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Aliases for ZNF775 Gene

Aliases for ZNF775 Gene

  • Zinc Finger Protein 775 2 3 5

External Ids for ZNF775 Gene

Previous GeneCards Identifiers for ZNF775 Gene

  • GC07P149707
  • GC07P150067
  • GC07P143892
  • GC07P150086
  • GC07P150369

Summaries for ZNF775 Gene

GeneCards Summary for ZNF775 Gene

ZNF775 (Zinc Finger Protein 775) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is REPIN1.

UniProtKB/Swiss-Prot for ZNF775 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF775 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF775 Gene

Genomics for ZNF775 Gene

GeneHancer (GH) Regulatory Elements for ZNF775 Gene

Promoters and enhancers for ZNF775 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I150375 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 550.8 +1.8 1767 11.7 HDGF PKNOX1 FOXA2 SMAD1 ARID4B SIN3A DMAP1 IRF4 YY1 POLR2B ENSG00000284048 ZNF775 NUB1 REPIN1 ZNF777 ZNF767P ZNF862 ENSG00000244151 ZBED6CL TMEM176A
GH07I150398 Promoter/Enhancer 2 Ensembl ENCODE dbSUPER 21.4 +24.9 24864 11.2 MLX FEZF1 DMAP1 IRF4 YY1 E2F8 ZNF143 SP3 ZNF610 GLIS1 LOC728743 ZNF775 ENSG00000244151 NUB1 LRRC61 ZNF777 REPIN1 ZNF767P LOC105375564 ACTR3C
GH07I150319 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 11.9 -56.3 -56265 6.6 MLX DMAP1 IRF4 YY1 E2F8 SP3 MEF2D GLIS1 NBN NR2C1 LRRC61 GC07P150324 ACTR3C ENSG00000244151 ZNF775 LOC105375564 ZNF767P ZNF862 ZNF746 GC07P150294
GH07I149872 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 13.3 -505.8 -505834 2.3 HDGF PKNOX1 SMAD1 FOXA2 ARNT ZFP64 ARID4B SIN3A ZNF2 YY1 ATP6V0E2 ZNF783 ZNF767P ENSG00000271664 ZNF775 LOC155060 ZNF282 ZNF862 ZNF786 ZNF398
GH07I150434 Enhancer 1.3 FANTOM5 Ensembl ENCODE 20.2 +56.4 56424 1.8 HDGF RB1 BMI1 KLF5 IRF4 ZBTB40 ZNF766 ZNF207 ZNF143 ATF7 ZNF775 LOC105375564 RARRES2 LINC00996 ATP6V0E2 GIMAP8
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF775 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF775 gene promoter:

Genomic Locations for ZNF775 Gene

Genomic Locations for ZNF775 Gene
19,335 bases
Plus strand

Genomic View for ZNF775 Gene

Genes around ZNF775 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF775 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF775 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF775 Gene

Proteins for ZNF775 Gene

  • Protein details for ZNF775 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 775
    Protein Accession:
    Secondary Accessions:
    • Q8IY24

    Protein attributes for ZNF775 Gene

    537 amino acids
    Molecular mass:
    59752 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF775 Gene

Post-translational modifications for ZNF775 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF775 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF775 Gene

Domains & Families for ZNF775 Gene

Gene Families for ZNF775 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF775 Gene


Suggested Antigen Peptide Sequences for ZNF775 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF775: view

Function for ZNF775 Gene

Molecular function for ZNF775 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF775 Gene

Gene Ontology (GO) - Molecular Function for ZNF775 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF775: view
genes like me logo Genes that share phenotypes with ZNF775: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF775 Gene

Localization for ZNF775 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF775 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF775 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF775 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF775: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF775 Gene

Pathways & Interactions for ZNF775 Gene

SuperPathways for ZNF775 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF775: view

Pathways by source for ZNF775 Gene

2 Reactome pathways for ZNF775 Gene

Gene Ontology (GO) - Biological Process for ZNF775 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF775: view

No data available for SIGNOR curated interactions for ZNF775 Gene

Drugs & Compounds for ZNF775 Gene

No Compound Related Data Available

Transcripts for ZNF775 Gene

mRNA/cDNA for ZNF775 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(491) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF775 Gene

Zinc finger protein 775:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF775 Gene

No ASD Table

Relevant External Links for ZNF775 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF775 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF775 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF775 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF775 Gene:


SOURCE GeneReport for Unigene cluster for ZNF775 Gene:


Evidence on tissue expression from TISSUES for ZNF775 Gene

  • Nervous system(2.9)
genes like me logo Genes that share expression patterns with ZNF775: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF775 Gene

Orthologs for ZNF775 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF775 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF775 33 34
  • 99.57 (n)
(Canis familiaris)
Mammalia ZNF775 33 34
  • 86.4 (n)
(Bos Taurus)
Mammalia ZNF775 34
  • 80 (a)
(Mus musculus)
Mammalia Zfp775 33 16 34
  • 79.9 (n)
(Rattus norvegicus)
Mammalia Zfp775 33
  • 78.28 (n)
(Ornithorhynchus anatinus)
Mammalia ZNF775 34
  • 40 (a)
(Monodelphis domestica)
Mammalia ZNF775 34
  • 27 (a)
(Anolis carolinensis)
Reptilia ZNF775 34
  • 32 (a)
Species where no ortholog for ZNF775 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF775 Gene

Gene Tree for ZNF775 (if available)
Gene Tree for ZNF775 (if available)

Paralogs for ZNF775 Gene

Paralogs for ZNF775 Gene

genes like me logo Genes that share paralogs with ZNF775: view

Variants for ZNF775 Gene

Sequence variations from dbSNP and Humsavar for ZNF775 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000213400 -- 150,388,546(+) C/T intron_variant
rs1000265621 -- 150,388,268(+) A/G intron_variant
rs1000375585 -- 150,382,803(+) C/T intron_variant
rs1000786037 -- 150,386,171(+) G/A intron_variant
rs1000827637 -- 150,381,804(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF775 Gene

Variant ID Type Subtype PubMed ID
dgv11718n54 CNV loss 21841781
dgv3695n106 OTHER inversion 24896259
esv2392928 CNV deletion 18987734
esv2735383 CNV deletion 23290073
esv2735385 CNV deletion 23290073
esv3329578 CNV insertion 20981092
nsv1015582 CNV gain 25217958
nsv1034409 CNV gain 25217958
nsv1067934 OTHER inversion 25765185
nsv1151906 OTHER inversion 26484159
nsv477733 CNV novel sequence insertion 20440878
nsv521407 CNV loss 19592680
nsv608990 CNV gain 21841781
nsv951646 CNV deletion 24416366
nsv951647 CNV deletion 24416366

Variation tolerance for ZNF775 Gene

Residual Variation Intolerance Score: 41.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.42; 27.84% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF775 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF775 Gene

Disorders for ZNF775 Gene

Additional Disease Information for ZNF775

No disorders were found for ZNF775 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF775 Gene

Publications for ZNF775 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  5. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A … Wanker EE (Science signaling 2011) 3 58

Products for ZNF775 Gene

Sources for ZNF775 Gene

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