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Aliases for ZNF705B Gene

Aliases for ZNF705B Gene

  • Zinc Finger Protein 705B 2 3 5

External Ids for ZNF705B Gene

Previous GeneCards Identifiers for ZNF705B Gene

  • GC08P007843
  • GC08U900738
  • GC08P007783

Summaries for ZNF705B Gene

GeneCards Summary for ZNF705B Gene

ZNF705B (Zinc Finger Protein 705B) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF705D.

UniProtKB/Swiss-Prot for ZNF705B Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF705B Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF705B Gene

Genomics for ZNF705B Gene

GeneHancer (GH) Regulatory Elements for ZNF705B Gene

Promoters and enhancers for ZNF705B Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08I007926 Promoter 0.5 EPDnew 550.8 +0.0 3 0.1 PIR58774 ZNF705B DEFB108A
GH08I007935 Promoter 0.5 EPDnew 550.4 +8.8 8843 0.1 ZNF705B DEFB108A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF705B on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZNF705B Gene

Genomic Locations for ZNF705B Gene
26,077 bases
Plus strand

Genomic View for ZNF705B Gene

Genes around ZNF705B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF705B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF705B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF705B Gene

Proteins for ZNF705B Gene

  • Protein details for ZNF705B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative zinc finger protein 705B
    Protein Accession:
    Secondary Accessions:
    • A8K971
    • A8MY01

    Protein attributes for ZNF705B Gene

    300 amino acids
    Molecular mass:
    34732 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF705B Gene

Post-translational modifications for ZNF705B Gene

No Post-translational modifications

Other Protein References for ZNF705B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF705B Gene

Domains & Families for ZNF705B Gene

Gene Families for ZNF705B Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF705B Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF705B: view

No data available for Suggested Antigen Peptide Sequences for ZNF705B Gene

Function for ZNF705B Gene

Molecular function for ZNF705B Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF705B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF705B: view

Phenotypes for ZNF705B Gene

GenomeRNAi human phenotypes for ZNF705B:
genes like me logo Genes that share phenotypes with ZNF705B: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF705B Gene

Localization for ZNF705B Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF705B Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF705B gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF705B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF705B: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF705B Gene

Pathways & Interactions for ZNF705B Gene

SuperPathways for ZNF705B Gene

No Data Available

Interacting Proteins for ZNF705B Gene

Gene Ontology (GO) - Biological Process for ZNF705B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF705B: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF705B Gene

Drugs & Compounds for ZNF705B Gene

No Compound Related Data Available

Transcripts for ZNF705B Gene

mRNA/cDNA for ZNF705B Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF705B Gene

Zinc finger protein 705B:
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF705B Gene

No ASD Table

Relevant External Links for ZNF705B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF705B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF705B Gene

mRNA differential expression in normal tissues according to GTEx for ZNF705B Gene

This gene is overexpressed in Testis (x53.0).

NURSA nuclear receptor signaling pathways regulating expression of ZNF705B Gene:


SOURCE GeneReport for Unigene cluster for ZNF705B Gene:

genes like me logo Genes that share expression patterns with ZNF705B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF705B Gene

Orthologs for ZNF705B Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF705B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 95 (a)
(Canis familiaris)
Mammalia LOC482938 33
  • 74.11 (n)
-- 34
  • 57 (a)
(Bos Taurus)
Mammalia ZNF705A 33 34
  • 73.71 (n)
-- 34
  • 28 (a)
Species where no ortholog for ZNF705B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF705B Gene

Gene Tree for ZNF705B (if available)
Gene Tree for ZNF705B (if available)

Paralogs for ZNF705B Gene

Paralogs for ZNF705B Gene

(234) SIMAP similar genes for ZNF705B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF705B: view

Variants for ZNF705B Gene

Sequence variations from dbSNP and Humsavar for ZNF705B Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1000081281 -- 7,936,661(+) G/A intron_variant
rs1001205100 -- 7,930,647(+) T/C intron_variant
rs1002158477 -- 7,928,000(+) G/C intron_variant
rs1002614999 -- 7,938,578(+) G/T intron_variant
rs1003931956 -- 7,939,851(+) T/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF705B Gene

Variant ID Type Subtype PubMed ID
dgv1170n67 CNV loss 20364138
dgv11911n54 CNV loss 21841781
dgv11913n54 CNV gain 21841781
dgv11914n54 CNV gain 21841781
dgv11928n54 CNV gain 21841781
dgv11930n54 CNV gain 21841781
dgv11931n54 CNV loss 21841781
dgv11932n54 CNV loss 21841781
dgv1265e199 CNV deletion 23128226
dgv13n29 CNV gain+loss 16826518
dgv2035e212 CNV gain 25503493
dgv262n111 CNV deletion 26073780
dgv3764n106 CNV deletion 24896259
dgv6882n100 CNV gain 25217958
dgv6887n100 CNV loss 25217958
dgv6890n100 CNV gain 25217958
dgv6895n100 CNV loss 25217958
dgv6896n100 CNV gain+loss 25217958
dgv6909n100 CNV gain 25217958
dgv6910n100 CNV gain+loss 25217958
dgv6911n100 CNV loss 25217958
dgv6912n100 CNV loss 25217958
dgv6915n100 CNV gain 25217958
dgv6935n100 CNV gain 25217958
dgv6936n100 CNV gain+loss 25217958
dgv6940n100 CNV loss 25217958
dgv6948n100 CNV gain+loss 25217958
dgv6949n100 CNV gain 25217958
dgv6950n100 CNV loss 25217958
dgv6955n100 CNV gain 25217958
dgv6960n100 CNV loss 25217958
dgv6961n100 CNV gain+loss 25217958
dgv6962n100 CNV gain 25217958
dgv6963n100 CNV loss 25217958
dgv6964n100 CNV gain 25217958
dgv6965n100 CNV gain+loss 25217958
dgv6966n100 CNV loss 25217958
dgv6968n100 CNV gain 25217958
dgv6969n100 CNV gain+loss 25217958
dgv6970n100 CNV gain 25217958
dgv6971n100 CNV loss 25217958
dgv6972n100 CNV loss 25217958
dgv6974n100 CNV gain+loss 25217958
dgv6975n100 CNV loss 25217958
dgv6976n100 CNV loss 25217958
dgv6977n100 CNV gain 25217958
dgv6978n100 CNV loss 25217958
dgv6979n100 CNV gain+loss 25217958
dgv6980n100 CNV gain 25217958
dgv6981n100 CNV loss 25217958
dgv6982n100 CNV loss 25217958
dgv6983n100 CNV loss 25217958
dgv6984n100 CNV gain+loss 25217958
dgv6985n100 CNV loss 25217958
dgv6986n100 CNV loss 25217958
dgv6987n100 CNV loss 25217958
dgv6988n100 CNV loss 25217958
dgv6989n100 CNV gain 25217958
esv25631 CNV gain+loss 19812545
esv2752265 CNV gain 17911159
esv2752266 CNV loss 17911159
esv2759589 CNV gain+loss 17122850
esv2761169 CNV gain+loss 21179565
esv2764098 CNV gain+loss 21179565
esv3584574 CNV gain 24956385
esv3584577 CNV gain 24956385
esv3891318 CNV gain 25118596
esv3891321 CNV gain+loss 25118596
esv3891323 CNV gain+loss 25118596
esv992071 CNV gain 20482838
nsv1015205 CNV gain+loss 25217958
nsv1017081 CNV gain 25217958
nsv1020728 CNV gain+loss 25217958
nsv1022975 CNV loss 25217958
nsv1025485 CNV gain 25217958
nsv1028034 CNV gain+loss 25217958
nsv1030619 CNV loss 25217958
nsv1030975 CNV gain+loss 25217958
nsv1031577 CNV gain 25217958
nsv1032809 CNV loss 25217958
nsv1075524 CNV deletion 25765185
nsv1122186 CNV deletion 24896259
nsv1126840 CNV deletion 24896259
nsv1141576 CNV duplication 24896259
nsv1141577 CNV duplication 24896259
nsv428194 CNV gain+loss 18775914
nsv433398 CNV gain 18776910
nsv438034 CNV loss 16468122
nsv442397 CNV gain 18776908
nsv471477 CNV gain 19718026
nsv471650 CNV gain+loss 15918152
nsv471651 CNV gain+loss 15918152
nsv508496 CNV deletion 20534489
nsv510977 OTHER complex 20534489
nsv515968 CNV gain+loss 19592680
nsv610136 CNV gain 21841781
nsv610137 CNV loss 21841781
nsv821656 CNV gain 15273396
nsv824524 CNV gain+loss 20364138
nsv8281 CNV gain+loss 18304495
nsv951093 CNV deletion 24416366
nsv967560 CNV duplication 23825009
nsv967561 CNV duplication 23825009

Variation tolerance for ZNF705B Gene

Gene Damage Index Score: 0.88; 18.29% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF705B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF705B Gene

Disorders for ZNF705B Gene

Additional Disease Information for ZNF705B

No disorders were found for ZNF705B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF705B Gene

Publications for ZNF705B Gene

  1. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C … Lander ES (Nature 2006) 3 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58

Products for ZNF705B Gene

Sources for ZNF705B Gene

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