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Aliases for ZNF705G Gene

Aliases for ZNF705G Gene

  • Zinc Finger Protein 705G 2 3 5

External Ids for ZNF705G Gene

Previous GeneCards Identifiers for ZNF705G Gene

  • GC08M007203
  • GC08M007205
  • GC08M006904

Summaries for ZNF705G Gene

GeneCards Summary for ZNF705G Gene

ZNF705G (Zinc Finger Protein 705G) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF705A.

UniProtKB/Swiss-Prot for ZNF705G Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF705G Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF705G Gene

Genomics for ZNF705G Gene

GeneHancer (GH) Regulatory Elements for ZNF705G Gene

Promoters and enhancers for ZNF705G Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08I007385 Promoter 0.5 EPDnew 550.8 +0.0 2 0.1 ZNF705G DEFB108C
GH08I007354 Promoter/Enhancer 1.4 Ensembl ENCODE 0.3 +30.3 30253 1.4 RB1 KLF17 ZNF76 ZNF2 KLF5 RAD21 ZNF335 GLIS2 ZNF207 ZNF143 FAM66B MCPH1 FAM86B3P LOC402329 ZNF705G
GH08I007389 Enhancer 0.4 ENCODE dbSUPER 0.8 -4.6 -4593 0.5 ZNF705G DEFB4B
GH08I007394 Enhancer 0.8 Ensembl ENCODE dbSUPER 0.4 -9.1 -9143 1.4 CEBPG FOXA1 ENSG00000271743 ZNF705G DEFB4B
GH08I007397 Enhancer 0.7 Ensembl dbSUPER 0.4 -12.4 -12443 0.4 CTCF ZNF654 RB1 ZSCAN5C SMC3 REST RAD21 ZNF705G DEFB4B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF705G on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF705G gene promoter:

Genomic Locations for ZNF705G Gene

Genomic Locations for ZNF705G Gene
30,042 bases
Minus strand

Genomic View for ZNF705G Gene

Genes around ZNF705G on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF705G Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF705G Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF705G Gene

Proteins for ZNF705G Gene

  • Protein details for ZNF705G Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative zinc finger protein 705G
    Protein Accession:

    Protein attributes for ZNF705G Gene

    300 amino acids
    Molecular mass:
    34765 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF705G Gene

Post-translational modifications for ZNF705G Gene

No Post-translational modifications

Other Protein References for ZNF705G Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF705G Gene

Domains & Families for ZNF705G Gene

Gene Families for ZNF705G Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF705G Gene

Suggested Antigen Peptide Sequences for ZNF705G Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF705G: view

Function for ZNF705G Gene

Molecular function for ZNF705G Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF705G Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF705G: view

Animal Model Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF705G Gene

Localization for ZNF705G Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF705G Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF705G gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF705G Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF705G: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF705G Gene

Pathways & Interactions for ZNF705G Gene

SuperPathways for ZNF705G Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF705G: view

Pathways by source for ZNF705G Gene

2 Reactome pathways for ZNF705G Gene

Interacting Proteins for ZNF705G Gene

Gene Ontology (GO) - Biological Process for ZNF705G Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF705G: view

No data available for SIGNOR curated interactions for ZNF705G Gene

Drugs & Compounds for ZNF705G Gene

No Compound Related Data Available

Transcripts for ZNF705G Gene

mRNA/cDNA for ZNF705G Gene

(3) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF705G Gene

Zinc finger protein 705G:
Representative Sequences:

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF705G Gene

No ASD Table

Relevant External Links for ZNF705G Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF705G Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF705G Gene

mRNA differential expression in normal tissues according to GTEx for ZNF705G Gene

This gene is overexpressed in Testis (x40.1).

NURSA nuclear receptor signaling pathways regulating expression of ZNF705G Gene:


SOURCE GeneReport for Unigene cluster for ZNF705G Gene:

genes like me logo Genes that share expression patterns with ZNF705G: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF705G Gene

Orthologs for ZNF705G Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF705G Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF705G 33 34
  • 97.89 (n)
(Bos Taurus)
Mammalia ZNF705A 34
  • 54 (a)
-- 34
  • 27 (a)
(Canis familiaris)
Mammalia -- 34
  • 54 (a)
Species where no ortholog for ZNF705G was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF705G Gene

Gene Tree for ZNF705G (if available)
Gene Tree for ZNF705G (if available)

Paralogs for ZNF705G Gene

Paralogs for ZNF705G Gene

(245) SIMAP similar genes for ZNF705G Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF705G: view

Variants for ZNF705G Gene

Sequence variations from dbSNP and Humsavar for ZNF705G Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs3989699 benign, not specified 7,361,099(-) C/G intron_variant
rs1000260179 -- 7,365,646(-) A/T genic_upstream_transcript_variant, intron_variant
rs1000396493 -- 7,366,297(-) G/T genic_upstream_transcript_variant, intron_variant
rs1000888004 -- 7,356,899(-) G/A downstream_transcript_variant
rs1001931488 -- 7,362,771(-) C/A/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF705G Gene

Variant ID Type Subtype PubMed ID
esv3616114 CNV loss 21293372
esv3584573 CNV gain 24956385
esv33606 CNV gain+loss 17666407
esv2764098 CNV gain+loss 21179565
esv2761169 CNV gain+loss 21179565
esv2759589 CNV gain+loss 17122850
esv21583 CNV gain+loss 19812545
dgv6927n100 CNV gain+loss 25217958
dgv6926n100 CNV loss 25217958
dgv6925n100 CNV gain 25217958
dgv6924n100 CNV loss 25217958
dgv6923n100 CNV gain+loss 25217958
dgv6922n100 CNV gain+loss 25217958
dgv6921n100 CNV loss 25217958
dgv6920n100 CNV gain 25217958
dgv6919n100 CNV gain+loss 25217958
dgv6918n100 CNV gain 25217958
dgv6917n100 CNV loss 25217958
dgv6916n100 CNV gain+loss 25217958
dgv6915n100 CNV gain 25217958
dgv6914n100 CNV gain+loss 25217958
dgv6913n100 CNV gain 25217958
dgv6912n100 CNV loss 25217958
dgv6911n100 CNV loss 25217958
dgv6910n100 CNV gain+loss 25217958
dgv6909n100 CNV gain 25217958
dgv6908n100 CNV gain 25217958
dgv6907n100 CNV loss 25217958
dgv6906n100 CNV gain 25217958
dgv6905n100 CNV gain 25217958
dgv6904n100 CNV gain 25217958
dgv6903n100 CNV loss 25217958
dgv6902n100 CNV gain 25217958
dgv6901n100 CNV gain+loss 25217958
dgv6900n100 CNV gain+loss 25217958
dgv6899n100 CNV gain 25217958
dgv6898n100 CNV loss 25217958
dgv6897n100 CNV gain 25217958
dgv6896n100 CNV gain+loss 25217958
dgv6895n100 CNV loss 25217958
dgv6894n100 CNV gain+loss 25217958
dgv6893n100 CNV gain 25217958
dgv6892n100 CNV loss 25217958
dgv6891n100 CNV gain+loss 25217958
dgv6890n100 CNV gain 25217958
dgv6889n100 CNV loss 25217958
dgv6888n100 CNV gain+loss 25217958
dgv6887n100 CNV loss 25217958
dgv6885n100 CNV gain 25217958
dgv6884n100 CNV gain 25217958
dgv6882n100 CNV gain 25217958
dgv6879n100 CNV gain 25217958
dgv6878n100 CNV gain 25217958
dgv3760n106 CNV duplication 24896259
dgv2035e212 CNV gain 25503493
dgv138n17 CNV loss 16327808
dgv1365e214 CNV gain 21293372
dgv11914n54 CNV gain 21841781
dgv11913n54 CNV gain 21841781
dgv11912n54 CNV loss 21841781
dgv11911n54 CNV loss 21841781
nsv515968 CNV gain+loss 19592680
nsv510977 OTHER complex 20534489
nsv471650 CNV gain+loss 15918152
nsv438033 CNV loss 16468122
nsv428194 CNV gain+loss 18775914
nsv1161711 OTHER complex 26073780
nsv1161710 CNV deletion 26073780
nsv1161709 CNV duplication 26073780
nsv1078037 CNV duplication 25765185
nsv1032847 CNV loss 25217958
nsv1031577 CNV gain 25217958
nsv1028208 CNV loss 25217958
nsv1027709 CNV gain+loss 25217958
nsv1026835 CNV gain+loss 25217958
nsv1026778 CNV gain 25217958
nsv1023986 CNV loss 25217958
nsv1017696 CNV gain+loss 25217958
esv996398 CNV gain 20482838
esv3891324 CNV gain 25118596
esv3891318 CNV gain 25118596
esv3616116 CNV loss 21293372
nsv971277 CNV duplication 23825009
nsv831225 CNV loss 17160897
nsv831224 CNV gain+loss 17160897
nsv831223 CNV loss 17160897
nsv8281 CNV gain+loss 18304495
nsv821656 CNV gain 15273396
nsv610044 CNV gain 21841781
nsv610041 CNV loss 21841781

Variation tolerance for ZNF705G Gene

Gene Damage Index Score: 2.65; 45.70% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF705G Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF705G Gene

Disorders for ZNF705G Gene

Additional Disease Information for ZNF705G

No disorders were found for ZNF705G Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF705G Gene

Publications for ZNF705G Gene

  1. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C … Lander ES (Nature 2006) 3 4 58
  2. Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? (PMID: 23314748) Nathan JA … Goldberg AL (The EMBO journal 2013) 3 58

Products for ZNF705G Gene

Sources for ZNF705G Gene

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