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Aliases for ZNF670 Gene

Aliases for ZNF670 Gene

  • Zinc Finger Protein 670 2 3 3 5

External Ids for ZNF670 Gene

Previous GeneCards Identifiers for ZNF670 Gene

  • GC01M243527
  • GC01M245266
  • GC01M247200
  • GC01M217593
  • GC01M247111
  • GC01M247114

Summaries for ZNF670 Gene

GeneCards Summary for ZNF670 Gene

ZNF670 (Zinc Finger Protein 670) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF564.

UniProtKB/Swiss-Prot for ZNF670 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF670 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF670 Gene

Genomics for ZNF670 Gene

GeneHancer (GH) Regulatory Elements for ZNF670 Gene

Promoters and enhancers for ZNF670 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J247077 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 650.7 +0.1 84 3 PKNOX1 FOXA2 MLX ARID4B SIN3A DMAP1 ZBTB7B IRF4 YY1 POLR2B ZNF670-ZNF695 ZNF670 ZNF669 AHCTF1 ENSG00000227671 ZNF124 ZNF496 ZNF695 LOC100420880
GH01J247151 Enhancer 0.3 FANTOM5 3.7 -73.1 -73129 0.3 ZNF124 ZNF670 ZNF669 ZNF695 OR2G3 OR2G2 ZNF496 FGFR3P6
GH01J247132 Enhancer 0.3 FANTOM5 2.5 -53.9 -53930 0.4 ZNF124 ZNF670 ZNF695 ZNF669 FGFR3P6
GH01J247055 Enhancer 0.8 ENCODE 0.3 +23.4 23374 0.9 ELF3 MLX RARA TCF12 ATF7 CREM ZNF680 CEBPB NFYC ZEB2 ZNF670-ZNF695 ZNF496 LOC100420880 ZNF670
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF670 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF670 gene promoter:
  • ITF-2
  • Tal-1beta
  • RFX1
  • Pax-5
  • E47
  • ZIC2
  • Zic1
  • AREB6

Genomic Locations for ZNF670 Gene

Genomic Locations for ZNF670 Gene
44,176 bases
Minus strand
133,267 bases
Minus strand

Genomic View for ZNF670 Gene

Genes around ZNF670 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF670 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF670 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF670 Gene

Proteins for ZNF670 Gene

  • Protein details for ZNF670 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 670
    Protein Accession:

    Protein attributes for ZNF670 Gene

    389 amino acids
    Molecular mass:
    44603 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF670 Gene

Post-translational modifications for ZNF670 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF670 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF670 Gene

Domains & Families for ZNF670 Gene

Gene Families for ZNF670 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF670 Gene

Suggested Antigen Peptide Sequences for ZNF670 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF670: view

Function for ZNF670 Gene

Molecular function for ZNF670 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF670 Gene

Gene Ontology (GO) - Molecular Function for ZNF670 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISA --
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0005515 protein binding IPI 19060904
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF670: view
genes like me logo Genes that share phenotypes with ZNF670: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF670 Gene

Localization for ZNF670 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF670 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF670 gene
Compartment Confidence
nucleus 5
cytosol 3
mitochondrion 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF670 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF670: view

Pathways & Interactions for ZNF670 Gene

SuperPathways for ZNF670 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF670: view

Pathways by source for ZNF670 Gene

2 Reactome pathways for ZNF670 Gene

Gene Ontology (GO) - Biological Process for ZNF670 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
GO:0006357 regulation of transcription by RNA polymerase II IEA --
genes like me logo Genes that share ontologies with ZNF670: view

No data available for SIGNOR curated interactions for ZNF670 Gene

Drugs & Compounds for ZNF670 Gene

No Compound Related Data Available

Transcripts for ZNF670 Gene

mRNA/cDNA for ZNF670 Gene

(2) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(40) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF670 Gene

Zinc finger protein 670:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF670 Gene

No ASD Table

Relevant External Links for ZNF670 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF670 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF670 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF670 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF670 Gene:


SOURCE GeneReport for Unigene cluster for ZNF670 Gene:


Evidence on tissue expression from TISSUES for ZNF670 Gene

  • Gall bladder(4.1)
  • Nervous system(3.7)
genes like me logo Genes that share expression patterns with ZNF670: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF670 Gene

Orthologs for ZNF670 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ZNF670 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF670 33
  • 99.83 (n)
Species where no ortholog for ZNF670 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF670 Gene

Gene Tree for ZNF670 (if available)
Gene Tree for ZNF670 (if available)
Evolutionary constrained regions (ECRs) for ZNF670: view image

Paralogs for ZNF670 Gene

(503) SIMAP similar genes for ZNF670 Gene using alignment to 3 proteins:

  • ZN670_HUMAN
  • F2Z2N8_HUMAN
genes like me logo Genes that share paralogs with ZNF670: view

Variants for ZNF670 Gene

Sequence variations from dbSNP and Humsavar for ZNF670 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000024522 -- 247,036,897(-) C/A 3_prime_UTR_variant
rs1000025141 -- 247,073,649(-) A/T intron_variant
rs1000083209 -- 247,041,219(-) G/T intron_variant
rs1000085854 -- 247,078,928(-) G/A upstream_transcript_variant
rs1000220611 -- 247,047,573(-) G/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF670 Gene

Variant ID Type Subtype PubMed ID
esv2672680 CNV deletion 23128226
esv29446 CNV loss 19812545
esv33129 CNV gain+loss 17666407
esv3589499 CNV loss 21293372
esv3589503 CNV loss 21293372
esv3589504 CNV loss 21293372
esv3589505 CNV loss 21293372
nsv1014012 CNV loss 25217958
nsv549546 CNV loss 21841781
nsv549547 CNV loss 21841781
nsv999879 CNV gain 25217958

Variation tolerance for ZNF670 Gene

Residual Variation Intolerance Score: 26.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.78; 16.45% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF670 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF670 Gene

Disorders for ZNF670 Gene

Additional Disease Information for ZNF670

No disorders were found for ZNF670 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF670 Gene

Publications for ZNF670 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 58
  2. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PMID: 15592455) Rush J … Comb MJ (Nature biotechnology 2005) 3 4 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58

Products for ZNF670 Gene

Sources for ZNF670 Gene

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