Aliases for ZNF724 Gene

Aliases for ZNF724 Gene

  • Zinc Finger Protein 724 2 3 4 5
  • ZNF724P 3 4
  • Zinc Finger Protein 724 (Pseudogene) 2
  • Zinc Finger Protein 724, Pseudogene 2
  • Zinc Finger Protein 724 Pseudogene 2

External Ids for ZNF724 Gene

Previous HGNC Symbols for ZNF724 Gene

  • ZNF724P

Previous GeneCards Identifiers for ZNF724 Gene

  • GC19M023223
  • GC19M023276

Summaries for ZNF724 Gene

GeneCards Summary for ZNF724 Gene

ZNF724 (Zinc Finger Protein 724) is a Protein Coding gene. Among its related pathways are Gene Expression. An important paralog of this gene is ZNF681.

UniProtKB/Swiss-Prot Summary for ZNF724 Gene

Additional gene information for ZNF724 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF724 Gene

Genomics for ZNF724 Gene

GeneHancer (GH) Regulatory Elements for ZNF724 Gene

Promoters and enhancers for ZNF724 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J023249 Promoter/Enhancer 1.6 Ensembl ENCODE CraniofacialAtlas 500.7 +0.9 855 3.1 ZBTB40 ZNF217 SIN3A POLR2G SP1 ZFX POLR2A FOS GABPA SAP30 ZNF724 IPO5P1 ENSG00000269397 BNIP3P38 lnc-ZNF730-8 ENSG00000283201
GH19J023272 Promoter/Enhancer 1.7 Ensembl ENCODE CraniofacialAtlas 0.4 -23.1 -23111 3 ZNF217 EP300 POLR2G SP1 ZIC2 POLR2A ZBTB26 TGIF2 NFYB MXI1 IPO5P1 ENSG00000269107 ENSG00000283201 ENSG00000284428 ZNF724
GH19J023253 Enhancer 0.4 Ensembl 0.7 -3.8 -3811 2.4 POLR2A SPI1 GATA3 FOXA1 HLF IPO5P1 ENSG00000269397 ZNF724 ENSG00000283201
GH19J023243 Enhancer 0.2 FANTOM5 0.4 +7.1 7084 0.4 BNIP3P38 ZNF724 lnc-ZNF730-8 ENSG00000283201
GH19J023233 Enhancer 0.2 FANTOM5 0.4 +16.6 16590 0 BNIP3P38 lnc-ZNF730-8 piR-61357-002 ZNF724 ENSG00000283201
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF724 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF724

Genomic Locations for ZNF724 Gene

Genomic Locations for ZNF724 Gene
chr19:23,221,599-23,250,390
(GRCh38/hg38)
Size:
28,792 bases
Orientation:
Minus strand
chr19:23,404,401-23,433,192
(GRCh37/hg19)
Size:
28,792 bases
Orientation:
Minus strand

Genomic View for ZNF724 Gene

Genes around ZNF724 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF724 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF724 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF724 Gene

Proteins for ZNF724 Gene

  • Protein details for ZNF724 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MTY0-ZN724_HUMAN
    Recommended name:
    Zinc finger protein 724
    Protein Accession:
    A8MTY0
    Secondary Accessions:
    • B4DVU0

    Protein attributes for ZNF724 Gene

    Size:
    619 amino acids
    Molecular mass:
    71172 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF724 Gene

Post-translational modifications for ZNF724 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF724 Gene

No data available for DME Specific Peptides for ZNF724 Gene

Domains & Families for ZNF724 Gene

Gene Families for ZNF724 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF724 Gene

Suggested Antigen Peptide Sequences for ZNF724 Gene

GenScript: Design optimal peptide antigens:
  • Putative zinc finger protein 724 (ZN724_HUMAN)

Graphical View of Domain Structure for InterPro Entry

A8MTY0

UniProtKB/Swiss-Prot:

ZN724_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF724: view

Function for ZNF724 Gene

Molecular function for ZNF724 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF724 Gene

Gene Ontology (GO) - Molecular Function for ZNF724 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF724: view

Phenotypes for ZNF724 Gene

genes like me logo Genes that share phenotypes with ZNF724: view

miRNA for ZNF724 Gene

miRTarBase miRNAs that target ZNF724

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF724 Gene

Localization for ZNF724 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF724 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF724 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF724 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF724: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF724 Gene

Pathways & Interactions for ZNF724 Gene

PathCards logo

SuperPathways for ZNF724 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF724: view

Pathways by source for ZNF724 Gene

2 Reactome pathways for ZNF724 Gene

Interacting Proteins for ZNF724 Gene

;

Gene Ontology (GO) - Biological Process for ZNF724 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF724: view

No data available for SIGNOR curated interactions for ZNF724 Gene

Drugs & Compounds for ZNF724 Gene

No Compound Related Data Available

Transcripts for ZNF724 Gene

mRNA/cDNA for ZNF724 Gene

3 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF724 Gene

No ASD Table

Relevant External Links for ZNF724 Gene

GeneLoc Exon Structure for
ZNF724

Expression for ZNF724 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF724

Evidence on tissue expression from TISSUES for ZNF724 Gene

  • Spleen(4)
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF724 Gene

Orthologs for ZNF724 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF724 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF724P 31
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 31
  • 57 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp58 31
  • 53 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 53 (a)
ManyToMany
-- 31
  • 43 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 31
  • 42 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 31
  • 55 (a)
ManyToMany
-- 31
  • 47 (a)
ManyToMany
-- 31
  • 41 (a)
ManyToMany
-- 31
  • 39 (a)
ManyToMany
-- 31
  • 37 (a)
ManyToMany
-- 31
  • 36 (a)
ManyToMany
-- 31
  • 35 (a)
ManyToMany
-- 31
  • 30 (a)
ManyToMany
Species where no ortholog for ZNF724 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF724 Gene

ENSEMBL:
Gene Tree for ZNF724 (if available)
TreeFam:
Gene Tree for ZNF724 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF724: view image

Paralogs for ZNF724 Gene

Paralogs for ZNF724 Gene

genes like me logo Genes that share paralogs with ZNF724: view

Variants for ZNF724 Gene

Additional dbSNP identifiers (rs#s) for ZNF724 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF724 Gene

Variant ID Type Subtype PubMed ID
dgv138e55 CNV gain 17911159
dgv511e201 CNV deletion 23290073
esv2751784 CNV gain 17911159
esv2758750 CNV gain+loss 17122850
esv3643989 CNV gain 21293372
esv3643990 CNV loss 21293372
esv5233 OTHER inversion 18987735
nsv1057420 CNV gain 25217958
nsv579033 CNV loss 21841781
nsv579034 CNV gain 21841781
nsv817826 CNV gain 17921354
nsv833789 CNV gain+loss 17160897
nsv833790 CNV gain 17160897
nsv961201 CNV duplication 23825009
nsv9686 CNV gain+loss 18304495

Variation tolerance for ZNF724 Gene

Gene Damage Index Score: 1.02; 20.87% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF724 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF724

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF724 Gene

Disorders for ZNF724 Gene

Additional Disease Information for ZNF724

No disorders were found for ZNF724 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF724 Gene

Publications for ZNF724 Gene

  1. VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3 54
  2. An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations. (PMID: 29568061) Liu X … Varjosalo M (Nature communications 2018) 3 54
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 54
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 54
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 54

Products for ZNF724 Gene

Sources for ZNF724 Gene