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Aliases for ZNF700 Gene

Aliases for ZNF700 Gene

  • Zinc Finger Protein 700 2 3 4 5

External Ids for ZNF700 Gene

Previous GeneCards Identifiers for ZNF700 Gene

  • GC19P011884
  • GC19P012035
  • GC19P011610

Summaries for ZNF700 Gene

GeneCards Summary for ZNF700 Gene

ZNF700 (Zinc Finger Protein 700) is a Protein Coding gene. Among its related pathways are Herpes simplex virus 1 infection and Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF433.

UniProtKB/Swiss-Prot for ZNF700 Gene

Additional gene information for ZNF700 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF700 Gene

Genomics for ZNF700 Gene

GeneHancer (GH) Regulatory Elements for ZNF700 Gene

Promoters and enhancers for ZNF700 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J011923 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 650.6 +0.5 533 4.4 HDGF ZNF652 ZFX SP1 CTCF ZNF148 NKRF POLR2A ZNF121 CEBPG ZNF700 ENSG00000267179 ZNF627 ZNF136 ZNF44 ZNF763 ZNF20 ZNF564 ZNF442 ZNF791
GH19J012781 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 64.3 +864.2 864230 16 MTA3 ZNF652 SP1 ZFX CC2D1A ELF3 CTCF MNT SIX5 CBFA2T2 IER2 CCDC130 ZNF136 ZNF44 ZNF791 ZNF564 TRMT1 WDR83OS ZNF442 MRI1
GH19J012918 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 44.5 +994.8 994802 2.2 ZFX SP1 NKRF MLLT1 ZNF121 POLR2A ZNF384 ZNF687 ZSCAN21 ZBTB7A MIR5695 SYCE2 CCDC130 ZNF136 TRMT1 ZNF44 ZNF20 ZNF763 ZNF564 ZNF700
GH19J012609 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE 37.5 +687.1 687107 5.2 SP1 ZFX ELF3 MNT SIX5 NKRF POLR2A MLLT1 CEBPG RERE ZNF490 ZNF791 PIR37932 ZNF136 ZNF44 ZNF442 ZNF844 ZNF20 ZNF564 ZNF700
GH19J012774 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 28.6 +852.3 852338 6.2 SP1 ZFX ELF3 CTCF ZKSCAN8 MNT SIX5 CBFA2T2 ZNF148 NKRF GC19P012779 HOOK2 CCDC130 WDR83OS ZNF44 ZNF564 ZNF700 ZNF136 ZNF799 TRIR
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF700 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZNF700 Gene

Genomic Locations for ZNF700 Gene
chr19:11,925,068-11,950,773
(GRCh38/hg38)
Size:
25,706 bases
Orientation:
Plus strand
chr19:12,035,883-12,061,588
(GRCh37/hg19)
Size:
25,706 bases
Orientation:
Plus strand

Genomic View for ZNF700 Gene

Genes around ZNF700 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF700 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF700 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF700 Gene

Proteins for ZNF700 Gene

  • Protein details for ZNF700 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H0M5-ZN700_HUMAN
    Recommended name:
    Zinc finger protein 700
    Protein Accession:
    Q9H0M5
    Secondary Accessions:
    • B9EGU4

    Protein attributes for ZNF700 Gene

    Size:
    742 amino acids
    Molecular mass:
    86232 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF700 Gene

Post-translational modifications for ZNF700 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF700 Gene

No data available for DME Specific Peptides for ZNF700 Gene

Domains & Families for ZNF700 Gene

Gene Families for ZNF700 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF700 Gene

Suggested Antigen Peptide Sequences for ZNF700 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 700 (ZN700_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9H0M5

UniProtKB/Swiss-Prot:

ZN700_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF700: view

Function for ZNF700 Gene

Molecular function for ZNF700 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF700 Gene

Gene Ontology (GO) - Molecular Function for ZNF700 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific ISA --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF700: view
genes like me logo Genes that share phenotypes with ZNF700: view

Animal Model Products

CRISPR Products

miRNA for ZNF700 Gene

miRTarBase miRNAs that target ZNF700

Clone Products

  • Applied Biological Materials (abm): Clones for ZNF700 - Now 50% OFF >
  • * ZNF700 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * ZNF700 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF700 Gene

Localization for ZNF700 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF700 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF700 gene
Compartment Confidence
nucleus 4

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF700 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF700: view

Pathways & Interactions for ZNF700 Gene

genes like me logo Genes that share pathways with ZNF700: view

Pathways by source for ZNF700 Gene

2 Reactome pathways for ZNF700 Gene
1 KEGG pathway for ZNF700 Gene

Gene Ontology (GO) - Biological Process for ZNF700 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006357 regulation of transcription by RNA polymerase II IEA --
genes like me logo Genes that share ontologies with ZNF700: view

No data available for SIGNOR curated interactions for ZNF700 Gene

Drugs & Compounds for ZNF700 Gene

No Compound Related Data Available

Transcripts for ZNF700 Gene

mRNA/cDNA for ZNF700 Gene

(3) REFSEQ mRNAs :
(8) Additional mRNA sequences :
(22) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Unigene Clusters for ZNF700 Gene

Zinc finger protein 700:
Representative Sequences:

CRISPR Products

Clone Products

  • Applied Biological Materials (abm): Clones for ZNF700 - Now 50% OFF >
  • * ZNF700 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * ZNF700 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF700 Gene

No ASD Table

Relevant External Links for ZNF700 Gene

GeneLoc Exon Structure for
ZNF700
ECgene alternative splicing isoforms for
ZNF700

Expression for ZNF700 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF700 Gene

Protein differential expression in normal tissues from HIPED for ZNF700 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF700 Gene



Protein tissue co-expression partners for ZNF700 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF700 Gene:

ZNF700

SOURCE GeneReport for Unigene cluster for ZNF700 Gene:

Hs.528486

Evidence on tissue expression from TISSUES for ZNF700 Gene

  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZNF700: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF700 Gene

Orthologs for ZNF700 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF700 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF700 35
  • 99 (a)
OneToOne
LOC100614631 34
  • 98.37 (n)
rat
(Rattus norvegicus)
Mammalia LOC102550944 34
  • 67.92 (n)
mouse
(Mus musculus)
Mammalia Gm19428 34
  • 67.87 (n)
Gm7762 17
cow
(Bos Taurus)
Mammalia -- 35
  • 50 (a)
ManyToMany
Species where no ortholog for ZNF700 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF700 Gene

ENSEMBL:
Gene Tree for ZNF700 (if available)
TreeFam:
Gene Tree for ZNF700 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF700: view image

Paralogs for ZNF700 Gene

(536) SIMAP similar genes for ZNF700 Gene using alignment to 2 proteins:

  • ZN700_HUMAN
  • K7EQV7_HUMAN

Pseudogenes.org Pseudogenes for ZNF700 Gene

genes like me logo Genes that share paralogs with ZNF700: view

Variants for ZNF700 Gene

Sequence variations from dbSNP and Humsavar for ZNF700 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000057418 -- 11,945,987(+) G/C intron_variant
rs1000118339 -- 11,941,121(+) G/A intron_variant
rs1000430019 -- 11,945,837(+) G/C intron_variant
rs1000536597 -- 11,923,777(+) G/A upstream_transcript_variant
rs1000541068 -- 11,941,326(+) C/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF700 Gene

Variant ID Type Subtype PubMed ID
dgv3428n100 CNV gain 25217958
dgv3429n100 CNV loss 25217958
dgv623e199 CNV deletion 23128226
dgv6268n54 CNV loss 21841781
dgv6269n54 CNV loss 21841781
esv23756 CNV loss 19812545
esv2660126 CNV deletion 23128226
esv2662395 CNV deletion 23128226
esv2718185 CNV deletion 23290073
esv2718187 CNV deletion 23290073
esv2718188 CNV deletion 23290073
esv2718189 CNV deletion 23290073
esv3096012 CNV deletion 24192839
esv3556034 CNV deletion 23714750
esv3556035 CNV deletion 23714750
esv3583245 CNV loss 25503493
esv3643677 CNV gain 21293372
esv3643684 CNV loss 21293372
esv3643685 CNV gain 21293372
esv3643686 CNV loss 21293372
esv3643687 CNV gain 21293372
nsv1076465 CNV duplication 25765185
nsv2417 CNV deletion 18451855
nsv482215 CNV gain 20164927
nsv507887 OTHER sequence alteration 20534489
nsv525966 CNV gain 19592680
nsv578619 CNV loss 21841781
nsv960791 CNV duplication 23825009

Variation tolerance for ZNF700 Gene

Residual Variation Intolerance Score: 29.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.79; 66.78% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF700 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF700

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF700 Gene

Disorders for ZNF700 Gene

Additional Disease Information for ZNF700

No disorders were found for ZNF700 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF700 Gene

Publications for ZNF700 Gene

  1. Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S … Poustka A (Genome research 2001) 3 4 58
  2. Diagnostic potential of zinc finger protein-specific autoantibodies and associated linear B-cell epitopes in colorectal cancer. (PMID: 25875936) O'Reilly JA … Kijanka GS (PloS one 2015) 3 58
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for ZNF700 Gene

Sources for ZNF700 Gene

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