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Aliases for ZNF736 Gene

Aliases for ZNF736 Gene

  • Zinc Finger Protein 736 2 3 5

External Ids for ZNF736 Gene

Previous GeneCards Identifiers for ZNF736 Gene

  • GC00U922630
  • GC07P063767
  • GC07P060153

Summaries for ZNF736 Gene

GeneCards Summary for ZNF736 Gene

ZNF736 (Zinc Finger Protein 736) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF727.

UniProtKB/Swiss-Prot for ZNF736 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF736 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF736 Gene

Genomics for ZNF736 Gene

GeneHancer (GH) Regulatory Elements for ZNF736 Gene

Promoters and enhancers for ZNF736 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I064312 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 562.4 +6.6 6560 3.2 PKNOX1 SIN3A YY1 ZNF121 POLR2B ELK1 ZNF207 ATF7 FOS RUNX3 ZNF736 GTF2IP14 ENSG00000227113 YWHAEP1 ZNF727 GUSBP6 ZNF107 SEPHS1P1 GC07M064314 LOC105375322
GH07I064305 Promoter/Enhancer 1.7 FANTOM5 Ensembl ENCODE 550.8 -0.2 -228 2.6 HDGF ATF1 ZNF2 IRF4 YY1 ETS1 ZNF143 ATF7 RUNX3 SP3 GC07P064309 LOC105375322 ZNF736 PIR31902 GUSBP6 ZNF680 YWHAEP1 ZNF680P1 TRIM60P18 SEPHS1P1
GH07I064995 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 12.4 +694.4 694426 11.8 MLX DMAP1 YY1 E2F8 ZNF143 SP3 NFYC MEF2D SSRP1 RCOR2 ERV3-1 GTF2IP14 CCT6P3 INTS4P1 ZNF117 CCT6P1 VKORC1L1 ZNF736 ENSG00000227113 EEF1DP4
GH07I064562 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 11.7 +255.4 255442 1.8 PKNOX1 ATF1 ARID4B SIN3A DMAP1 ZNF2 ZNF48 YY1 ETS1 POLR2B ZNF680 ZNF107 CCT6P3 GTF2IP14 ZNF736 GABPAP ZNF117 LOC644387 BNIP3P42
GH07I064664 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 11.7 +359.0 358996 3.2 PKNOX1 SMAD1 ARID4B SIN3A DMAP1 YY1 POLR2B E2F8 ZNF207 ZNF143 ZNF107 CCT6P3 GTF2IP14 ZNF736 LOC441239 ERV3-1 SEPHS1P1 ZNF138 MIR6839
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF736 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZNF736 Gene

Genomic Locations for ZNF736 Gene
49,176 bases
Plus strand

Genomic View for ZNF736 Gene

Genes around ZNF736 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF736 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF736 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF736 Gene

Proteins for ZNF736 Gene

  • Protein details for ZNF736 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 736
    Protein Accession:

    Protein attributes for ZNF736 Gene

    427 amino acids
    Molecular mass:
    49868 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF736 Gene

Post-translational modifications for ZNF736 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF736 Gene

No data available for DME Specific Peptides for ZNF736 Gene

Domains & Families for ZNF736 Gene

Gene Families for ZNF736 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF736 Gene

Suggested Antigen Peptide Sequences for ZNF736 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF736: view

Function for ZNF736 Gene

Molecular function for ZNF736 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF736 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF736: view

Phenotypes for ZNF736 Gene

GenomeRNAi human phenotypes for ZNF736:
genes like me logo Genes that share phenotypes with ZNF736: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF736 Gene

Localization for ZNF736 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF736 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF736 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF736 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF736: view

Pathways & Interactions for ZNF736 Gene

SuperPathways for ZNF736 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF736: view

Pathways by source for ZNF736 Gene

2 Reactome pathways for ZNF736 Gene

Interacting Proteins for ZNF736 Gene

Gene Ontology (GO) - Biological Process for ZNF736 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF736: view

No data available for SIGNOR curated interactions for ZNF736 Gene

Drugs & Compounds for ZNF736 Gene

No Compound Related Data Available

Transcripts for ZNF736 Gene

mRNA/cDNA for ZNF736 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(8) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF736 Gene

Zinc finger protein 736:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF736 Gene

No ASD Table

Relevant External Links for ZNF736 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF736 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF736 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF736 Gene:


SOURCE GeneReport for Unigene cluster for ZNF736 Gene:

genes like me logo Genes that share expression patterns with ZNF736: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF736 Gene

Orthologs for ZNF736 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF736 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF736 33 34
  • 99.06 (n)
(Monodelphis domestica)
Mammalia -- 34
  • 43 (a)
-- 34
  • 28 (a)
(Mus musculus)
Mammalia Zfp85-rs1 34
  • 43 (a)
(Bos Taurus)
Mammalia -- 34
  • 39 (a)
(Canis familiaris)
Mammalia -- 34
  • 29 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 40 (a)
-- 34
  • 30 (a)
-- 34
  • 28 (a)
-- 34
  • 26 (a)
-- 34
  • 24 (a)
-- 34
  • 23 (a)
-- 34
  • 23 (a)
-- 34
  • 23 (a)
Species where no ortholog for ZNF736 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF736 Gene

Gene Tree for ZNF736 (if available)
Gene Tree for ZNF736 (if available)

Paralogs for ZNF736 Gene

(487) SIMAP similar genes for ZNF736 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF736: view

Variants for ZNF736 Gene

Sequence variations from dbSNP and Humsavar for ZNF736 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000100291 -- 64,353,055(+) C/T 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1000298872 -- 64,335,630(+) T/C intron_variant
rs1000358994 -- 64,330,225(+) T/C intron_variant
rs1000603300 -- 64,312,025(+) G/A/C upstream_transcript_variant
rs1000632256 -- 64,341,653(+) A/G genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF736 Gene

Variant ID Type Subtype PubMed ID
dgv1099e201 CNV deletion 23290073
dgv1108n67 CNV loss 20364138
dgv11415n54 CNV loss 21841781
dgv1212e199 CNV deletion 23128226
dgv240n111 CNV duplication 26073780
dgv6434n100 CNV loss 25217958
esv2422405 CNV duplication 17116639
esv2764000 CNV gain+loss 21179565
esv3410592 CNV insertion 20981092
esv3613414 CNV loss 21293372
esv3891131 CNV gain+loss 25118596
esv3891132 CNV gain 25118596
nsv1016645 CNV gain+loss 25217958
nsv1018445 CNV gain 25217958
nsv1018858 CNV loss 25217958
nsv1019909 CNV gain 25217958
nsv1137241 CNV deletion 24896259
nsv464515 CNV loss 19166990
nsv518721 CNV loss 19592680
nsv522412 CNV loss 19592680
nsv607304 CNV gain 21841781
nsv607309 CNV loss 21841781
nsv607310 CNV loss 21841781
nsv958455 CNV deletion 24416366
nsv966818 CNV duplication 23825009

Variation tolerance for ZNF736 Gene

Gene Damage Index Score: 11.33; 92.64% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF736 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF736 Gene

Disorders for ZNF736 Gene

Additional Disease Information for ZNF736

No disorders were found for ZNF736 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF736 Gene

Publications for ZNF736 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  3. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier LW … Wilson RK (Nature 2003) 4 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for ZNF736 Gene

Sources for ZNF736 Gene

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