Aliases for ZNF672 Gene

Aliases for ZNF672 Gene

  • Zinc Finger Protein 672 2 3 4 5
  • Hypothetical Protein FLJ22301 2
  • FLJ22301 2
  • ZNF672 5

External Ids for ZNF672 Gene

Previous GeneCards Identifiers for ZNF672 Gene

  • GC01P245343
  • GC01P247099
  • GC01P249132
  • GC01P219373

Summaries for ZNF672 Gene

GeneCards Summary for ZNF672 Gene

ZNF672 (Zinc Finger Protein 672) is a Protein Coding gene. Diseases associated with ZNF672 include Wolf-Hirschhorn Syndrome. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF45.

UniProtKB/Swiss-Prot Summary for ZNF672 Gene

Additional gene information for ZNF672 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF672 Gene

Genomics for ZNF672 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZNF672 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J248837 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 600.7 +0.3 291 3.4 SP1 HNRNPL CREB1 REST IKZF1 RFX5 POLR2A ZNF692 FOS JUND ZNF672 lnc-ZNF672-2 PGBD2 piR-59528 ZNF692
GH01J248924 Enhancer 1 Ensembl ENCODE 11.5 +88.9 88891 6.2 CTCF IKZF1 JUND PKNOX1 REST RAD21 ZNF24 IKZF2 TRIM22 DPF2 piR-31717-002 ZNF672 ZNF692 ENSG00000227237 PGBD2 SH3BP5L piR-51583
GH01J248886 Enhancer 0.6 Ensembl dbSUPER 11.6 +48.1 48091 1.4 IKZF1 NFIC ZNF592 MEIS2 SH3BP5L RNU6-1205P ZNF672 ZNF692 ENSG00000227237 piR-41960 MN296948 PGBD2
GH01J248816 Enhancer 0.5 ENCODE 11.9 -21.0 -20993 0.2 SPI1 CEBPB POLR2A MYC MAX lnc-ZNF692-1 ZNF672 ENSG00000227237 ZNF692 PGBD2 SH3BP5L LYPD8
GH01J248881 Enhancer 0.5 Ensembl 11.8 +43.6 43591 0.8 PRDM10 MNT MEIS2 ZBTB40 ATF7 ZNF692 ENSG00000227237 ZNF672 RNU6-1205P MN296948 PGBD2 piR-41960
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF672 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF672

Top Transcription factor binding sites by QIAGEN in the ZNF672 gene promoter:
  • AML1a
  • C/EBPalpha
  • deltaCREB
  • Evi-1
  • HEN1
  • Olf-1
  • RSRFC4
  • Sox5
  • STAT3

Genomic Locations for ZNF672 Gene

Genomic Locations for ZNF672 Gene
11,308 bases
Plus strand
11,308 bases
Plus strand

Genomic View for ZNF672 Gene

Genes around ZNF672 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF672 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF672 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF672 Gene

Proteins for ZNF672 Gene

  • Protein details for ZNF672 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 672
    Protein Accession:
    Secondary Accessions:
    • Q96H65
    • Q96IM3
    • Q9H6G5

    Protein attributes for ZNF672 Gene

    452 amino acids
    Molecular mass:
    50224 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH08872.1; Type=Miscellaneous discrepancy; Note=Non-canonical splice intron-exon junction.; Evidence={ECO:0000305};

neXtProt entry for ZNF672 Gene

Post-translational modifications for ZNF672 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF672 Gene

No data available for DME Specific Peptides for ZNF672 Gene

Domains & Families for ZNF672 Gene

Gene Families for ZNF672 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF672 Gene


Suggested Antigen Peptide Sequences for ZNF672 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 672 (ZN672_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF672: view

Function for ZNF672 Gene

Molecular function for ZNF672 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF672 Gene

Gene Ontology (GO) - Molecular Function for ZNF672 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF672: view
genes like me logo Genes that share phenotypes with ZNF672: view

Animal Model Products

CRISPR Products

miRNA for ZNF672 Gene

miRTarBase miRNAs that target ZNF672

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF672

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF672 Gene

Localization for ZNF672 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF672 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF672 gene
Compartment Confidence
nucleus 5
lysosome 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF672 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with ZNF672: view

Pathways & Interactions for ZNF672 Gene

PathCards logo

SuperPathways for ZNF672 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF672 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZNF672 Gene

Drugs & Compounds for ZNF672 Gene

No Compound Related Data Available

Transcripts for ZNF672 Gene

mRNA/cDNA for ZNF672 Gene

13 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF672

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF672 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c
SP1: - - - - - - - - -
SP2: - - - - - - -
SP3: - - - - - - - -
SP4: - - - -
SP5: - -
SP6: - - - - - -
SP7: - - - -
SP8: -

Relevant External Links for ZNF672 Gene

GeneLoc Exon Structure for

Expression for ZNF672 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF672 Gene

Protein differential expression in normal tissues from HIPED for ZNF672 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (66.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF672 Gene

Protein tissue co-expression partners for ZNF672 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF672

SOURCE GeneReport for Unigene cluster for ZNF672 Gene:


Evidence on tissue expression from TISSUES for ZNF672 Gene

  • Nervous system(4.8)
genes like me logo Genes that share expression patterns with ZNF672: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF672 Gene

Orthologs for ZNF672 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF672 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF672 31
  • 99 (a)
(Bos Taurus)
Mammalia ZNF672 30 31
  • 80.93 (n)
(Canis familiaris)
Mammalia ZNF672 30 31
  • 79.57 (n)
(Mus musculus)
Mammalia Zfp672 30 17 31
  • 75.09 (n)
(Rattus norvegicus)
Mammalia Zfp672 30
  • 74.35 (n)
(Monodelphis domestica)
Mammalia ZNF672 31
  • 64 (a)
Species where no ortholog for ZNF672 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for ZNF672 Gene

Gene Tree for ZNF672 (if available)
Gene Tree for ZNF672 (if available)
Evolutionary constrained regions (ECRs) for ZNF672: view image

Paralogs for ZNF672 Gene

Paralogs for ZNF672 Gene

(484) SIMAP similar genes for ZNF672 Gene using alignment to 3 proteins:

  • ZN672_HUMAN
  • D6RD56_HUMAN
  • D6RH11_HUMAN
genes like me logo Genes that share paralogs with ZNF672: view

Variants for ZNF672 Gene

Additional dbSNP identifiers (rs#s) for ZNF672 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF672 Gene

Variant ID Type Subtype PubMed ID
dgv631n100 CNV gain 25217958
dgv644n100 CNV gain 25217958
esv2750832 CNV gain 17911159
esv2750835 CNV gain 17911159
esv3589576 CNV gain 21293372
esv3589577 CNV gain 21293372
nsv5398 CNV insertion 18451855
nsv549745 CNV loss 21841781
nsv999043 CNV gain 25217958

Variation tolerance for ZNF672 Gene

Gene Damage Index Score: 0.73; 15.40% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF672 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF672 Gene

Disorders for ZNF672 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZNF672 Gene - From: DISEASES

Disorder Aliases PubMed IDs
wolf-hirschhorn syndrome
  • whs
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for ZNF672

genes like me logo Genes that share disorders with ZNF672: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF672 Gene

Publications for ZNF672 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3
  4. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3

Products for ZNF672 Gene

  • Signalway Proteins for ZNF672

Sources for ZNF672 Gene