Aliases for ZNF763 Gene

Aliases for ZNF763 Gene

  • Zinc Finger Protein 763 2 3 4 5
  • Zinc Finger Protein 440 Like 3
  • DNA-Binding Protein 3
  • ZNF440L 3
  • ZNF 3

External Ids for ZNF763 Gene

Previous GeneCards Identifiers for ZNF763 Gene

  • GC19P011938
  • GC19P012099
  • GC19P012100
  • GC19P011650
  • GC19P012050

Summaries for ZNF763 Gene

GeneCards Summary for ZNF763 Gene

ZNF763 (Zinc Finger Protein 763) is a Protein Coding gene. Among its related pathways are Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and transcription coregulator activity. An important paralog of this gene is ENSG00000267179.

UniProtKB/Swiss-Prot Summary for ZNF763 Gene

Additional gene information for ZNF763 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF763 Gene

Genomics for ZNF763 Gene

GeneHancer (GH) Regulatory Elements for ZNF763 Gene

Promoters and enhancers for ZNF763 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J011963 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE CraniofacialAtlas 760.3 -0.1 -143 2.6 SP1 CTCF NR2F6 NFYC RAD21 NKRF POLR2A MLLT1 RELA IKZF1 ZNF763 ZNF433-AS1 ZNF788P VN2R21P ENSG00000267179
GH19J011977 Promoter 0.3 EPDnew 761.3 +12.0 12025 0.1 ZNF763 piR-40312 piR-57387-026 ENSG00000267179
GH19J012774 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 56.6 +820.8 820758 23 ZNF785 SIN3A ZNF24 SP1 ZBTB40 CTCF SREBF1 SIX5 ZBTB6 FOXA1 IER2 ENSG00000267212 MIR5684 HOOK2 CCDC130 ZNF136 ZNF44 ZNF791 ZNF564 WDR83OS
GH19J012918 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 52.3 +954.8 954833 2.2 PPP1R10 E2F8 ZNF785 SIN3A SP1 POLR2A HCFC1 RUNX1 ZNF362 MYC MIR5695 SYCE2 CCDC130 ZNF136 ZNF700 ZNF44 ZNF564 TRMT1 ZNF20 ZNF763
GH19J011534 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 38.3 -427.1 -427104 6.1 GTF3C2 ZNF785 ZBTB40 SP1 CTCF RBPJ SMARCE1 ATF1 CREB1 HCFC1 CNN1 MF281430-040 ILF3 KRI1 ZNF700 ZNF136 ZNF44 ZNF627 ZNF799 ZNF878
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF763 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZNF763 Gene

Genomic Locations for ZNF763 Gene
chr19:11,965,037-11,980,399
(GRCh38/hg38)
Size:
15,363 bases
Orientation:
Plus strand
chr19:12,035,890-12,091,214
(GRCh37/hg19)
Size:
55,325 bases
Orientation:
Plus strand

Genomic View for ZNF763 Gene

Genes around ZNF763 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF763 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF763 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF763 Gene

Proteins for ZNF763 Gene

  • Protein details for ZNF763 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q0D2J5-ZN763_HUMAN
    Recommended name:
    Zinc finger protein 763
    Protein Accession:
    Q0D2J5
    Secondary Accessions:
    • B3KRU3
    • B4DRE7

    Protein attributes for ZNF763 Gene

    Size:
    394 amino acids
    Molecular mass:
    46099 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF763 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF763 Gene

Post-translational modifications for ZNF763 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF763 Gene

Domains & Families for ZNF763 Gene

Gene Families for ZNF763 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF763 Gene

Suggested Antigen Peptide Sequences for ZNF763 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ58613, highly similar to Homo sapiens zinc finger protein 440 like (ZNF440L), mRNA (B4DRE7_HUMAN)
  • Zinc finger protein 763 (ZN763_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q0D2J5

UniProtKB/Swiss-Prot:

ZN763_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF763: view

Function for ZNF763 Gene

Molecular function for ZNF763 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF763 Gene

Gene Ontology (GO) - Molecular Function for ZNF763 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific ISA --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF763: view
genes like me logo Genes that share phenotypes with ZNF763: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF763 Gene

Localization for ZNF763 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF763 Gene

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF763 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF763: view

No data available for Subcellular locations from COMPARTMENTS for ZNF763 Gene

Pathways & Interactions for ZNF763 Gene

PathCards logo

SuperPathways for ZNF763 Gene

genes like me logo Genes that share pathways with ZNF763: view

Pathways by source for ZNF763 Gene

1 KEGG pathway for ZNF763 Gene

Interacting Proteins for ZNF763 Gene

Gene Ontology (GO) - Biological Process for ZNF763 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006357 regulation of transcription by RNA polymerase II IEA --
genes like me logo Genes that share ontologies with ZNF763: view

No data available for SIGNOR curated interactions for ZNF763 Gene

Drugs & Compounds for ZNF763 Gene

No Compound Related Data Available

Transcripts for ZNF763 Gene

mRNA/cDNA for ZNF763 Gene

(4) REFSEQ mRNAs :
(8) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF763 Gene

No ASD Table

Relevant External Links for ZNF763 Gene

GeneLoc Exon Structure for
ZNF763
ECgene alternative splicing isoforms for
ZNF763

Expression for ZNF763 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF763 Gene

Protein differential expression in normal tissues from HIPED for ZNF763 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF763 Gene



Protein tissue co-expression partners for ZNF763 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF763 Gene:

ZNF763

SOURCE GeneReport for Unigene cluster for ZNF763 Gene:

Hs.646386
genes like me logo Genes that share expression patterns with ZNF763: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF763 Gene

Orthologs for ZNF763 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF763 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 33
  • 98 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 33
  • 39 (a)
ManyToMany
Species where no ortholog for ZNF763 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF763 Gene

ENSEMBL:
Gene Tree for ZNF763 (if available)
TreeFam:
Gene Tree for ZNF763 (if available)

Paralogs for ZNF763 Gene

(517) SIMAP similar genes for ZNF763 Gene using alignment to 8 proteins:

  • ZN763_HUMAN
  • B4DRE7_HUMAN
  • F5H0A9_HUMAN
  • K7EJ80_HUMAN
  • K7EJF3_HUMAN
  • K7EJH5_HUMAN
  • K7EPL6_HUMAN
  • K7ESF6_HUMAN
genes like me logo Genes that share paralogs with ZNF763: view

Variants for ZNF763 Gene

Sequence variations from dbSNP and Humsavar for ZNF763 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000031080 -- 11,974,612(+) C/G/T intron_variant
rs1000307814 -- 11,963,343(+) C/G/T upstream_transcript_variant
rs1000711128 -- 11,963,143(+) GCAG/GCAGCAG upstream_transcript_variant
rs1000948702 -- 11,972,766(+) T/C intron_variant
rs1001060725 -- 11,967,010(+) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF763 Gene

Variant ID Type Subtype PubMed ID
esv2718189 CNV deletion 23290073
esv3643688 CNV loss 21293372
nsv525966 CNV gain 19592680
nsv578619 CNV loss 21841781
nsv960791 CNV duplication 23825009

Variation tolerance for ZNF763 Gene

Residual Variation Intolerance Score: 95.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.87; 48.39% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF763 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF763

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF763 Gene

Disorders for ZNF763 Gene

Additional Disease Information for ZNF763

No disorders were found for ZNF763 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF763 Gene

Publications for ZNF763 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 56
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 56
  3. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M … Moll S (Journal of proteomics 2013) 3 56
  4. A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells. (PMID: 23284306) Xie L … Green MR (PLoS genetics 2012) 3 56
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 56

Products for ZNF763 Gene

Sources for ZNF763 Gene