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Aliases for ZNF770 Gene

Aliases for ZNF770 Gene

  • Zinc Finger Protein 770 2 3 5
  • PRO1914 3

External Ids for ZNF770 Gene

Previous GeneCards Identifiers for ZNF770 Gene

  • GC15M033058
  • GC15M035270
  • GC15M012115

Summaries for ZNF770 Gene

GeneCards Summary for ZNF770 Gene

ZNF770 (Zinc Finger Protein 770) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA polymerase II transcription factor activity, sequence-specific DNA binding.

UniProtKB/Swiss-Prot for ZNF770 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF770 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF770 Gene

Genomics for ZNF770 Gene

GeneHancer (GH) Regulatory Elements for ZNF770 Gene

Promoters and enhancers for ZNF770 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I034984 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 558.8 +1.2 1210 5 PKNOX1 SMAD1 FOXA2 ZFP64 ARID4B SIN3A FEZF1 ZNF2 IRF4 YY1 ZNF770 AQR HNRNPLP2 NUTM1 ENSG00000279364
GH15I034968 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 7.7 +18.8 18828 1.9 HDGF FOXA2 PKNOX1 SMAD1 ARNT ZFP64 ARID4B SIN3A DMAP1 YY1 AQR GOLGA8A HNRNPLP2 GOLGA8B NUTM1 ENSG00000259665 ENSG00000259336 ZNF770 GC15P034944
GH15I034993 Enhancer 0.8 ENCODE 10.6 -6.4 -6369 2.2 BATF IRF4 ZBTB40 ZNF766 ETV6 BCLAF1 IKZF2 RUNX3 CAVIN1 ZBTB2 ENSG00000259181 AQR GOLGA8A ZNF770 LOC105370764 ENSG00000280396
GH15I035018 Enhancer 0.8 Ensembl ENCODE 8.8 -31.7 -31722 3.2 CTCF SP3 ZNF740 HLF CEBPB SIN3A NFXL1 SP1 VEZF1 POU5F1 ZNF770 AQR ENSG00000259587 ENSG00000259181 LOC105370763 ENSG00000259665
GH15I034854 Enhancer 0.6 ENCODE 4.9 +132.9 132852 1.6 ZSCAN21 JUND ZBTB48 ZNF692 STAT3 CEBPB FOS TCF7L2 ACTC1 GJD2 LOC101928174 ENSG00000259181 ZNF770 LOC100132824 RPL36AP8 AQR
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF770 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF770 gene promoter:

Genomic Locations for ZNF770 Gene

Genomic Locations for ZNF770 Gene
9,956 bases
Minus strand

Genomic View for ZNF770 Gene

Genes around ZNF770 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF770 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF770 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF770 Gene

Proteins for ZNF770 Gene

  • Protein details for ZNF770 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 770
    Protein Accession:
    Secondary Accessions:
    • Q6ZMZ6
    • Q9NWV2

    Protein attributes for ZNF770 Gene

    691 amino acids
    Molecular mass:
    80007 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAD18579.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF770 Gene

Post-translational modifications for ZNF770 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF770 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF770 Gene

Domains & Families for ZNF770 Gene

Gene Families for ZNF770 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF770 Gene

Suggested Antigen Peptide Sequences for ZNF770 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF770: view

Function for ZNF770 Gene

Molecular function for ZNF770 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF770 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF770: view
genes like me logo Genes that share phenotypes with ZNF770: view

miRNA for ZNF770 Gene

miRTarBase miRNAs that target ZNF770

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF770 Gene

Localization for ZNF770 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF770 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF770 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF770 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZNF770: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF770 Gene

Pathways & Interactions for ZNF770 Gene

SuperPathways for ZNF770 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF770: view

Pathways by source for ZNF770 Gene

2 Reactome pathways for ZNF770 Gene

Gene Ontology (GO) - Biological Process for ZNF770 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006357 regulation of transcription by RNA polymerase II IEA --
genes like me logo Genes that share ontologies with ZNF770: view

No data available for SIGNOR curated interactions for ZNF770 Gene

Drugs & Compounds for ZNF770 Gene

No Compound Related Data Available

Transcripts for ZNF770 Gene

mRNA/cDNA for ZNF770 Gene

Unigene Clusters for ZNF770 Gene

Zinc finger protein 770:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF770 Gene

No ASD Table

Relevant External Links for ZNF770 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF770 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF770 Gene

Protein differential expression in normal tissues from HIPED for ZNF770 Gene

This gene is overexpressed in Amniocyte (50.8) and Lung (11.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF770 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF770 Gene:


SOURCE GeneReport for Unigene cluster for ZNF770 Gene:

genes like me logo Genes that share expression patterns with ZNF770: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF770 Gene

Orthologs for ZNF770 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF770 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF770 33 34
  • 99.66 (n)
(Canis familiaris)
Mammalia ZNF770 33 34
  • 88.77 (n)
(Bos Taurus)
Mammalia ZNF770 33 34
  • 87.68 (n)
(Rattus norvegicus)
Mammalia Zfp770 33
  • 83.14 (n)
(Mus musculus)
Mammalia Zfp770 33 16 34
  • 82.58 (n)
(Monodelphis domestica)
Mammalia ZNF770 34
  • 64 (a)
(Gallus gallus)
Aves ZNF770 33 34
  • 65.81 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia znf770 33
  • 54.03 (n)
Str.12795 33
(Danio rerio)
Actinopterygii BX004873.1 34
  • 29 (a)
fruit fly
(Drosophila melanogaster)
Insecta crol 34
  • 14 (a)
Species where no ortholog for ZNF770 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF770 Gene

Gene Tree for ZNF770 (if available)
Gene Tree for ZNF770 (if available)

Paralogs for ZNF770 Gene Pseudogenes for ZNF770 Gene

genes like me logo Genes that share paralogs with ZNF770: view

No data available for Paralogs for ZNF770 Gene

Variants for ZNF770 Gene

Sequence variations from dbSNP and Humsavar for ZNF770 Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000546953 -- 34,989,947(-) C/T upstream_transcript_variant
rs1000783648 -- 34,982,785(-) T/C coding_sequence_variant, missense_variant
rs1001134146 -- 34,982,235(-) A/C coding_sequence_variant, missense_variant
rs1001618515 -- 34,987,278(-) C/A/T intron_variant
rs1001833659 -- 34,987,048(-) T/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF770 Gene

Variant ID Type Subtype PubMed ID
esv2761865 CNV gain 21179565
esv3569431 CNV gain 25503493
nsv522411 CNV gain 19592680
nsv827295 CNV gain 20364138

Variation tolerance for ZNF770 Gene

Residual Variation Intolerance Score: 9.69% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.45; 28.31% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF770 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF770 Gene

Disorders for ZNF770 Gene

Additional Disease Information for ZNF770

No disorders were found for ZNF770 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF770 Gene

Publications for ZNF770 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58

Products for ZNF770 Gene

Sources for ZNF770 Gene

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