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Aliases for ZNF625-ZNF20 Gene

Subcategory (RNA class) for ZNF625-ZNF20 Gene

ncRNA

Quality Score for this RNA gene is

13

Aliases for ZNF625-ZNF20 Gene

  • ZNF625-ZNF20 Readthrough (NMD Candidate) 2 3 5 13
  • Zinc Finger Protein 625 13
  • ZNF625 13

External Ids for ZNF625-ZNF20 Gene

Previous GeneCards Identifiers for ZNF625-ZNF20 Gene

  • GC19U901507
  • GC19M012246

Summaries for ZNF625-ZNF20 Gene

Entrez Gene Summary for ZNF625-ZNF20 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring zinc finger protein 625 (ZNF625) and zinc finger protein 20 (ZNF20) genes on chromosome 19. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2011]

GeneCards Summary for ZNF625-ZNF20 Gene

ZNF625-ZNF20 (ZNF625-ZNF20 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF878.

Additional gene information for ZNF625-ZNF20 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF625-ZNF20 Gene

Genomics for ZNF625-ZNF20 Gene

GeneHancer (GH) Regulatory Elements for ZNF625-ZNF20 Gene

Promoters and enhancers for ZNF625-ZNF20 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J012155 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 600.7 +1.1 1126 3.6 SP1 ELF3 POLR2A ZSCAN21 YY1 SP7 MZF1 ZNF560 ZNF704 KAT8 ZNF625 ZNF625-ZNF20 ZNF627 ZNF20 ZNF136 TRMT1 ZNF44 ZNF442 ZNF844 FBXW9
GH19J011923 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 11.4 +231.1 231130 4.4 HDGF ZNF652 ZFX SP1 CTCF ZNF148 NKRF POLR2A ZNF121 CEBPG ZNF700 ENSG00000267179 ZNF627 ZNF136 ZNF44 ZNF763 ZNF20 ZNF564 ZNF442 ZNF791
GH19J012050 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 11.1 +104.8 104823 3.4 SP1 ELF3 NKRF POLR2A AHR SP7 HNF1A PPARG SP5 MLLT1 ENSG00000257355 ZNF878 ZNF433 ZNF433-AS1 ZNF491 ZNF441 ZNF625 RNA5SP464 ZNF625-ZNF20 RPS6P25
GH19J011797 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 11.1 +358.0 358030 2.6 SP1 ELF3 CTCF CBFA2T2 NKRF CEBPG AHR PPARG SP5 RAD21 ZNF491 ENSG00000267646 GC19P011801 PIR49375 ZNF440 ZNF441 ZNF625-ZNF20 ZNF439 ZNF433-AS1 RNA5SP464
GH19J011813 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 10.3 +341.8 341830 3.4 SP1 ZFX ZNF148 POLR2A MLLT1 GTF2F1 ZSCAN21 TFE3 SP7 TRIM24 ZNF440 GC19P011816 ZNF44 ZNF564 WDR83OS ZNF791 ZNF700 ZNF799 ZNF136 TRIR
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF625-ZNF20 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZNF625-ZNF20 Gene

Genomic Locations for ZNF625-ZNF20 Gene
chr19:12,131,350-12,156,731
(GRCh38/hg38)
Size:
25,382 bases
Orientation:
Minus strand
chr19:12,242,165-12,267,546
(GRCh37/hg19)
Size:
25,382 bases
Orientation:
Minus strand

Genomic View for ZNF625-ZNF20 Gene

Genes around ZNF625-ZNF20 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF625-ZNF20 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF625-ZNF20 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF625-ZNF20 Gene

Proteins for ZNF625-ZNF20 Gene

  • Protein details for ZNF625-ZNF20 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    F2Z3I2-F2Z3I2_HUMAN
    Recommended name:
    ZNF625-ZNF20 readthrough (NMD candidate)
    Protein Accession:
    F2Z3I2

    Protein attributes for ZNF625-ZNF20 Gene

    Size:
    61 amino acids
    Molecular mass:
    7122 Da
    Quaternary structure:
    No Data Available
  • Protein details for ZNF625-ZNF20 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    F8WDT6-F8WDT6_HUMAN
    Recommended name:
    ZNF625-ZNF20 readthrough (NMD candidate)
    Protein Accession:
    F8WDT6

    Protein attributes for ZNF625-ZNF20 Gene

    Size:
    125 amino acids
    Molecular mass:
    14854 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF625-ZNF20 Gene

Post-translational modifications for ZNF625-ZNF20 Gene

No Post-translational modifications

Other Protein References for ZNF625-ZNF20 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ZNF625-ZNF20 Gene

Domains & Families for ZNF625-ZNF20 Gene

Protein Domains for ZNF625-ZNF20 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZNF625-ZNF20: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ZNF625-ZNF20 Gene

Function for ZNF625-ZNF20 Gene

Phenotypes for ZNF625-ZNF20 Gene

genes like me logo Genes that share phenotypes with ZNF625-ZNF20: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF625-ZNF20 Gene

Localization for ZNF625-ZNF20 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ZNF625-ZNF20 Gene

Pathways & Interactions for ZNF625-ZNF20 Gene

PathCards logo

SuperPathways for ZNF625-ZNF20 Gene

No Data Available

Interacting Proteins for ZNF625-ZNF20 Gene

Gene Ontology (GO) - Biological Process for ZNF625-ZNF20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF625-ZNF20: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF625-ZNF20 Gene

Drugs & Compounds for ZNF625-ZNF20 Gene

No Compound Related Data Available

Transcripts for ZNF625-ZNF20 Gene

mRNA/cDNA for ZNF625-ZNF20 Gene

(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(1) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF625-ZNF20 Gene

No ASD Table

Relevant External Links for ZNF625-ZNF20 Gene

GeneLoc Exon Structure for
ZNF625-ZNF20
ECgene alternative splicing isoforms for
ZNF625-ZNF20

Expression for ZNF625-ZNF20 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF625-ZNF20 Gene

genes like me logo Genes that share expression patterns with ZNF625-ZNF20: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF625-ZNF20 Gene

Orthologs for ZNF625-ZNF20 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF625-ZNF20 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Zfp937 35
  • 11 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 8 (a)
ManyToMany
-- 35
  • 8 (a)
ManyToMany
-- 35
  • 8 (a)
ManyToMany
-- 35
  • 8 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 4 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 4 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 4 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii CT573234.2 35
  • 4 (a)
ManyToMany
CR388132.2 35
  • 4 (a)
ManyToMany
Species where no ortholog for ZNF625-ZNF20 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF625-ZNF20 Gene

ENSEMBL:
Gene Tree for ZNF625-ZNF20 (if available)
TreeFam:
Gene Tree for ZNF625-ZNF20 (if available)

Paralogs for ZNF625-ZNF20 Gene

genes like me logo Genes that share paralogs with ZNF625-ZNF20: view

Variants for ZNF625-ZNF20 Gene

Sequence variations from dbSNP and Humsavar for ZNF625-ZNF20 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000003116 -- 12,131,343(-) C/A downstream_transcript_variant
rs1000102253 -- 12,142,358(-) C/G intron_variant
rs1000235145 -- 12,155,970(-) CCCCCC/CCCCCCC intron_variant
rs1000247500 -- 12,150,132(-) A/G intron_variant
rs1000319240 -- 12,149,762(-) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF625-ZNF20 Gene

Variant ID Type Subtype PubMed ID
esv1002859 CNV insertion 20482838
esv2665806 CNV deletion 23128226
nsv578619 CNV loss 21841781
nsv833753 CNV loss 17160897
nsv961178 CNV duplication 23825009
nsv963006 CNV duplication 23825009

Additional Variant Information for ZNF625-ZNF20 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF625-ZNF20

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ZNF625-ZNF20 Gene

Disorders for ZNF625-ZNF20 Gene

Additional Disease Information for ZNF625-ZNF20

No disorders were found for ZNF625-ZNF20 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF625-ZNF20 Gene

Publications for ZNF625-ZNF20 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 13 58

Products for ZNF625-ZNF20 Gene

Sources for ZNF625-ZNF20 Gene

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