Aliases for ZNF747 Gene

Aliases for ZNF747 Gene

  • Zinc Finger Protein 747 2 3 5
  • KRAB Domain-Containing Protein ZNF747 3 4
  • MGC2474 2
  • ZNF747 5

External Ids for ZNF747 Gene

Previous GeneCards Identifiers for ZNF747 Gene

  • GC16M030452
  • GC16M030453
  • GC16M030541
  • GC16M028106

Summaries for ZNF747 Gene

GeneCards Summary for ZNF747 Gene

ZNF747 (Zinc Finger Protein 747) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ENSG00000261459.

Additional gene information for ZNF747 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF747 Gene

Genomics for ZNF747 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZNF747 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF747 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF747

Top Transcription factor binding sites by QIAGEN in the ZNF747 gene promoter:
  • ATF
  • c-Ets-1
  • GATA-1
  • HNF-1
  • HNF-1A
  • NF-1
  • Nkx2-5
  • p53
  • PPAR-gamma2

Genomic Locations for ZNF747 Gene

Genomic Locations for ZNF747 Gene
4,981 bases
Minus strand
9,425 bases
Minus strand

Genomic View for ZNF747 Gene

Genes around ZNF747 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF747 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF747 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF747 Gene

Proteins for ZNF747 Gene

  • Protein details for ZNF747 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    KRAB domain-containing protein ZNF747
    Protein Accession:
    Secondary Accessions:
    • A8K827
    • B7WNU3
    • Q59FB4
    • Q96NW0

    Protein attributes for ZNF747 Gene

    191 amino acids
    Molecular mass:
    20610 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB70760.1; Type=Erroneous termination; Note=Truncated C-terminus.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF747 Gene


neXtProt entry for ZNF747 Gene

Post-translational modifications for ZNF747 Gene

No Post-translational modifications

Other Protein References for ZNF747 Gene

No data available for DME Specific Peptides for ZNF747 Gene

Domains & Families for ZNF747 Gene

Gene Families for ZNF747 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF747 Gene

  • KRAB box

Suggested Antigen Peptide Sequences for ZNF747 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ54920, moderately similar to Homo sapiens zinc finger protein 689 (ZNF689), mRNA (B7Z5R0_HUMAN)
  • KRAB domain-containing protein ZNF747 (ZN747_HUMAN)
genes like me logo Genes that share domains with ZNF747: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ZNF747 Gene

Function for ZNF747 Gene

Phenotypes From GWAS Catalog for ZNF747 Gene

Gene Ontology (GO) - Molecular Function for ZNF747 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF747: view
genes like me logo Genes that share phenotypes with ZNF747: view

Animal Model Products

CRISPR Products

miRNA for ZNF747 Gene

miRTarBase miRNAs that target ZNF747

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF747

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF747 Gene

Localization for ZNF747 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF747 gene
Compartment Confidence
extracellular 1
nucleus 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Centrosome (2)
  • Cytosol (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZNF747 Gene

Pathways & Interactions for ZNF747 Gene

PathCards logo

SuperPathways for ZNF747 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF747: view

Pathways by source for ZNF747 Gene

2 Reactome pathways for ZNF747 Gene

Gene Ontology (GO) - Biological Process for ZNF747 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF747: view

No data available for SIGNOR curated interactions for ZNF747 Gene

Drugs & Compounds for ZNF747 Gene

No Compound Related Data Available

Transcripts for ZNF747 Gene

mRNA/cDNA for ZNF747 Gene

12 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF747

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF747 Gene

No ASD Table

Relevant External Links for ZNF747 Gene

GeneLoc Exon Structure for

Expression for ZNF747 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF747 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF747 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF747 Gene

Protein tissue co-expression partners for ZNF747 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF747

SOURCE GeneReport for Unigene cluster for ZNF747 Gene:


Evidence on tissue expression from TISSUES for ZNF747 Gene

  • Nervous system(4.5)
  • Skin(4.1)
genes like me logo Genes that share expression patterns with ZNF747: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF747 Gene

Orthologs for ZNF747 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF747 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia ZNF747 30
  • 79.89 (n)
(Monodelphis domestica)
Mammalia -- 31
  • 14 (a)
(Mus musculus)
Mammalia Zfp764 31
  • 13 (a)
E430018J23Rik 31
  • 13 (a)
Zfp747 31
  • 12 (a)
9130019O22Rik 31
  • 10 (a)
Species where no ortholog for ZNF747 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for ZNF747 Gene

Gene Tree for ZNF747 (if available)
Gene Tree for ZNF747 (if available)

Paralogs for ZNF747 Gene

genes like me logo Genes that share paralogs with ZNF747: view

Variants for ZNF747 Gene

Additional dbSNP identifiers (rs#s) for ZNF747 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF747 Gene

Variant ID Type Subtype PubMed ID
nsv1784 CNV insertion 18451855

Variation tolerance for ZNF747 Gene

Residual Variation Intolerance Score: 91.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.57; 44.61% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF747 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF747 Gene

Disorders for ZNF747 Gene

No disorders were found for ZNF747 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF747 Gene

Publications for ZNF747 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  2. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PMID: 10493829) Loftus BJ … Adams MD (Genomics 1999) 2 3
  3. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  4. Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations. (PMID: 31515488) Fragoza R … Yu H (Nature communications 2019) 3
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3

Products for ZNF747 Gene

Sources for ZNF747 Gene