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Aliases for ZNF705D Gene

Aliases for ZNF705D Gene

  • Zinc Finger Protein 705D 2 3 5
  • Putative Zinc Finger Protein 705C 3
  • Zinc Finger Protein 705C 3
  • ZNF705C 3

External Ids for ZNF705D Gene

Previous GeneCards Identifiers for ZNF705D Gene

  • GC08U900805
  • GC08P011985
  • GC08P011946

Summaries for ZNF705D Gene

GeneCards Summary for ZNF705D Gene

ZNF705D (Zinc Finger Protein 705D) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF705B.

UniProtKB/Swiss-Prot for ZNF705D Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF705D Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF705D Gene

Genomics for ZNF705D Gene

GeneHancer (GH) Regulatory Elements for ZNF705D Gene

Top Transcription factor binding sites by QIAGEN in the ZNF705D gene promoter:

Genomic Locations for ZNF705D Gene

Genomic Locations for ZNF705D Gene
26,179 bases
Plus strand

Genomic View for ZNF705D Gene

Genes around ZNF705D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF705D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF705D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF705D Gene

Proteins for ZNF705D Gene

  • Protein details for ZNF705D Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 705D
    Protein Accession:
    Secondary Accessions:
    • A8K971
    • A8MY01
    • Q2TAN0

    Protein attributes for ZNF705D Gene

    300 amino acids
    Molecular mass:
    34712 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF705D Gene

Post-translational modifications for ZNF705D Gene

No Post-translational modifications

Other Protein References for ZNF705D Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF705D Gene

Domains & Families for ZNF705D Gene

Gene Families for ZNF705D Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF705D Gene

Suggested Antigen Peptide Sequences for ZNF705D Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF705D: view

Function for ZNF705D Gene

Molecular function for ZNF705D Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF705D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF705D: view

Phenotypes for ZNF705D Gene

genes like me logo Genes that share phenotypes with ZNF705D: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF705D Gene

Localization for ZNF705D Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF705D Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF705D gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF705D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF705D: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF705D Gene

Pathways & Interactions for ZNF705D Gene

SuperPathways for ZNF705D Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF705D: view

Pathways by source for ZNF705D Gene

2 Reactome pathways for ZNF705D Gene

Interacting Proteins for ZNF705D Gene

Gene Ontology (GO) - Biological Process for ZNF705D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF705D: view

No data available for SIGNOR curated interactions for ZNF705D Gene

Drugs & Compounds for ZNF705D Gene

No Compound Related Data Available

Transcripts for ZNF705D Gene

mRNA/cDNA for ZNF705D Gene

(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF705D Gene

Zinc finger protein 705D:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF705D Gene

No ASD Table

Relevant External Links for ZNF705D Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF705D Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF705D Gene

mRNA differential expression in normal tissues according to GTEx for ZNF705D Gene

This gene is overexpressed in Testis (x42.5) and Brain - Caudate (basal ganglia) (x5.6).

NURSA nuclear receptor signaling pathways regulating expression of ZNF705D Gene:


SOURCE GeneReport for Unigene cluster for ZNF705D Gene:


Evidence on tissue expression from TISSUES for ZNF705D Gene

  • Skin(4)
genes like me logo Genes that share expression patterns with ZNF705D: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF705D Gene

Orthologs for ZNF705D Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF705D Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 95 (a)
(Canis familiaris)
Mammalia LOC482938 33
  • 74.22 (n)
-- 34
  • 56 (a)
(Bos Taurus)
Mammalia ZNF705A 33 34
  • 73.83 (n)
-- 34
  • 28 (a)
Species where no ortholog for ZNF705D was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF705D Gene

Gene Tree for ZNF705D (if available)
Gene Tree for ZNF705D (if available)

Paralogs for ZNF705D Gene

Paralogs for ZNF705D Gene

(335) SIMAP similar genes for ZNF705D Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF705D: view

Variants for ZNF705D Gene

Sequence variations from dbSNP and Humsavar for ZNF705D Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1001257641 -- 12,093,862(+) C/G genic_upstream_transcript_variant, intron_variant
rs1001287453 -- 12,094,692(+) C/A genic_upstream_transcript_variant, intron_variant
rs1002262109 -- 12,100,095(+) G/A genic_upstream_transcript_variant, intron_variant
rs1002289714 -- 12,102,761(+) G/A genic_upstream_transcript_variant, intron_variant
rs1003265028 -- 12,112,077(+) TTTTTTT/TTTTTT intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF705D Gene

Variant ID Type Subtype PubMed ID
dgv1270e199 CNV deletion 23128226
dgv154e203 CNV gain+loss 21179565
dgv244e55 CNV gain 17911159
dgv27n31 CNV gain 19718026
dgv3773n106 CNV deletion 24896259
dgv7015n100 CNV gain 25217958
dgv7016n100 CNV gain 25217958
dgv7017n100 CNV gain 25217958
dgv7018n100 CNV gain+loss 25217958
dgv7019n100 CNV gain 25217958
dgv7020n100 CNV loss 25217958
dgv7021n100 CNV loss 25217958
esv22986 CNV gain+loss 19812545
esv2660145 CNV deletion 23128226
esv2736614 CNV deletion 23290073
esv2759593 CNV gain+loss 17122850
nsv1034132 CNV gain 25217958
nsv1075529 CNV deletion 25765185
nsv1075530 CNV deletion 25765185
nsv1122187 CNV deletion 24896259
nsv1161718 OTHER complex 26073780
nsv428195 CNV gain 18775914
nsv471461 CNV gain 19718026
nsv516685 CNV gain+loss 19592680
nsv8288 CNV gain+loss 18304495
nsv951104 CNV deletion 24416366
nsv967564 CNV duplication 23825009

Variation tolerance for ZNF705D Gene

Gene Damage Index Score: 0.08; 1.90% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF705D Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF705D Gene

Disorders for ZNF705D Gene

Additional Disease Information for ZNF705D

No disorders were found for ZNF705D Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF705D Gene

Publications for ZNF705D Gene

  1. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C … Lander ES (Nature 2006) 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for ZNF705D Gene

Sources for ZNF705D Gene

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