deletion | 20482838 |
| esv2665882 | CNV | deletion | 23128226 |
| esv2763149 | CNV | gain | 21179565 |
| esv3304105 | CNV | mobile element insertion | 20981092 |
| esv3441548 | CNV | insertion | 20981092 |
| esv3639571 | CNV | loss | 21293372 |
| esv3892939 | CNV | loss | 25118596 |
| nsv1063024 | CNV | gain | 25217958 |
| nsv428331 | CNV | gain+loss | 18775914 |
| nsv457622 | CNV | loss | 19166990 |
| nsv469681 | CNV | loss | 16826518 |
| nsv482951 | CNV | loss | 15286789 |
| nsv509638 | CNV | insertion | 20534489 |
| nsv573674 | CNV | gain | 21841781 |
| nsv573734 | CNV | loss | 21841781 |
| nsv827843 | CNV | gain | 20364138 |
| nsv827844 | CNV | gain | 20364138 |
Residual Variation Intolerance Score:
97.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.37;
63.44% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ZNF778 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF778 Gene
Disorders for ZNF778 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| 16q24.3 microdeletion syndrome |
|
|
| kbg syndrome |
|
|
| solitary median maxillary central incisor |
|
|
| autism |
|
|
| ureterocele |
|
|
Search ZNF778 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ZNF778
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF778 Gene
Publications for ZNF778 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
- VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3
- A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3
ExternalLinks
Products for ZNF778 Gene
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Sources for ZNF778 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
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- (44) Atlas
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- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
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- (90) CYP
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- (94) GeneReviews
- (95) GeneTex
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- (97) GTEx
- (98) ProteomicsDB
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- (100) DGIdb
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- (104) diseasecard
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