Aliases for ZNF764 Gene

Aliases for ZNF764 Gene

  • Zinc Finger Protein 764 2 3 4 5

External Ids for ZNF764 Gene

Previous GeneCards Identifiers for ZNF764 Gene

  • GC16M030473
  • GC16M030565
  • GC16M028128

Summaries for ZNF764 Gene

GeneCards Summary for ZNF764 Gene

ZNF764 (Zinc Finger Protein 764) is a Protein Coding gene. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ENSG00000261459.

UniProtKB/Swiss-Prot Summary for ZNF764 Gene

Additional gene information for ZNF764 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF764 Gene

Genomics for ZNF764 Gene

GeneHancer (GH) Regulatory Elements for ZNF764 Gene

Promoters and enhancers for ZNF764 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF764 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF764 gene promoter:
  • E2F
  • E2F-1
  • E2F-2
  • E2F-3a
  • E2F-4
  • E2F-5
  • Pax-5
  • STAT1
  • STAT1alpha
  • STAT1beta

Genomic Locations for ZNF764 Gene

Genomic Locations for ZNF764 Gene
4,735 bases
Minus strand
4,735 bases
Minus strand

Genomic View for ZNF764 Gene

Genes around ZNF764 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF764 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF764 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF764 Gene

Proteins for ZNF764 Gene

  • Protein details for ZNF764 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 764
    Protein Accession:
    Secondary Accessions:
    • A8MZF4
    • B3KSN2
    • H9KV99
    • Q9BWS1

    Protein attributes for ZNF764 Gene

    408 amino acids
    Molecular mass:
    44943 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF764 Gene


neXtProt entry for ZNF764 Gene

Post-translational modifications for ZNF764 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF764 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF764 Gene

Domains & Families for ZNF764 Gene

Gene Families for ZNF764 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF764 Gene

Suggested Antigen Peptide Sequences for ZNF764 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 764 (ZN764_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF764: view

Function for ZNF764 Gene

Molecular function for ZNF764 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF764 Gene

Gene Ontology (GO) - Molecular Function for ZNF764 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific ISA --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 16189514
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF764: view
genes like me logo Genes that share phenotypes with ZNF764: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF764 Gene

Localization for ZNF764 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF764 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF764 gene
Compartment Confidence
nucleus 4
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF764 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF764: view

Pathways & Interactions for ZNF764 Gene

genes like me logo Genes that share pathways with ZNF764: view

Pathways by source for ZNF764 Gene

2 Reactome pathways for ZNF764 Gene
1 KEGG pathway for ZNF764 Gene

Gene Ontology (GO) - Biological Process for ZNF764 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006357 regulation of transcription by RNA polymerase II IEA --
genes like me logo Genes that share ontologies with ZNF764: view

No data available for SIGNOR curated interactions for ZNF764 Gene

Drugs & Compounds for ZNF764 Gene

No Compound Related Data Available

Transcripts for ZNF764 Gene

mRNA/cDNA for ZNF764 Gene

(2) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(79) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF764 Gene

No ASD Table

Relevant External Links for ZNF764 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF764 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF764 Gene

Protein differential expression in normal tissues from HIPED for ZNF764 Gene

This gene is overexpressed in Adipocyte (68.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF764 Gene

Protein tissue co-expression partners for ZNF764 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF764 Gene:


SOURCE GeneReport for Unigene cluster for ZNF764 Gene:


Evidence on tissue expression from TISSUES for ZNF764 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with ZNF764: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF764 Gene

Orthologs for ZNF764 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF764 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF764 33 32
  • 99.18 (n)
(Bos Taurus)
Mammalia ZNF764 32
  • 82.72 (n)
(Rattus norvegicus)
Mammalia LOC102553962 32
  • 70.15 (n)
(Mus musculus)
Mammalia Zfp764 17 32
  • 68.87 (n)
Zfp747 33
  • 38 (a)
(Monodelphis domestica)
Mammalia -- 33
  • 63 (a)
(Canis familiaris)
Mammalia -- 33
  • 34 (a)
Species where no ortholog for ZNF764 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF764 Gene

Gene Tree for ZNF764 (if available)
Gene Tree for ZNF764 (if available)
Evolutionary constrained regions (ECRs) for ZNF764: view image

Paralogs for ZNF764 Gene

(313) SIMAP similar genes for ZNF764 Gene using alignment to 1 proteins:

  • ZN764_HUMAN
genes like me logo Genes that share paralogs with ZNF764: view

Variants for ZNF764 Gene

Sequence variations from dbSNP and Humsavar for ZNF764 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000507027 -- 30,556,394(-) C/A intron_variant
rs1000960590 -- 30,557,147(-) A/T intron_variant
rs1001727539 -- 30,556,653(-) T/C intron_variant
rs1002504999 -- 30,554,273(-) G/A 3_prime_UTR_variant
rs1002800907 -- 30,557,526(-) AGAG/AG intron_variant

Variation tolerance for ZNF764 Gene

Residual Variation Intolerance Score: 84.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.73; 57.63% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF764 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF764 Gene

Disorders for ZNF764 Gene

Additional Disease Information for ZNF764

No disorders were found for ZNF764 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF764 Gene

Publications for ZNF764 Gene

  1. ZNF764 haploinsufficiency may explain partial glucocorticoid, androgen, and thyroid hormone resistance associated with 16p11.2 microdeletion. (PMID: 22577170) Kino T … Stratakis CA (The Journal of clinical endocrinology and metabolism 2012) 2 3 56
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 56
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 56
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 56
  5. A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. (PMID: 24104479) Vizeacoumar FJ … Moffat J (Molecular systems biology 2013) 3 56

Products for ZNF764 Gene

Sources for ZNF764 Gene