Aliases for ZNF737 Gene

Aliases for ZNF737 Gene

  • Zinc Finger Protein 737 2 3 4 5
  • ZNF102 2 3 4
  • Zinc Finger Protein 102 (Y3) 3
  • Zinc Finger Protein 102 4
  • ZNF737 5

External Ids for ZNF737 Gene

Previous GeneCards Identifiers for ZNF737 Gene

  • GC19U900745
  • GC19M020524
  • GC19M020720
  • GC19M020211
  • GC19M020804
  • GC19M020957
  • GC19M020614
  • GC19M021059
  • GC19M022569
  • GC19M022778
  • GC19M022831
  • GC19M023699
  • GC19M021115
  • GC19M021342
  • GC19M021518
  • GC19M021706
  • GC19M021901
  • GC19M022093
  • GC19M022282
  • GC19M022449

Summaries for ZNF737 Gene

GeneCards Summary for ZNF737 Gene

ZNF737 (Zinc Finger Protein 737) is a Protein Coding gene. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF66.

UniProtKB/Swiss-Prot Summary for ZNF737 Gene

Additional gene information for ZNF737 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF737 Gene

Genomics for ZNF737 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZNF737 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J020564 Promoter/Enhancer 1.5 Ensembl ENCODE CraniofacialAtlas 608.4 +0.4 407 2.4 SP1 CTCF POLR2A BACH1 FOS LARP7 PKNOX1 SMAD5 IKZF2 PBX2 ZNF737 ZNF626 piR-40586 LOC105372316 ENSG00000269110 ENSG00000269043 ZNF486
GH19J020432 Enhancer 0.5 FANTOM5 Ensembl 10.4 +133.6 133620 2 NFIB ENSG00000269043 LOC105372317 ZNF737 BNIP3P22 ZNF486
GH19J020466 Enhancer 0.3 Ensembl ENCODE 5.8 +99.0 99024 0.8 piR-53431-343 LINC00663 ZNF737 ZNF626 LOC105372316 ENSG00000269043 ZNF486
GH19J020367 Enhancer 0.9 FANTOM5 Ensembl ENCODE 1.3 +197.8 197792 1.2 CTCF RFX1 POLR2A RAD21 SIN3A SMARCA4 BACH1 MAFK LINC00663 ZNF682 ZNF737 piR-43651-004 BNIP3P21 ZNF826P lnc-ZNF737-3 ZNF486
GH19J020660 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE CraniofacialAtlas 0.2 -95.4 -95379 3.6 SP1 REST FOS DDX20 PKNOX1 POLR2A HDAC1 GABPA PBX2 MGA ZNF626 ENSG00000269110 LOC105372319 lnc-ZNF66-3 ENSG00000269779 RPL7AP10 ZNF431 piR-52475-008 ZNF737
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF737 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF737

Genomic Locations for ZNF737 Gene

Genomic Locations for ZNF737 Gene
34,592 bases
Minus strand
29,996 bases
Minus strand

Genomic View for ZNF737 Gene

Genes around ZNF737 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF737 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF737 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF737 Gene

Proteins for ZNF737 Gene

  • Protein details for ZNF737 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 737
    Protein Accession:
    Secondary Accessions:
    • C9JHM3

    Protein attributes for ZNF737 Gene

    536 amino acids
    Molecular mass:
    61931 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF737 Gene

Post-translational modifications for ZNF737 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF737 Gene

Domains & Families for ZNF737 Gene

Gene Families for ZNF737 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF737 Gene

Suggested Antigen Peptide Sequences for ZNF737 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 102 (ZN737_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF737: view

Function for ZNF737 Gene

Molecular function for ZNF737 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF737 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IBA 21873635
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF737: view
genes like me logo Genes that share phenotypes with ZNF737: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF737

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF737 Gene

Localization for ZNF737 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF737 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF737 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF737 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IBA 21873635
genes like me logo Genes that share ontologies with ZNF737: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF737 Gene

Pathways & Interactions for ZNF737 Gene

genes like me logo Genes that share pathways with ZNF737: view

Pathways by source for ZNF737 Gene

2 Reactome pathways for ZNF737 Gene
1 KEGG pathway for ZNF737 Gene

Interacting Proteins for ZNF737 Gene

Gene Ontology (GO) - Biological Process for ZNF737 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA,IBA 21873635
genes like me logo Genes that share ontologies with ZNF737: view

No data available for SIGNOR curated interactions for ZNF737 Gene

Drugs & Compounds for ZNF737 Gene

No Compound Related Data Available

Transcripts for ZNF737 Gene

mRNA/cDNA for ZNF737 Gene

2 NCBI additional mRNA sequence :
5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF737

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF737 Gene

No ASD Table

Relevant External Links for ZNF737 Gene

GeneLoc Exon Structure for

Expression for ZNF737 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF737 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF737

SOURCE GeneReport for Unigene cluster for ZNF737 Gene:

genes like me logo Genes that share expression patterns with ZNF737: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF737 Gene

Orthologs for ZNF737 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF737 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF737 30 31
  • 99.69 (n)
(Bos Taurus)
Mammalia -- 31
  • 56 (a)
(Monodelphis domestica)
Mammalia -- 31
  • 51 (a)
-- 31
  • 40 (a)
(Canis familiaris)
Mammalia -- 31
  • 40 (a)
(Mus musculus)
Mammalia Zfp386 31
  • 37 (a)
(Anolis carolinensis)
Reptilia -- 31
  • 54 (a)
-- 31
  • 42 (a)
-- 31
  • 40 (a)
-- 31
  • 35 (a)
-- 31
  • 32 (a)
-- 31
  • 32 (a)
-- 31
  • 32 (a)
-- 31
  • 30 (a)
Species where no ortholog for ZNF737 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for ZNF737 Gene

Gene Tree for ZNF737 (if available)
Gene Tree for ZNF737 (if available)
Evolutionary constrained regions (ECRs) for ZNF737: view image

Paralogs for ZNF737 Gene

(622) SIMAP similar genes for ZNF737 Gene using alignment to 5 proteins:

  • ZN737_HUMAN
  • M0R1D1_HUMAN
  • M0R1M3_HUMAN
  • M0R1M8_HUMAN
genes like me logo Genes that share paralogs with ZNF737: view

Variants for ZNF737 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF737 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs10410201 - p.Arg492Cys
rs10411329 - p.Lys516Glu
rs7254995 - p.Cys78Ser
rs9653154 - p.Val125Leu

Additional dbSNP identifiers (rs#s) for ZNF737 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF737 Gene

Variant ID Type Subtype PubMed ID
dgv1027e212 CNV loss 25503493
dgv17n14 CNV loss 18776910
dgv33e213 CNV loss 24956385
dgv3457n100 CNV gain 25217958
dgv3460n100 CNV loss 25217958
dgv3461n100 CNV loss 25217958
dgv3464n100 CNV loss 25217958
dgv3465n100 CNV loss 25217958
dgv399n27 CNV loss 19166990
dgv401n27 CNV loss 19166990
dgv402n27 CNV loss 19166990
dgv403n27 CNV loss 19166990
dgv509e201 CNV deletion 23290073
dgv6303n54 CNV loss 21841781
dgv6304n54 CNV loss 21841781
dgv6305n54 CNV gain 21841781
dgv6307n54 CNV loss 21841781
dgv630e199 CNV deletion 23128226
dgv6310n54 CNV loss 21841781
dgv6314n54 CNV loss 21841781
dgv69e203 CNV loss 21179565
esv1696645 CNV insertion 17803354
esv2422114 CNV deletion 20811451
esv2658579 CNV deletion 23128226
esv2718311 CNV deletion 23290073
esv2718314 CNV deletion 23290073
esv2718315 CNV deletion 23290073
esv2751781 CNV gain 17911159
esv2758749 CNV loss 17122850
esv3643886 CNV loss 21293372
esv3643888 CNV loss 21293372
esv3643889 CNV loss 21293372
esv3893172 CNV gain+loss 25118596
esv3893176 CNV gain 25118596
nsv1061245 CNV loss 25217958
nsv1125670 CNV tandem duplication 24896259
nsv1141886 OTHER inversion 24896259
nsv1160595 CNV deletion 26073780
nsv2437 CNV deletion 18451855
nsv442762 CNV loss 18776908
nsv458377 CNV gain 19166990
nsv458509 CNV loss 19166990
nsv514893 CNV loss 21397061
nsv517263 CNV gain+loss 19592680
nsv523471 CNV loss 19592680
nsv523499 CNV gain 19592680
nsv578809 CNV gain 21841781
nsv578810 CNV loss 21841781
nsv578909 CNV loss 21841781
nsv578910 CNV gain 21841781
nsv578911 CNV loss 21841781
nsv578912 CNV gain 21841781
nsv578913 CNV loss 21841781
nsv578914 CNV loss 21841781
nsv960807 CNV duplication 23825009

Variation tolerance for ZNF737 Gene

Residual Variation Intolerance Score: 98.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.19; 84.83% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF737 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF737 Gene

Disorders for ZNF737 Gene

No disorders were found for ZNF737 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF737 Gene

Publications for ZNF737 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  2. Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. (PMID: 8467795) Bellefroid EJ … Szpirer C (The EMBO journal 1993) 3 4
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4

Products for ZNF737 Gene

Sources for ZNF737 Gene