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Aliases for ZNF672 Gene

Aliases for ZNF672 Gene

  • Zinc Finger Protein 672 2 3 5
  • Hypothetical Protein FLJ22301 2

External Ids for ZNF672 Gene

Previous GeneCards Identifiers for ZNF672 Gene

  • GC01P245343
  • GC01P247099
  • GC01P249132
  • GC01P219373

Summaries for ZNF672 Gene

GeneCards Summary for ZNF672 Gene

ZNF672 (Zinc Finger Protein 672) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding.

UniProtKB/Swiss-Prot for ZNF672 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF672 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF672 Gene

Genomics for ZNF672 Gene

GeneHancer (GH) Regulatory Elements for ZNF672 Gene

Promoters and enhancers for ZNF672 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I248837 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 +0.3 330 2.8 HDGF PKNOX1 CLOCK SMAD1 ARID4B SIN3A YY1 SLC30A9 POLR2B E2F8 ZNF672 PGBD2 PIR53527
GH01I248924 Enhancer 1.1 Ensembl ENCODE 11.5 +87.8 87767 2.5 HDAC1 HDGF PKNOX1 ATF1 TAF9B ARNT BATF RAD21 RFX5 TCF12 ZNF672 ENSG00000227237 ZNF692 PGBD2 SH3BP5L PIR45582 PIR40629 GC01P248921
GH01I248816 Enhancer 0.7 Ensembl ENCODE 11.9 -21.2 -21177 1.2 POLR2A CEBPB MAX MYC SPI1 ZNF672 ZNF692 ENSG00000227237 PGBD2 SH3BP5L MIR3124 GC01P248810
GH01I248886 Enhancer 0.7 Ensembl dbSUPER 11.6 +48.5 48523 0.2 MEIS2 NFIC IKZF1 ZNF592 RNU6-1205P ZNF672 ENSG00000227237 ZNF692 SH3BP5L PIR34959 TRE-CTC2-1 PGBD2
GH01I248862 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 1.6 +25.1 25123 1.4 ATF1 RB1 ARID4B SIN3A DMAP1 ZNF48 ZSCAN9 RARA YY1 ZNF335 SH3BP5L ZNF692 OR14I1 ZNF672 ENSG00000227237 PGBD2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF672 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF672 gene promoter:

Genomic Locations for ZNF672 Gene

Genomic Locations for ZNF672 Gene
11,340 bases
Plus strand

Genomic View for ZNF672 Gene

Genes around ZNF672 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF672 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF672 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF672 Gene

Proteins for ZNF672 Gene

  • Protein details for ZNF672 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 672
    Protein Accession:
    Secondary Accessions:
    • Q96H65
    • Q96IM3
    • Q9H6G5

    Protein attributes for ZNF672 Gene

    452 amino acids
    Molecular mass:
    50224 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF672 Gene


neXtProt entry for ZNF672 Gene

Post-translational modifications for ZNF672 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF672 Gene

No data available for DME Specific Peptides for ZNF672 Gene

Domains & Families for ZNF672 Gene

Gene Families for ZNF672 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF672 Gene

Suggested Antigen Peptide Sequences for ZNF672 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF672: view

Function for ZNF672 Gene

Molecular function for ZNF672 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF672 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF672: view
genes like me logo Genes that share phenotypes with ZNF672: view

miRNA for ZNF672 Gene

miRTarBase miRNAs that target ZNF672

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF672 Gene

Localization for ZNF672 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF672 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF672 gene
Compartment Confidence
nucleus 5

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF672 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with ZNF672: view

Pathways & Interactions for ZNF672 Gene

SuperPathways for ZNF672 Gene

No Data Available

Interacting Proteins for ZNF672 Gene

Gene Ontology (GO) - Biological Process for ZNF672 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF672: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF672 Gene

Drugs & Compounds for ZNF672 Gene

No Compound Related Data Available

Transcripts for ZNF672 Gene

Unigene Clusters for ZNF672 Gene

Zinc finger protein 672:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF672 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c
SP1: - - - - - - - - -
SP2: - - - - - - -
SP3: - - - - - - - -
SP4: - - - -
SP5: - -
SP6: - - - - - -
SP7: - - - -
SP8: -

Relevant External Links for ZNF672 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF672 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF672 Gene

Protein differential expression in normal tissues from HIPED for ZNF672 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (66.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF672 Gene

Protein tissue co-expression partners for ZNF672 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF672 Gene:


SOURCE GeneReport for Unigene cluster for ZNF672 Gene:


Evidence on tissue expression from TISSUES for ZNF672 Gene

  • Nervous system(4.8)
genes like me logo Genes that share expression patterns with ZNF672: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF672 Gene

Orthologs for ZNF672 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF672 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF672 34
  • 99 (a)
(Bos Taurus)
Mammalia ZNF672 33 34
  • 80.93 (n)
(Canis familiaris)
Mammalia ZNF672 33 34
  • 79.57 (n)
(Mus musculus)
Mammalia Zfp672 33 16 34
  • 75.09 (n)
(Rattus norvegicus)
Mammalia Zfp672 33
  • 74.35 (n)
(Monodelphis domestica)
Mammalia ZNF672 34
  • 64 (a)
Species where no ortholog for ZNF672 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF672 Gene

Gene Tree for ZNF672 (if available)
Gene Tree for ZNF672 (if available)

Paralogs for ZNF672 Gene

(484) SIMAP similar genes for ZNF672 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF672: view

No data available for Paralogs for ZNF672 Gene

Variants for ZNF672 Gene

Sequence variations from dbSNP and Humsavar for ZNF672 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000038682 -- 248,841,069(+) T/C intron_variant
rs1000358394 -- 248,849,310(+) C/T 3_prime_UTR_variant
rs1000967767 -- 248,844,109(+) A/G intron_variant
rs1001336152 -- 248,840,981(+) T/C intron_variant
rs1001429295 -- 248,841,762(+) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF672 Gene

Variant ID Type Subtype PubMed ID
dgv631n100 CNV gain 25217958
dgv644n100 CNV gain 25217958
esv2750832 CNV gain 17911159
esv2750835 CNV gain 17911159
esv3589576 CNV gain 21293372
esv3589577 CNV gain 21293372
nsv5398 CNV insertion 18451855
nsv549745 CNV loss 21841781
nsv999043 CNV gain 25217958

Variation tolerance for ZNF672 Gene

Gene Damage Index Score: 0.73; 15.40% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF672 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF672 Gene

Disorders for ZNF672 Gene

Additional Disease Information for ZNF672

No disorders were found for ZNF672 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF672 Gene

Publications for ZNF672 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  5. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A … Hentze MW (Cell 2012) 3 58

Products for ZNF672 Gene

Sources for ZNF672 Gene

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