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Aliases for ZNF705E Gene

Aliases for ZNF705E Gene

  • Zinc Finger Protein 705E 2 3 5

External Ids for ZNF705E Gene

Previous GeneCards Identifiers for ZNF705E Gene

  • GC11U900944
  • GC11M071525

Summaries for ZNF705E Gene

GeneCards Summary for ZNF705E Gene

ZNF705E (Zinc Finger Protein 705E) is a Protein Coding gene. Among its related pathways are Gene Expression. An important paralog of this gene is ZNF705A.

UniProtKB/Swiss-Prot for ZNF705E Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF705E Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF705E Gene

Genomics for ZNF705E Gene

GeneHancer (GH) Regulatory Elements for ZNF705E Gene

Promoters and enhancers for ZNF705E Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I072430 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 107.2 -611.4 -611379 4.7 ZFP64 DMAP1 YY1 ZNF213 E2F8 ZNF143 SP3 ZC3H11A ZNF610 ZNF585B CLPB NUMA1 LOC100128494 ZNF705E RNF121 IL18BP NADSYN1 ENSG00000248671 ARHGEF17 FAM86C1
GH11I071927 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 32.2 -108.3 -108286 5.5 HDGF HNRNPUL1 PKNOX1 CLOCK FOXA2 SMAD1 ARNT ARID4B SIN3A FEZF1 RNF121 LOC100133315 NUMA1 LOC100128494 NADSYN1 ZNF705E IL18BP FAM86C1 ENSG00000255843 LRTOMT
GH11I072098 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 14 -280.3 -280261 6 HDGF PKNOX1 CLOCK SMAD1 FOXA2 MLX ARNT ARID4B SIN3A DMAP1 LAMTOR1 FAM86C1 NUMA1 LOC100128494 LRTOMT ZNF705E RNF121 IL18BP OR7E128P ENSG00000204971
GH11I072642 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 13.8 -821.5 -821455 1.6 PKNOX1 CLOCK ATF1 SIN3A ZNF2 GLIS2 ARID2 ZNF143 FOS ATF7 PDE2A LOC105369379 NUMA1 ZNF705E RNF121 LOC100128494 GC11P072622
GH11I072724 Enhancer 1.3 Ensembl ENCODE dbSUPER 22.2 -903.8 -903789 1.7 ARNT ARID4B SIN3A ARID2 ZNF143 RUNX3 DEK RXRA NCOA1 REST ARAP1 NUMA1 ZNF705E FAM86C1 LOC100128494 IL18BP RNF121 RPS12P20 PIR40050
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF705E on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZNF705E Gene

Genomic Locations for ZNF705E Gene
chr11:71,814,045-71,821,548
(GRCh38/hg38)
Size:
7,504 bases
Orientation:
Minus strand
chr11:71,525,091-71,532,594
(GRCh37/hg19)

Genomic View for ZNF705E Gene

Genes around ZNF705E on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF705E Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF705E Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF705E Gene

Proteins for ZNF705E Gene

  • Protein details for ZNF705E Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MWA4-Z705E_HUMAN
    Recommended name:
    Putative zinc finger protein 705E
    Protein Accession:
    A8MWA4

    Protein attributes for ZNF705E Gene

    Size:
    302 amino acids
    Molecular mass:
    34897 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF705E Gene

Post-translational modifications for ZNF705E Gene

No Post-translational modifications

Other Protein References for ZNF705E Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF705E Gene

Domains & Families for ZNF705E Gene

Gene Families for ZNF705E Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF705E Gene

Suggested Antigen Peptide Sequences for ZNF705E Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A8MWA4

UniProtKB/Swiss-Prot:

Z705E_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF705E: view

Function for ZNF705E Gene

Molecular function for ZNF705E Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF705E Gene

Gene Ontology (GO) - Molecular Function for ZNF705E Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF705E: view

Phenotypes for ZNF705E Gene

GenomeRNAi human phenotypes for ZNF705E:
genes like me logo Genes that share phenotypes with ZNF705E: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF705E Gene

Localization for ZNF705E Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF705E Gene

Gene Ontology (GO) - Cellular Components for ZNF705E Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF705E: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for ZNF705E Gene

Pathways & Interactions for ZNF705E Gene

SuperPathways for ZNF705E Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF705E: view

Pathways by source for ZNF705E Gene

2 Reactome pathways for ZNF705E Gene

Interacting Proteins for ZNF705E Gene

Gene Ontology (GO) - Biological Process for ZNF705E Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF705E: view

No data available for SIGNOR curated interactions for ZNF705E Gene

Drugs & Compounds for ZNF705E Gene

No Compound Related Data Available

Transcripts for ZNF705E Gene

mRNA/cDNA for ZNF705E Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF705E Gene

No ASD Table

Relevant External Links for ZNF705E Gene

GeneLoc Exon Structure for
ZNF705E
ECgene alternative splicing isoforms for
ZNF705E

Expression for ZNF705E Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF705E Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF705E Gene:

ZNF705E
genes like me logo Genes that share expression patterns with ZNF705E: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF705E Gene

Orthologs for ZNF705E Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ZNF705E Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF705E 33
  • 98.67 (n)
Species where no ortholog for ZNF705E was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF705E Gene

ENSEMBL:
Gene Tree for ZNF705E (if available)
TreeFam:
Gene Tree for ZNF705E (if available)

Paralogs for ZNF705E Gene

Paralogs for ZNF705E Gene

(263) SIMAP similar genes for ZNF705E Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF705E: view

Variants for ZNF705E Gene

Sequence variations from dbSNP and Humsavar for ZNF705E Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000209547 -- 71,813,569(-) C/T downstream_transcript_variant
rs1000373200 -- 71,823,230(-) T/C upstream_transcript_variant
rs1000405837 -- 71,822,974(-) T/C upstream_transcript_variant
rs10008349 -- 71,818,975(-) G/T intron_variant
rs1001252657 -- 71,817,256(-) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF705E Gene

Variant ID Type Subtype PubMed ID
nsv972041 CNV duplication 23825009
nsv8837 CNV gain+loss 18304495
nsv428262 CNV gain+loss 18775914
nsv1045511 CNV loss 25217958
esv3892025 CNV gain 25118596
esv2761682 CNV gain 21179565
esv2760190 CNV loss 21179565
esv2759836 CNV gain+loss 17122850
esv2744758 CNV deletion 23290073
esv25167 CNV gain 19812545
dgv223e199 CNV deletion 23128226
dgv1224n100 CNV gain 25217958
dgv1223n100 CNV gain 25217958
dgv1222n100 CNV gain 25217958

Additional Variant Information for ZNF705E Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF705E

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ZNF705E Gene

Disorders for ZNF705E Gene

Additional Disease Information for ZNF705E

No disorders were found for ZNF705E Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF705E Gene

Publications for ZNF705E Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 3 4 58

Products for ZNF705E Gene

Sources for ZNF705E Gene

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