Aliases for ZNF705E Gene

Aliases for ZNF705E Gene

  • Zinc Finger Protein 705E 2 3 5
  • Putative Zinc Finger Protein 705E 3 4
  • ZNF705E 5

External Ids for ZNF705E Gene

Previous GeneCards Identifiers for ZNF705E Gene

  • GC11U900944
  • GC11M071525

Summaries for ZNF705E Gene

GeneCards Summary for ZNF705E Gene

ZNF705E (Zinc Finger Protein 705E) is a Protein Coding gene. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. An important paralog of this gene is ZNF705A.

UniProtKB/Swiss-Prot Summary for ZNF705E Gene

Additional gene information for ZNF705E Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF705E Gene

Genomics for ZNF705E Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZNF705E Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF705E on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF705E

Genomic Locations for ZNF705E Gene

Genomic Locations for ZNF705E Gene
chr11:71,814,045-71,821,548
(GRCh38/hg38)
Size:
7,504 bases
Orientation:
Minus strand
chr11:71,525,091-71,532,594
(GRCh37/hg19)
Size:
7,504 bases
Orientation:
Minus strand

Genomic View for ZNF705E Gene

Genes around ZNF705E on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF705E Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF705E Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF705E Gene

Proteins for ZNF705E Gene

  • Protein details for ZNF705E Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MWA4-Z705E_HUMAN
    Recommended name:
    Putative zinc finger protein 705E
    Protein Accession:
    A8MWA4
    Secondary Accessions:
    • A0A1W2PRR0

    Protein attributes for ZNF705E Gene

    Size:
    300 amino acids
    Molecular mass:
    34697 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF705E Gene

Post-translational modifications for ZNF705E Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF705E Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF705E Gene

Domains & Families for ZNF705E Gene

Gene Families for ZNF705E Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF705E Gene

Suggested Antigen Peptide Sequences for ZNF705E Gene

GenScript: Design optimal peptide antigens:
  • Putative zinc finger protein 705E (Z705E_HUMAN)

Graphical View of Domain Structure for InterPro Entry

A8MWA4

UniProtKB/Swiss-Prot:

Z705E_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF705E: view

Function for ZNF705E Gene

Molecular function for ZNF705E Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF705E Gene

Gene Ontology (GO) - Molecular Function for ZNF705E Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0003700 DNA-binding transcription factor activity IBA 21873635
GO:0043565 sequence-specific DNA binding IBA 21873635
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF705E: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF705E

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF705E Gene

Localization for ZNF705E Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF705E Gene

Gene Ontology (GO) - Cellular Components for ZNF705E Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF705E: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for ZNF705E Gene

Pathways & Interactions for ZNF705E Gene

genes like me logo Genes that share pathways with ZNF705E: view

Pathways by source for ZNF705E Gene

2 Reactome pathways for ZNF705E Gene
1 KEGG pathway for ZNF705E Gene

Interacting Proteins for ZNF705E Gene

Gene Ontology (GO) - Biological Process for ZNF705E Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF705E: view

No data available for SIGNOR curated interactions for ZNF705E Gene

Drugs & Compounds for ZNF705E Gene

No Compound Related Data Available

Transcripts for ZNF705E Gene

mRNA/cDNA for ZNF705E Gene

1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF705E

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF705E Gene

No ASD Table

Relevant External Links for ZNF705E Gene

GeneLoc Exon Structure for
ZNF705E

Expression for ZNF705E Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF705E Gene

genes like me logo Genes that share expression patterns with ZNF705E: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF705E Gene

Orthologs for ZNF705E Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ZNF705E Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ZNF705E 30
  • 98.67 (n)
Species where no ortholog for ZNF705E was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for ZNF705E Gene

ENSEMBL:
Gene Tree for ZNF705E (if available)
TreeFam:
Gene Tree for ZNF705E (if available)

Paralogs for ZNF705E Gene

(263) SIMAP similar genes for ZNF705E Gene using alignment to 1 proteins:

  • Z705E_HUMAN
genes like me logo Genes that share paralogs with ZNF705E: view

Variants for ZNF705E Gene

Additional dbSNP identifiers (rs#s) for ZNF705E Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF705E Gene

Variant ID Type Subtype PubMed ID
dgv1222n100 CNV gain 25217958
dgv1223n100 CNV gain 25217958
dgv1224n100 CNV gain 25217958
dgv223e199 CNV deletion 23128226
esv25167 CNV gain 19812545
esv2744758 CNV deletion 23290073
esv2759836 CNV gain+loss 17122850
esv2760190 CNV loss 21179565
esv2761682 CNV gain 21179565
esv3892025 CNV gain 25118596
nsv1045511 CNV loss 25217958
nsv428262 CNV gain+loss 18775914
nsv8837 CNV gain+loss 18304495
nsv972041 CNV duplication 23825009

Additional Variant Information for ZNF705E Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF705E

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for ZNF705E Gene

Disorders for ZNF705E Gene

No disorders were found for ZNF705E Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF705E Gene

Publications for ZNF705E Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 3 4
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for ZNF705E Gene

Sources for ZNF705E Gene