Aliases for ZNF711 Gene
Aliases for ZNF711 Gene
External Ids for ZNF711 Gene
- HGNC: 13128
- Entrez Gene: 7552
- Ensembl: ENSG00000147180
- OMIM: 314990
- UniProtKB: Q9Y462
Previous HGNC Symbols for ZNF711 Gene
- ZNF6
Previous GeneCards Identifiers for ZNF711 Gene
- GC0XP084385
- GC0XP084498
- GC0XP078072
Summaries for ZNF711 Gene
-
This gene encodes a zinc finger protein of unknown function. It bears similarity to a zinc finger protein which acts as a transcriptional activator. This gene lies in a region of the X chromosome which has been associated with cognitive disability. [provided by RefSeq, Jul 2008]
GeneCards Summary for ZNF711 Gene
ZNF711 (Zinc Finger Protein 711) is a Protein Coding gene. Diseases associated with ZNF711 include Mental Retardation, X-Linked 97 and X-Linked Non-Specific Intellectual Disability. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is ZFX.
UniProtKB/Swiss-Prot for ZNF711 Gene
-
Transcription regulator required for brain development. Probably acts as a transcription factor that binds to the promoter of target genes and recruits PHF8 histone demethylase, leading to activate expression of genes involved in neuron development, such as KDM5C.
Additional gene information for ZNF711 Gene
- Monarch Initiative
- Search for ZNF711 at DataMed
- Search for ZNF711 at HumanCyc
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF711 Gene
Genomics for ZNF711 Gene
GeneHancer (GH) Regulatory Elements for ZNF711 Gene
Promoters and enhancers for ZNF711 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH0XI085243 | Promoter/Enhancer | 1.8 | EPDnew Ensembl ENCODE | 556 | +0.7 | 681 | 2.6 | PKNOX1 ATF1 SIN3A ZNF335 GLIS2 ZNF366 ATF7 CREM EGR2 CEBPB | ZNF711 LOC105369163 POF1B GC0XP084968 | |
| GH0XI085188 | Enhancer | 0.2 | FANTOM5 | 1.8 | -55.3 | -55252 | 0.2 | SATL1 ZNF711 ENSG00000276391 ENSG00000283446 LOC105369163 GC0XP084968 | ||
| GH0XI085373 | Promoter/Enhancer | 1 | EPDnew ENCODE | 0.1 | +133.4 | 133420 | 7.1 | SMAD1 POLR2A ATF7 ELF1 MLLT1 KLF4 ATF2 | POF1B ZNF711 GC0XP084968 | |
| GH0XI085357 | Enhancer | 0.5 | ENCODE | 0.1 | +115.4 | 115364 | 3.3 | SMARCE1 NCOA3 ZNF217 CTBP1 GATA3 RFX1 DPF2 | POF1B ZNF711 GC0XP084968 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around ZNF711 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for ZNF711 Gene
Genomic Locations for ZNF711 Gene
- chrX:85,243,820-85,273,362
- (GRCh38/hg38)
- Size:
- 29,543 bases
- Orientation:
- Plus strand
- chrX:84,498,997-84,528,368
- (GRCh37/hg19)
Genomic View for ZNF711 Gene
Genes around ZNF711 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xq21.1 by Ensembl
- Xq21.1 by Entrez Gene
- Xq21.1 by HGNC
ZNF711 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZNF711 Gene
Proteins for ZNF711 Gene
-
Protein details for ZNF711 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y462-ZN711_HUMAN
- Recommended name:
- Zinc finger protein 711
- Protein Accession:
- Q9Y462
- B4DSV4
- Q6NX42
- Q9Y4J6
Protein attributes for ZNF711 Gene
- Size:
- 761 amino acids
- Molecular mass:
- 86245 Da
- Quaternary structure:
-
- Interacts with PHF8.
- SequenceCaution:
-
- Sequence=BAG61766.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAA39837.2; Type=Frameshift; Positions=Several; Evidence={ECO:0000305}; Sequence=CAA39837.2; Type=Miscellaneous discrepancy; Note=Chimera.; Evidence={ECO:0000305};
Protein Expression for ZNF711 Gene
Post-translational modifications for ZNF711 Gene
Other Protein References for ZNF711 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- NP_001317503.1
- NP_068838.3
- XP_005262243.1
- XP_005262244.1
- XP_005262245.1
- XP_005262246.1
- XP_011529321.1
- XP_011529322.1
- XP_011529323.1
- XP_011529324.1
- XP_011529325.1
- XP_011529326.1
- XP_011529327.1
- XP_011529328.1
- XP_016885292.1
- XP_016885293.1
- XP_016885294.1
- XP_016885295.1
- XP_016885296.1
- XP_016885297.1
- XP_016885298.1
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for ZNF711
- Novus Biologicals Antibodies for ZNF711
-
Abcam antibodies for ZNF711
- Invitrogen Antibodies for ZNF711
- GeneTex ZNF711 antibody for ZNF711
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for ZNF711
- Origene Custom Protein Services for ZNF711
- Novus Biologicals proteins for ZNF711
- Search GeneTex for Proteins for ZNF711
Assay Products
No data available for DME Specific Peptides for ZNF711 Gene
Domains & Families for ZNF711 Gene
Gene Families for ZNF711 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ZNF711 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ZNF711 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9Y462- Family:
-
- Belongs to the krueppel C2H2-type zinc-finger protein family.
Function for ZNF711 Gene
Molecular function for ZNF711 Gene
- UniProtKB/Swiss-Prot Function:
- Transcription regulator required for brain development. Probably acts as a transcription factor that binds to the promoter of target genes and recruits PHF8 histone demethylase, leading to activate expression of genes involved in neuron development, such as KDM5C.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 20346720 |
| GO:0043565 | sequence-specific DNA binding | IDA | 20346720 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for ZNF711 Gene
- GenomeRNAi human phenotypes for ZNF711:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ZNF711
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ZNF711 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ZNF711 gene
- Search ViGene Biosciences for ZNF711
CRISPR Products
-
OriGene CRISPR knockouts for ZNF711
- genomics-online: gRNA clones - Search results for available znf711 gene related products
- Applied Biological Materials CRISPR for ZNF711
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF711
- GenScript: Design CRISPR guide RNA sequences for ZNF711
miRNA for ZNF711 Gene
- miRTarBase miRNAs that target ZNF711
-
- hsa-mir-335-5p (MIRT017955)
- hsa-mir-19b-3p (MIRT031177)
- hsa-mir-18a-5p (MIRT031317)
- hsa-mir-615-3p (MIRT040430)
- hsa-mir-151a-3p (MIRT043601)
- hsa-mir-218-5p (MIRT046981)
- hsa-mir-548c-3p (MIRT110174)
- hsa-mir-34a-3p (MIRT328117)
- hsa-mir-142-5p (MIRT328118)
- hsa-mir-559 (MIRT328119)
- hsa-mir-548b-5p (MIRT328120)
- hsa-mir-548a-5p (MIRT328121)
- hsa-mir-548c-5p (MIRT328122)
- hsa-mir-548d-5p (MIRT328123)
- hsa-mir-548j-5p (MIRT328124)
- hsa-mir-548k (MIRT328125)
- hsa-mir-548l (MIRT328126)
- hsa-mir-548h-5p (MIRT328127)
- hsa-mir-548i (MIRT328128)
- hsa-mir-3157-5p (MIRT328129)
- hsa-mir-548w (MIRT328130)
- hsa-mir-548y (MIRT328131)
- hsa-mir-548o-5p (MIRT328132)
- hsa-mir-548ab (MIRT328133)
- hsa-mir-548ad-5p (MIRT328134)
- hsa-mir-548ae-5p (MIRT328135)
- hsa-mir-548ak (MIRT328136)
- hsa-mir-548am-5p (MIRT328137)
- hsa-mir-548ap-5p (MIRT328138)
- hsa-mir-548aq-5p (MIRT328139)
- hsa-mir-548ar-5p (MIRT328140)
- hsa-mir-548as-5p (MIRT328141)
- hsa-mir-548au-5p (MIRT328142)
- hsa-mir-5590-3p (MIRT328143)
- hsa-mir-548av-5p (MIRT328144)
- hsa-mir-548ay-5p (MIRT328145)
- hsa-mir-8054 (MIRT328146)
- hsa-mir-548bb-5p (MIRT328147)
- hsa-mir-188-3p (MIRT328167)
- hsa-mir-5692a (MIRT328168)
- hsa-mir-5007-3p (MIRT367067)
- hsa-mir-5579-5p (MIRT367069)
- hsa-mir-4666b (MIRT367070)
- hsa-mir-5700 (MIRT367071)
- hsa-mir-802 (MIRT367101)
- hsa-mir-543 (MIRT367102)
- hsa-mir-3143 (MIRT367103)
- hsa-mir-95-5p (MIRT367106)
- hsa-mir-130a-3p (MIRT367107)
- hsa-mir-301a-3p (MIRT367108)
- hsa-mir-130b-3p (MIRT367109)
- hsa-mir-454-3p (MIRT367113)
- hsa-mir-301b-3p (MIRT367114)
- hsa-mir-3140-3p (MIRT367115)
- hsa-mir-3149 (MIRT367116)
- hsa-mir-4295 (MIRT367117)
- hsa-mir-3666 (MIRT367118)
- hsa-mir-297 (MIRT504969)
- hsa-mir-675-3p (MIRT504970)
- hsa-mir-5701 (MIRT504971)
- hsa-mir-6847-3p (MIRT504972)
- hsa-mir-6512-5p (MIRT504973)
- hsa-mir-511-5p (MIRT504974)
- hsa-mir-6830-3p (MIRT504975)
- hsa-mir-4691-3p (MIRT504976)
- hsa-mir-4803 (MIRT504977)
- hsa-mir-569 (MIRT564607)
- hsa-mir-551b-5p (MIRT564608)
- hsa-mir-5680 (MIRT571510)
- hsa-mir-212-3p (MIRT571511)
- hsa-mir-132-3p (MIRT571512)
Targeted motifs for ZNF711 Gene
HOMER Transcription Factor Regulatory Elements motif ZNF711
- Consensus sequence: AGGCCTAG Submotif: canonical Cell Type: SHSY5Y GEO ID: GSE20673
miRNA Products
- Search ViGene Biosciences for ZNF711
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF711
- Browse OriGene Inhibitory RNA Products For ZNF711
- genomics-online: shRNA clones - Search results for available znf711 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ZNF711 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for ZNF711
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ZNF711
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available znf711 gene related products
- orf clones - Search results for available znf711 gene related products
- Applied Biological Materials Clones for ZNF711
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for ZNF711
-
ViGene Biosciences adenoviral particle packaged cDNA for ZNF711 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ZNF711 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ZNF711 gene
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Animal Models and Transcription Factor Targets for ZNF711 Gene
Localization for ZNF711 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZNF711 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 5 |
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA | 20346720 |
| GO:0070062 | extracellular exosome | IDA,HDA | 23376485 |
Pathways & Interactions for ZNF711 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Gene Expression |
.48
|
|
Pathways by source for ZNF711 Gene
2 Reactome pathways for ZNF711 Gene
Interacting Proteins for ZNF711 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0045893 | positive regulation of transcription, DNA-templated | IMP | 20346720 |
No data available for SIGNOR curated interactions for ZNF711 Gene
Transcripts for ZNF711 Gene
mRNA/cDNA for ZNF711 Gene
- (21) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (54) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ZNF711 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ZNF711
- genomics-online: gRNA clones - Search results for available znf711 gene related products
- Applied Biological Materials CRISPR for ZNF711
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF711
- GenScript: Design CRISPR guide RNA sequences for ZNF711
miRNA Products
- Search ViGene Biosciences for ZNF711
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF711
- Browse OriGene Inhibitory RNA Products For ZNF711
- genomics-online: shRNA clones - Search results for available znf711 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ZNF711 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for ZNF711
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ZNF711
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available znf711 gene related products
- orf clones - Search results for available znf711 gene related products
- Applied Biological Materials Clones for ZNF711
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | · | 12c | ^ | 13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| SP4: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||||||||||||||||||
| SP9: |
Expression for ZNF711 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Cardiovascular System)
- Definitive Hematopoietic Stem Cells Definitive Yolk Sac
- Hematopoietic Stem Cells Hematopoietic Bone Marrow
-
Yolk Sac (Extraembryonic Tissues)
- Definitive Hematopoietic Stem Cells Definitive Yolk Sac
-
Eye (Sensory Organs)
- Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
-
Epithelial Cells
- Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
-
Mesoderm (Gastrulation Derivatives)
- Mesothelial Cells Hepatic Mesenchyme
-
Liver (Hepatobiliary System)
- Mesothelial Cells Hepatic Mesenchyme
-
Heart (Cardiovascular System)
- Cardiac Fibroblasts Myocardium
-
Fibroblasts
- Cardiac Fibroblasts Myocardium
-
Ovary (Reproductive System)
- XX Germ Cells Ovigerous Cord
-
Gonad
- XX Germ Cells Ovigerous Cord
mRNA differential expression in normal tissues according to GTEx for ZNF711 Gene
This gene is overexpressed in Testis (x5.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF711 Gene
NURSA nuclear receptor signaling pathways regulating expression of ZNF711 Gene:
ZNF711SOURCE GeneReport for Unigene cluster for ZNF711 Gene:
Hs.326801mRNA Expression by UniProt/SwissProt for ZNF711 Gene:
Q9Y462-ZN711_HUMAN
Tissue specificity:
Expressed in neural tissues.
Evidence on tissue expression from TISSUES for ZNF711 Gene
- Nervous system(4.6)
Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF711 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- digestive
- integumentary
- nervous
- reproductive
- respiratory
- skeletal muscle
- skeleton
- urinary
Regions:
Head and neck:
- brain
- cerebellum
- cheek
- chin
- cranial nerve
- ear
- eye
- eyelid
- face
- forehead
- head
- jaw
- lip
- mandible
- maxilla
- mouth
- nose
- outer ear
- salivary gland
- skull
- tooth
Thorax:
- lung
- rib
- rib cage
Pelvis:
- pelvis
- testicle
- urinary bladder
Limb:
- ankle
- digit
- elbow
- finger
- foot
- hand
- hip
- knee
- lower limb
- shoulder
- toe
- upper limb
- wrist
General:
- hair
- peripheral nerve
- peripheral nervous system
- skin
- spinal column
- vertebrae
Primer Products
-
OriGene qPCR primer pairs for ZNF711
-
OriGene qPCR primer pairs and template standards for ZNF711
- genomics-online: primer clones - Search results for available znf711 gene related products
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues and Protein tissue co-expression partners for ZNF711 Gene
Orthologs for ZNF711 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ZNF711 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | ZNF711 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | ZNF711 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Zfp711 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Zfp711 33 16 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ZNF711 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | ZNF711 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ZNF6 34 |
|
OneToOne | |
| ZNF711 33 |
|
||||
| lizard (Anolis carolinensis) |
Reptilia | ZNF711 34 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | znf711 33 34 |
|
- Species where no ortholog for ZNF711 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for ZNF711 Gene
(86) SIMAP similar genes for ZNF711 Gene using alignment to 4 proteins:
- ZFY
- ZFX
- ZNF55
- kr-znf3
- KLF4
- HZF16
- ZBTB17
- ZNF
- ZNF672
- ZNF500
- ZFS-5
- ZFS-2
- A-328A3.4
- ZSCAN21
- ZNF410
- HZF36
- smap-7
- ZNF56
- ZNF525
- ZNF234
- KLF1
- DKFZp686N0199
- ZFP64
- ZNF566
- ZNF22
- ZNF121
- REST
- PLZF
- DKFZp547H249
- zf30
- ZNF778
- ZNF72
- ZNF70
- ZNF570
- ZNF219
- ZFS-6
- KLF13
- HZF17
- DKFZp762K012
- DKFZp666C237
- ZNF78L1
- ZNF770
- ZNF697
- ZNF600
- ZNF436
- HZF30
- DKFZp686M04222
- DKFZp434J0650
- DKFZp434G1930
- ZNF664
- ZNF833P
- ZNF827
- ZNF808
- ZNF763
- ZNF720
- ZNF710
- ZNF660
- ZNF586
- ZNF492
- ZNF485
- ZNF32
- ZNF146
- ZNF117
- ZIC1
- ZFP1
- Nbla00121
- DKFZp570I0164
- CTCFL
- ZNF558
- ZNF883
- ZNF876P
- ZNF805
- ZNF791
- ZNF736
- ZNF718
- ZNF564
- ZNF501
- ZNF480
- ZNF345
- ZNF28
- ZNF263
- ZFS-3
- ZFS-1
- ZBTB47
- MST154
- DKFZp686B16128
Variants for ZNF711 Gene
| SNP ID | Clin | Chr 0X pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1057516011 | uncertain-significance, Non-syndromic X-linked intellectual disability | 85,244,148(+) | A/GGCGGCGGCG | 5_prime_UTR_variant, genic_upstream_transcript_variant | |
| rs1057516012 | uncertain-significance, Non-syndromic X-linked intellectual disability | 85,244,157(+) | GG/GGG | 5_prime_UTR_variant, genic_upstream_transcript_variant | |
| rs1057516013 | uncertain-significance, Non-syndromic X-linked intellectual disability | 85,245,958(+) | G/T | 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1057516014 | uncertain-significance, Non-syndromic X-linked intellectual disability | 85,271,566(+) | C/T | coding_sequence_variant, missense_variant | |
| rs1057516016 | uncertain-significance, Non-syndromic X-linked intellectual disability | 85,272,016(+) | A/G | 3_prime_UTR_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2466752 | CNV | deletion | 19546169 |
| esv2740275 | CNV | deletion | 23290073 |
| esv3559049 | CNV | deletion | 23714750 |
Residual Variation Intolerance Score:
18.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.72;
15.32% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ZNF711 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF711 Gene
Disorders for ZNF711 Gene
(3) MalaCards diseases for ZNF711 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| mental retardation, x-linked 97 |
|
|
| x-linked non-specific intellectual disability |
|
|
| allan-herndon-dudley syndrome |
|
|
Search ZNF711 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
ZN711_HUMAN- Mental retardation, X-linked 97 (MRX97) [MIM:300803]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. {ECO:0000269 PubMed:19377476, ECO:0000269 PubMed:27993705}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for ZNF711
No data available for Genatlas for ZNF711 Gene
Publications for ZNF711 Gene
- A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation. (PMID: 19377476) Tarpey PS … Stratton MR (Nature genetics 2009) 2 3 4 58
- Mutations in two large pedigrees highlight the role of ZNF711 in X-linked intellectual disability. (PMID: 27993705) van der Werf IM … Kooy RF (Gene 2017) 3 4 58
- A functional link between the histone demethylase PHF8 and the transcription factor ZNF711 in X-linked mental retardation. (PMID: 20346720) Kleine-Kohlbrecher D … Helin K (Molecular cell 2010) 3 4 58
- The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
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Sources for ZNF711 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
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- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
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- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
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