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Aliases for ZNF671 Gene

Aliases for ZNF671 Gene

  • Zinc Finger Protein 671 2 3 5
  • Hypothetical Protein FLJ23506 2

External Ids for ZNF671 Gene

Previous GeneCards Identifiers for ZNF671 Gene

  • GC19M062923
  • GC19M058231
  • GC19M054543

Summaries for ZNF671 Gene

GeneCards Summary for ZNF671 Gene

ZNF671 (Zinc Finger Protein 671) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and transcription cofactor activity. An important paralog of this gene is ZNF304.

UniProtKB/Swiss-Prot for ZNF671 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF671 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF671 Gene

Genomics for ZNF671 Gene

GeneHancer (GH) Regulatory Elements for ZNF671 Gene

Promoters and enhancers for ZNF671 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I057726 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE 558.4 +0.2 215 1.6 PKNOX1 ATF1 RB1 NFRKB SIN3A ZBTB40 YY1 POLR2B CBX5 EGR1 ZNF671 ZNF586 PIR59096 ENSG00000269026
GH19I057632 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 10.8 +94.2 94211 1.8 PKNOX1 ARID4B SIN3A DMAP1 YY1 SLC30A9 POLR2B ZNF207 ZNF143 FOS ZNF211 GC19M057341 ZNF264 TRIM28 ZNF548 ZNF805 ZNF550 ZNF134 ZNF543 ZNF417
GH19I057769 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 11 -42.6 -42597 2.4 PKNOX1 ATF1 SIN3A YY1 ETS1 POLR2B ZNF766 CBX5 ELK1 ZNF207 ZNF586 ZNF814 ZNF776 ZNF671 ZNF417 ZNF154 ZNF256 RPL19P19 ZSCAN4 ZNF419
GH19I057663 Promoter/Enhancer 1.6 FANTOM5 Ensembl ENCODE 12.6 +63.0 63018 1.6 ARID4B ZNF76 ZNF2 ZNF48 RARA ZNF335 GLIS2 ZNF366 ZNF143 THAP11 TPRG1LP1 ZNF671 ZNF256 ZNF749 ZNF419 ZNF211 RPL19P19 VN1R1 ENSG00000269867 ZNF418
GH19I057934 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE 9.8 -207.6 -207585 1.6 MXI1 PKNOX1 SUZ12 NFIB MAX SIN3A ZBTB40 YY1 ETS1 E2F1 ZNF418 LOC100128398 C19orf18 ZNF587 ZNF671 VN1R1 PIR52698
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF671 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF671 gene promoter:

Genomic Locations for ZNF671 Gene

Genomic Locations for ZNF671 Gene
chr19:57,719,747-57,727,627
(GRCh38/hg38)
Size:
7,881 bases
Orientation:
Minus strand
chr19:58,231,119-58,238,995
(GRCh37/hg19)

Genomic View for ZNF671 Gene

Genes around ZNF671 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF671 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF671 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF671 Gene

Proteins for ZNF671 Gene

  • Protein details for ZNF671 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TAW3-ZN671_HUMAN
    Recommended name:
    Zinc finger protein 671
    Protein Accession:
    Q8TAW3
    Secondary Accessions:
    • A6NF07
    • Q9H5E9

    Protein attributes for ZNF671 Gene

    Size:
    534 amino acids
    Molecular mass:
    60972 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH25728.1; Type=Frameshift; Positions=534; Evidence={ECO:0000305};

neXtProt entry for ZNF671 Gene

Post-translational modifications for ZNF671 Gene

  • Ubiquitination at isoforms=381
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF671 Gene

No data available for DME Specific Peptides for ZNF671 Gene

Domains & Families for ZNF671 Gene

Gene Families for ZNF671 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF671 Gene

Suggested Antigen Peptide Sequences for ZNF671 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8TAW3

UniProtKB/Swiss-Prot:

ZN671_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF671: view

Function for ZNF671 Gene

Molecular function for ZNF671 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF671 Gene

Gene Ontology (GO) - Molecular Function for ZNF671 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF671: view
genes like me logo Genes that share phenotypes with ZNF671: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF671 Gene

Localization for ZNF671 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF671 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF671 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF671 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF671: view

Pathways & Interactions for ZNF671 Gene

SuperPathways for ZNF671 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF671: view

Pathways by source for ZNF671 Gene

2 Reactome pathways for ZNF671 Gene

Gene Ontology (GO) - Biological Process for ZNF671 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF671: view

No data available for SIGNOR curated interactions for ZNF671 Gene

Drugs & Compounds for ZNF671 Gene

No Compound Related Data Available

Transcripts for ZNF671 Gene

Unigene Clusters for ZNF671 Gene

Zinc finger protein 671:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF671 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b
SP1: - -
SP2: - - -
SP3: - - - - -
SP4: - - - -
SP5: - -
SP6: -

Relevant External Links for ZNF671 Gene

GeneLoc Exon Structure for
ZNF671
ECgene alternative splicing isoforms for
ZNF671

Expression for ZNF671 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF671 Gene

Protein differential expression in normal tissues from HIPED for ZNF671 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF671 Gene



Protein tissue co-expression partners for ZNF671 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF671 Gene:

ZNF671

SOURCE GeneReport for Unigene cluster for ZNF671 Gene:

Hs.180402

Evidence on tissue expression from TISSUES for ZNF671 Gene

  • Lung(4.2)
  • Nervous system(3.4)
genes like me logo Genes that share expression patterns with ZNF671: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF671 Gene

Orthologs for ZNF671 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF671 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF671 33 34
  • 99.5 (n)
dog
(Canis familiaris)
Mammalia ZNF671 33
  • 79.72 (n)
Species where no ortholog for ZNF671 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF671 Gene

ENSEMBL:
Gene Tree for ZNF671 (if available)
TreeFam:
Gene Tree for ZNF671 (if available)

Paralogs for ZNF671 Gene

(516) SIMAP similar genes for ZNF671 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF671: view

Variants for ZNF671 Gene

Sequence variations from dbSNP and Humsavar for ZNF671 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000261499 -- 57,725,576(-) C/T intron_variant
rs1000287748 -- 57,723,726(-) C/A intron_variant
rs1000663031 -- 57,720,411(-) C/G/T 3_prime_UTR_variant
rs1000798392 -- 57,720,122(-) A/G 3_prime_UTR_variant
rs1001343179 -- 57,724,824(-) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF671 Gene

Variant ID Type Subtype PubMed ID
nsv1066059 CNV gain 25217958

Variation tolerance for ZNF671 Gene

Residual Variation Intolerance Score: 11% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.05; 68.74% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF671 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF671

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF671 Gene

Disorders for ZNF671 Gene

Additional Disease Information for ZNF671

No disorders were found for ZNF671 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF671 Gene

Publications for ZNF671 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  4. Methylomics analysis identifies ZNF671 as an epigenetically repressed novel tumor suppressor and a potential non-invasive biomarker for the detection of urothelial carcinoma. (PMID: 26320192) Yeh CM … Chan MW (Oncotarget 2015) 3 58
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58

Products for ZNF671 Gene

Sources for ZNF671 Gene

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