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Aliases for ZNF771 Gene

Aliases for ZNF771 Gene

  • Zinc Finger Protein 771 2 3 5
  • Mesenchymal Stem Cell Protein DSC43 3 4
  • DSC43 3

External Ids for ZNF771 Gene

Previous GeneCards Identifiers for ZNF771 Gene

  • GC16P030327
  • GC16P027980

Summaries for ZNF771 Gene

GeneCards Summary for ZNF771 Gene

ZNF771 (Zinc Finger Protein 771) is a Protein Coding gene. Among its related pathways are Gene Expression. An important paralog of this gene is ZNF7.

UniProtKB/Swiss-Prot for ZNF771 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF771 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF771 Gene

Genomics for ZNF771 Gene

GeneHancer (GH) Regulatory Elements for ZNF771 Gene

Promoters and enhancers for ZNF771 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16I030406 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 550.8 +0.4 368 1.9 HDGF CLOCK ARID4B SIN3A YBX1 DMAP1 ZNF2 SLC30A9 E2F8 ZNF143 ZNF771 ZNF785 FUS ENSG00000261367 GC16M030397
GH16I030956 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 13.1 +550.6 550594 3.4 CLOCK FEZF1 DMAP1 YY1 ZNF213 E2F8 ZNF143 ZNF548 ZNF263 SP3 SETD1A ENSG00000275263 FUS SRCAP INO80E ENSG00000260267 SMG1P5 ZNF764 BCL7C ENSG00000260304
GH16I029972 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE 13.1 -431.7 -431740 6.1 HDGF PKNOX1 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 TAOK2 SETD1A INO80E NPIPB12 SRCAP NPIPB13 ENSG00000260367 ZNF764 ZNF785 BCL7C
GH16I030182 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 13.1 -222.0 -222042 6.4 HDGF PKNOX1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 IRF4 E2F8 CORO1A ENSG00000261416 SMG1P5 SETD1A ZNF689 ZNF688 FBRS ZNF646 INO80E PRRT2
GH16I030785 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 13.1 +379.4 379441 3.4 MLX ZFP64 ARID4B SIN3A ZNF2 ZBTB7B YY1 SLC30A9 ZNF213 E2F8 ZNF629 SRCAP SETD1A ENSG00000260267 INO80E SMG1P5 ENSG00000260304 ZNF764 NPIPB13 RNF40
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF771 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF771 gene promoter:

Genomic Locations for ZNF771 Gene

Genomic Locations for ZNF771 Gene
chr16:30,407,297-30,431,108
(GRCh38/hg38)
Size:
23,812 bases
Orientation:
Plus strand
chr16:30,418,618-30,440,920
(GRCh37/hg19)

Genomic View for ZNF771 Gene

Genes around ZNF771 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF771 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF771 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF771 Gene

Proteins for ZNF771 Gene

  • Protein details for ZNF771 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7L3S4-ZN771_HUMAN
    Recommended name:
    Zinc finger protein 771
    Protein Accession:
    Q7L3S4
    Secondary Accessions:
    • Q8TAQ7
    • Q9NYI6

    Protein attributes for ZNF771 Gene

    Size:
    317 amino acids
    Molecular mass:
    35702 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAF65445.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF771 Gene

Post-translational modifications for ZNF771 Gene

No Post-translational modifications

Other Protein References for ZNF771 Gene

No data available for DME Specific Peptides for ZNF771 Gene

Domains & Families for ZNF771 Gene

Gene Families for ZNF771 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF771 Gene

Suggested Antigen Peptide Sequences for ZNF771 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7L3S4

UniProtKB/Swiss-Prot:

ZN771_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF771: view

Function for ZNF771 Gene

Molecular function for ZNF771 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF771 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF771: view
genes like me logo Genes that share phenotypes with ZNF771: view

Animal Model Products

CRISPR Products

miRNA for ZNF771 Gene

miRTarBase miRNAs that target ZNF771

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF771 Gene

Localization for ZNF771 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF771 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF771 gene
Compartment Confidence
nucleus 5

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoli (2)
  • Nucleus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF771 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005730 nucleolus IDA --
genes like me logo Genes that share ontologies with ZNF771: view

Pathways & Interactions for ZNF771 Gene

SuperPathways for ZNF771 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF771: view

Pathways by source for ZNF771 Gene

2 Reactome pathways for ZNF771 Gene

Gene Ontology (GO) - Biological Process for ZNF771 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF771: view

No data available for SIGNOR curated interactions for ZNF771 Gene

Drugs & Compounds for ZNF771 Gene

No Compound Related Data Available

Transcripts for ZNF771 Gene

Unigene Clusters for ZNF771 Gene

Zinc finger protein 771:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF771 Gene

No ASD Table

Relevant External Links for ZNF771 Gene

GeneLoc Exon Structure for
ZNF771
ECgene alternative splicing isoforms for
ZNF771

Expression for ZNF771 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF771 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF771 Gene

This gene is overexpressed in Adipocyte (31.5), Lung (27.0), and Ovary (10.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF771 Gene



Protein tissue co-expression partners for ZNF771 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF771 Gene:

ZNF771

SOURCE GeneReport for Unigene cluster for ZNF771 Gene:

Hs.148584

Evidence on tissue expression from TISSUES for ZNF771 Gene

  • Nervous system(4.4)
  • Muscle(4.3)
  • Liver(2.4)
genes like me logo Genes that share expression patterns with ZNF771: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF771 Gene

Orthologs for ZNF771 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF771 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF771 33 34
  • 99.47 (n)
dog
(Canis familiaris)
Mammalia ZNF771 33 34
  • 93.69 (n)
cow
(Bos Taurus)
Mammalia ZNF771 33 34
  • 91.83 (n)
mouse
(Mus musculus)
Mammalia Zfp771 33 16 34
  • 90.54 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF771 34
  • 88 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii zgc:173575 34
  • 42 (a)
ManyToMany
si:dkey-191j3.3 34
  • 38 (a)
ManyToMany
si:dkey-20i20.10 34
  • 34 (a)
ManyToMany
si:ch73-92e7.6 34
  • 31 (a)
ManyToMany
si:dkey-20i20.3 34
  • 31 (a)
ManyToMany
si:dkey-20i20.8 34
  • 27 (a)
ManyToMany
si:dkey-20i20.7 34
  • 26 (a)
ManyToMany
si:dkey-20i20.9 34
  • 25 (a)
ManyToMany
Species where no ortholog for ZNF771 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF771 Gene

ENSEMBL:
Gene Tree for ZNF771 (if available)
TreeFam:
Gene Tree for ZNF771 (if available)

Paralogs for ZNF771 Gene

(482) SIMAP similar genes for ZNF771 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF771: view

Variants for ZNF771 Gene

Sequence variations from dbSNP and Humsavar for ZNF771 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000034393 -- 30,407,553(+) C/G 5_prime_UTR_variant
rs1000084996 -- 30,418,786(+) C/T downstream_transcript_variant
rs1000466592 -- 30,407,739(+) C/T intron_variant
rs1000636564 -- 30,411,091(+) G/T intron_variant
rs1000810747 -- 30,417,062(+) C/CC intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF771 Gene

Variant ID Type Subtype PubMed ID
nsv827612 CNV gain 20364138

Variation tolerance for ZNF771 Gene

Gene Damage Index Score: 0.89; 18.50% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF771 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF771

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF771 Gene

Disorders for ZNF771 Gene

Additional Disease Information for ZNF771

No disorders were found for ZNF771 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF771 Gene

Publications for ZNF771 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58

Products for ZNF771 Gene

Sources for ZNF771 Gene

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