External Ids for ZNF658 Gene
Previous GeneCards Identifiers for ZNF658 Gene
GeneCards Summary for ZNF658 Gene
ZNF658 (Zinc Finger Protein 658) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA binding transcription factor activity. An important paralog of this gene is ZNF850.
UniProtKB/Swiss-Prot for ZNF658 Gene
Mediates transcriptional repression in response to zinc. Represses several genes, including SLC30A5, SLC30A10 and CBWD1, by binding to the zinc transcriptional regulatory element (ZTRE) (5-C[AC]C[TAG]CC[TC]-N(0-50)-[GA]G[ATC]G[TG]G-3) found in the promoter region. May play a role in the control of ribosome biogenesis, regulating predominantly rRNA levels, as well as those of several ribosomal proteins, thus coordinating this highly zinc-demanding process with the available zinc supply.