Aliases for ZNF710 Gene

Aliases for ZNF710 Gene

  • Zinc Finger Protein 710 2 3 4 5

External Ids for ZNF710 Gene

Previous GeneCards Identifiers for ZNF710 Gene

  • GC15P088346
  • GC15P090544
  • GC15P066721

Summaries for ZNF710 Gene

GeneCards Summary for ZNF710 Gene

ZNF710 (Zinc Finger Protein 710) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and transcription coregulator activity. An important paralog of this gene is ZNF366.

UniProtKB/Swiss-Prot Summary for ZNF710 Gene

Additional gene information for ZNF710 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF710 Gene

Genomics for ZNF710 Gene

GeneHancer (GH) Regulatory Elements for ZNF710 Gene

Promoters and enhancers for ZNF710 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J090057 Enhancer 1.6 FANTOM5 ENCODE CraniofacialAtlas dbSUPER 26.6 +62.8 62810 8.2 NRF1 USF1 SP1 ZNF10 EP300 ZIC2 POLR2A ZBTB11 AFF1 RELA ZNF710 IQGAP1 IDH2 MESP1 ENSG00000228998 AP3S2 SEMA4B CIB1 ANPEP piR-60872
GH15J090032 Promoter/Enhancer 2 FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 19.9 +37.9 37929 8.3 EP300 ZNF217 SP1 NCOR1 ZFX ZNF639 ZIC2 TCF7 AFF1 KLF4 ZNF710 IQGAP1 VPS33B AP3S2 SEMA4B ANPEP ENSG00000273691 piR-60872
GH15J090019 Promoter/Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 23.9 +21.1 21148 1.7 NR2F2 CTCF SPI1 FOS ADNP GATA2 VEZF1 MAX EGR1 AGO2 RF00017-1891 IQGAP1 ZNF710 MESP1 ANPEP CIB1 AP3S2 MIR3174
GH15J090028 Promoter/Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 18.9 +31.3 31279 4.4 SP1 RCOR1 TGIF2 POLR2A RBM25 FOXA2 BCL11A NR2F2 RELA TCF12 IQGAP1 ZNF710 NGRN ENSG00000228998 AP3S2 SEMA4B ANPEP ENSG00000273691 piR-60872
GH15J089780 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 14.3 -215.9 -215946 6.6 ZNF217 POLR2G NCOR1 GTF2E2 TEAD4 ZBTB11 REST KLF4 RELA CUX1 HSALNG0108074 MESP1 ZNF710 MFGE8 CRTC3 HAPLN3 WDR93 MESP2 PEX11A CIB1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF710 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF710

Top Transcription factor binding sites by QIAGEN in the ZNF710 gene promoter:
  • AML1a
  • ATF-2
  • CRE-BP1
  • E47
  • FOXI1
  • GATA-1
  • HEN1
  • HFH-3
  • STAT3
  • Tal-1

Genomic Locations for ZNF710 Gene

Genomic Locations for ZNF710 Gene
83,161 bases
Plus strand
80,815 bases
Plus strand

Genomic View for ZNF710 Gene

Genes around ZNF710 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF710 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF710 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF710 Gene

Proteins for ZNF710 Gene

  • Protein details for ZNF710 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 710
    Protein Accession:
    Secondary Accessions:
    • A0AVS3
    • Q6ZMK9
    • Q8NDU0

    Protein attributes for ZNF710 Gene

    664 amino acids
    Molecular mass:
    74461 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF710 Gene

Post-translational modifications for ZNF710 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF710 Gene

Domains & Families for ZNF710 Gene

Gene Families for ZNF710 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF710 Gene


Suggested Antigen Peptide Sequences for ZNF710 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 710 (ZN710_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF710: view

Function for ZNF710 Gene

Molecular function for ZNF710 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF710 Gene

Gene Ontology (GO) - Molecular Function for ZNF710 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF710: view
genes like me logo Genes that share phenotypes with ZNF710: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF710 Gene

Localization for ZNF710 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF710 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF710 gene
Compartment Confidence
nucleus 4
cytosol 3
peroxisome 0

Subcellular locations from the

Human Protein Atlas (HPA)
  • Mitochondria (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF710 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA 21873635
genes like me logo Genes that share ontologies with ZNF710: view

Pathways & Interactions for ZNF710 Gene

PathCards logo

SuperPathways for ZNF710 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF710: view

Pathways by source for ZNF710 Gene

2 Reactome pathways for ZNF710 Gene

Interacting Proteins for ZNF710 Gene


Gene Ontology (GO) - Biological Process for ZNF710 Gene


No data available for SIGNOR curated interactions for ZNF710 Gene

Drugs & Compounds for ZNF710 Gene

No Compound Related Data Available

Transcripts for ZNF710 Gene

mRNA/cDNA for ZNF710 Gene

7 NCBI additional mRNA sequence :
5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF710 Gene

No ASD Table

Relevant External Links for ZNF710 Gene

GeneLoc Exon Structure for

Expression for ZNF710 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF710 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF710 Gene

This gene is overexpressed in Pancreas (x4.2).

Protein differential expression in normal tissues from HIPED for ZNF710 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF710 Gene

Protein tissue co-expression partners for ZNF710 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF710

SOURCE GeneReport for Unigene cluster for ZNF710 Gene:


Evidence on tissue expression from TISSUES for ZNF710 Gene

  • Spleen(4.2)
  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZNF710: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF710 Gene

Orthologs for ZNF710 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ZNF710 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF710 31 30
  • 99.4 (n)
(Canis familiaris)
Mammalia ZNF710 31 30
  • 92.01 (n)
(Bos Taurus)
Mammalia ZNF710 31 30
  • 90.91 (n)
(Rattus norvegicus)
Mammalia Zfp710 30
  • 89.04 (n)
(Mus musculus)
Mammalia Zfp710 17 31 30
  • 88.91 (n)
(Monodelphis domestica)
Mammalia ZNF710 31
  • 82 (a)
(Gallus gallus)
Aves ZNF710 31 30
  • 80.3 (n)
(Anolis carolinensis)
Reptilia ZNF710 31
  • 67 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia znf710 30
  • 68.54 (n)
(Danio rerio)
Actinopterygii znf710a 31 30
  • 71.03 (n)
ZNF710 (1 of 2) 31
  • 48 (a)
wufi04b07 30
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.9921 30
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes PZF1 33 31
  • 22 (a)
Species where no ortholog for ZNF710 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF710 Gene

Gene Tree for ZNF710 (if available)
Gene Tree for ZNF710 (if available)
Evolutionary constrained regions (ECRs) for ZNF710: view image

Paralogs for ZNF710 Gene

Paralogs for ZNF710 Gene

(303) SIMAP similar genes for ZNF710 Gene using alignment to 4 proteins:

  • ZN710_HUMAN
genes like me logo Genes that share paralogs with ZNF710: view

Variants for ZNF710 Gene

Additional dbSNP identifiers (rs#s) for ZNF710 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF710 Gene

Variant ID Type Subtype PubMed ID
dgv112e55 CNV gain 17911159
esv2760054 CNV gain 17122850
esv3569864 CNV gain 25503493
esv3581814 CNV loss 25503493
esv3637210 CNV loss 21293372
esv3637211 CNV gain 21293372
esv3637212 CNV loss 21293372
esv997696 CNV deletion 20482838
nsv1071235 CNV deletion 25765185
nsv1121901 CNV deletion 24896259
nsv827430 CNV loss 20364138
nsv94745 CNV deletion 16902084

Variation tolerance for ZNF710 Gene

Residual Variation Intolerance Score: 48.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.45; 43.15% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF710 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF710 Gene

Disorders for ZNF710 Gene

Additional Disease Information for ZNF710

No disorders were found for ZNF710 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF710 Gene

Publications for ZNF710 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54
  3. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 54
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 54
  5. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 54

Products for ZNF710 Gene

Sources for ZNF710 Gene