Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF747 Gene

Aliases for ZNF747 Gene

  • Zinc Finger Protein 747 2 3 5

External Ids for ZNF747 Gene

Previous GeneCards Identifiers for ZNF747 Gene

  • GC16M030452
  • GC16M030453
  • GC16M030541
  • GC16M028106

Summaries for ZNF747 Gene

GeneCards Summary for ZNF747 Gene

ZNF747 (Zinc Finger Protein 747) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ENSG00000261459.

Additional gene information for ZNF747 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF747 Gene

Genomics for ZNF747 Gene

GeneHancer (GH) Regulatory Elements for ZNF747 Gene

Promoters and enhancers for ZNF747 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16I030533 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 561.2 +0.4 404 3.7 HDGF PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ENSG00000235560 ZNF747 ENSG00000261459 FUS SRCAP SMG1P5 SMG1P2 ZNF785 ENSG00000260267 PRR14
GH16I030566 Promoter/Enhancer 2.3 FANTOM5 Ensembl ENCODE dbSUPER 132.9 -34.5 -34527 6 ZFP64 FEZF1 DMAP1 YY1 ZNF213 E2F8 ZNF416 ZNF143 ZNF548 SP3 SETD1A SRCAP ENSG00000260267 FUS INO80E ZNF747 NPIPB13 ZNF764 SMG1P5 SMG1P2
GH16I030052 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 112.2 +481.1 481142 3.1 CLOCK MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 ALDOA FAM57B SETD1A SRCAP NPIPB12 INO80E SMG1P5 SMG1P2 ZNF764 ZNF747
GH16I030367 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 42.4 +159.3 159315 17 CLOCK FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 MYLPF ZNF48 TBC1D10B SEPT1 SETD1A SRCAP INO80E NPIPB12 SMG1P5 ZNF764
GH16I029972 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE 45.3 +559.8 559790 6.1 HDGF PKNOX1 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 TAOK2 SETD1A INO80E NPIPB12 SRCAP NPIPB13 ENSG00000260367 ZNF764 ZNF785 BCL7C
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF747 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF747 gene promoter:

Genomic Locations for ZNF747 Gene

Genomic Locations for ZNF747 Gene
chr16:30,530,367-30,535,347
(GRCh38/hg38)
Size:
4,981 bases
Orientation:
Minus strand
chr16:30,537,244-30,546,668
(GRCh37/hg19)

Genomic View for ZNF747 Gene

Genes around ZNF747 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF747 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF747 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF747 Gene

Proteins for ZNF747 Gene

  • Protein details for ZNF747 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BV97-ZN747_HUMAN
    Recommended name:
    KRAB domain-containing protein ZNF747
    Protein Accession:
    Q9BV97
    Secondary Accessions:
    • A8K827
    • B7WNU3
    • Q59FB4
    • Q96NW0

    Protein attributes for ZNF747 Gene

    Size:
    191 amino acids
    Molecular mass:
    20610 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB70760.1; Type=Erroneous termination; Positions=172; Note=Translated as Lys.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF747 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF747 Gene

Post-translational modifications for ZNF747 Gene

No Post-translational modifications

Other Protein References for ZNF747 Gene

No data available for DME Specific Peptides for ZNF747 Gene

Domains & Families for ZNF747 Gene

Gene Families for ZNF747 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF747 Gene

InterPro:
Blocks:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZNF747: view

No data available for UniProtKB/Swiss-Prot for ZNF747 Gene

Function for ZNF747 Gene

Phenotypes From GWAS Catalog for ZNF747 Gene

Gene Ontology (GO) - Molecular Function for ZNF747 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF747: view
genes like me logo Genes that share phenotypes with ZNF747: view

Animal Model Products

CRISPR Products

miRNA for ZNF747 Gene

miRTarBase miRNAs that target ZNF747

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF747 Gene

Localization for ZNF747 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF747 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Centrosome (2)
  • Cytosol (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF747 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with ZNF747: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ZNF747 Gene

Pathways & Interactions for ZNF747 Gene

SuperPathways for ZNF747 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF747: view

Pathways by source for ZNF747 Gene

2 Reactome pathways for ZNF747 Gene

Gene Ontology (GO) - Biological Process for ZNF747 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF747: view

No data available for SIGNOR curated interactions for ZNF747 Gene

Drugs & Compounds for ZNF747 Gene

No Compound Related Data Available

Transcripts for ZNF747 Gene

Unigene Clusters for ZNF747 Gene

Zinc finger protein 747:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF747 Gene

No ASD Table

Relevant External Links for ZNF747 Gene

GeneLoc Exon Structure for
ZNF747
ECgene alternative splicing isoforms for
ZNF747

Expression for ZNF747 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF747 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF747 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF747 Gene



Protein tissue co-expression partners for ZNF747 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF747 Gene:

ZNF747

SOURCE GeneReport for Unigene cluster for ZNF747 Gene:

Hs.592032

Evidence on tissue expression from TISSUES for ZNF747 Gene

  • Nervous system(4.5)
  • Skin(4.1)
genes like me logo Genes that share expression patterns with ZNF747: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF747 Gene

Orthologs for ZNF747 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF747 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia ZNF747 33
  • 79.89 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 14 (a)
OneToMany
mouse
(Mus musculus)
Mammalia E430018J23Rik 34
  • 13 (a)
ManyToMany
Zfp764 34
  • 13 (a)
ManyToMany
Zfp747 34
  • 12 (a)
ManyToMany
9130019O22Rik 34
  • 10 (a)
ManyToMany
Species where no ortholog for ZNF747 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF747 Gene

ENSEMBL:
Gene Tree for ZNF747 (if available)
TreeFam:
Gene Tree for ZNF747 (if available)

Paralogs for ZNF747 Gene

genes like me logo Genes that share paralogs with ZNF747: view

Variants for ZNF747 Gene

Sequence variations from dbSNP and Humsavar for ZNF747 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000853654 -- 30,535,879(-) C/T upstream_transcript_variant
rs1000868120 -- 30,530,020(-) G/A downstream_transcript_variant
rs1000978717 -- 30,530,482(-) G/A 3_prime_UTR_variant
rs1001373111 -- 30,536,258(-) T/C upstream_transcript_variant
rs1002021295 -- 30,536,344(-) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF747 Gene

Variant ID Type Subtype PubMed ID
nsv1784 CNV insertion 18451855

Variation tolerance for ZNF747 Gene

Residual Variation Intolerance Score: 91.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.57; 44.61% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF747 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF747

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF747 Gene

Disorders for ZNF747 Gene

Additional Disease Information for ZNF747

No disorders were found for ZNF747 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF747 Gene

Publications for ZNF747 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PMID: 10493829) Loftus BJ … Adams MD (Genomics 1999) 2 3 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  5. PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion. (PMID: 26598620) Dart AE … Wells CM (The Journal of cell biology 2015) 3 58

Products for ZNF747 Gene

Sources for ZNF747 Gene

Content
Loading form....