This locus represents naturally occurring read-through transcription between the neighboring zinc finger protein 625 (ZNF625) and zinc finger protein 20 (ZNF20) genes on chromosome 19. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2011] See more...

Aliases for ZNF625-ZNF20 Gene

Subcategory (RNA class) for ZNF625-ZNF20 Gene

lncRNA

Number of RNA Genes sources:

2 / 17

Aliases for ZNF625-ZNF20 Gene

  • ZNF625-ZNF20 Readthrough (NMD Candidate) 2 3 5 13
  • Zinc Finger Protein 625 13
  • Lnc-ZNF625-ZNF20-1 165
  • HSALNG0124093 164
  • ZNF625-ZNF20 5
  • ZNF625 13

External Ids for ZNF625-ZNF20 Gene

Previous GeneCards Identifiers for ZNF625-ZNF20 Gene

  • GC19U901507
  • GC19M012246

Summaries for ZNF625-ZNF20 Gene

Entrez Gene Summary for ZNF625-ZNF20 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring zinc finger protein 625 (ZNF625) and zinc finger protein 20 (ZNF20) genes on chromosome 19. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2011]

GeneCards Summary for ZNF625-ZNF20 Gene

ZNF625-ZNF20 (ZNF625-ZNF20 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the lncRNA class. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF433.

Additional gene information for ZNF625-ZNF20 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF625-ZNF20 Gene

Genomics for ZNF625-ZNF20 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZNF625-ZNF20 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF625-ZNF20 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for ZNF625-ZNF20 Gene

Genomic Locations for ZNF625-ZNF20 Gene
chr19:12,131,350-12,156,731
(GRCh38/hg38)
Size:
25,382 bases
Orientation:
Minus strand
chr19:12,242,165-12,267,546
(GRCh37/hg19)
Size:
25,382 bases
Orientation:
Minus strand

Genomic View for ZNF625-ZNF20 Gene

Genes around ZNF625-ZNF20 on UCSC Golden Path with GeneCards custom track
ZNF625-ZNF20 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
ZNF625-ZNF20 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF625-ZNF20 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF625-ZNF20 Gene

Proteins for ZNF625-ZNF20 Gene

  • Protein details for ZNF625-ZNF20 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    F2Z3I2-F2Z3I2_HUMAN
    Recommended name:
    ZNF625-ZNF20 readthrough (NMD candidate)
    Protein Accession:
    F2Z3I2

    Protein attributes for ZNF625-ZNF20 Gene

    Size:
    61 amino acids
    Molecular mass:
    7122 Da
    Quaternary structure:
    No Data Available
  • Protein details for ZNF625-ZNF20 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    F8WDT6-F8WDT6_HUMAN
    Recommended name:
    ZNF625-ZNF20 readthrough (NMD candidate)
    Protein Accession:
    F8WDT6

    Protein attributes for ZNF625-ZNF20 Gene

    Size:
    125 amino acids
    Molecular mass:
    14854 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF625-ZNF20 Gene

Post-translational modifications for ZNF625-ZNF20 Gene

No Post-translational modifications

Other Protein References for ZNF625-ZNF20 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ZNF625-ZNF20 Gene

Domains & Families for ZNF625-ZNF20 Gene

Protein Domains for ZNF625-ZNF20 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with ZNF625-ZNF20: view

No data available for Gene Families , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ZNF625-ZNF20 Gene

Function for ZNF625-ZNF20 Gene

Phenotypes From GWAS Catalog for ZNF625-ZNF20 Gene

Gene Ontology (GO) - Molecular Function for ZNF625-ZNF20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
genes like me logo Genes that share ontologies with ZNF625-ZNF20: view

Phenotypes for ZNF625-ZNF20 Gene

genes like me logo Genes that share phenotypes with ZNF625-ZNF20: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF625-ZNF20 Gene

Localization for ZNF625-ZNF20 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ZNF625-ZNF20 Gene

Pathways & Interactions for ZNF625-ZNF20 Gene

PathCards logo

SuperPathways for ZNF625-ZNF20 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF625-ZNF20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF625-ZNF20: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for ZNF625-ZNF20 Gene

Drugs & Compounds for ZNF625-ZNF20 Gene

No Compound Related Data Available

Transcripts for ZNF625-ZNF20 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for ZNF625-ZNF20 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075EAD5_9606 lncRNA 3418 2

RefSeq: NR_037802,

LNCipedia: lnc-ZNF625-ZNF20-1:2,

URS0000D6D511_9606 lncRNA 545 2

LncBook: HSALNT0255915,

LNCipedia: lnc-ZNF625-ZNF20-1:3,

URS00008BE299_9606 lncRNA 3415 1

LNCipedia: lnc-ZNF625-ZNF20-1:1,

ZNF625-ZNF20 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for ZNF625-ZNF20 Gene

2 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF625-ZNF20 Gene

No ASD Table

Relevant External Links for ZNF625-ZNF20 Gene

GeneLoc Exon Structure for
ZNF625-ZNF20

Expression for ZNF625-ZNF20 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF625-ZNF20 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF625-ZNF20

genes like me logo Genes that share expression patterns with ZNF625-ZNF20: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF625-ZNF20 Gene

Orthologs for ZNF625-ZNF20 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF625-ZNF20 Gene

Organism Taxonomy Gene Similarity Type Details
Mouse
(Mus musculus)
Mammalia Zfp937 31
  • 11 (a)
ManyToMany
Oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 8 (a)
ManyToMany
-- 31
  • 8 (a)
ManyToMany
-- 31
  • 8 (a)
ManyToMany
-- 31
  • 8 (a)
ManyToMany
Chimpanzee
(Pan troglodytes)
Mammalia -- 31
  • 4 (a)
ManyToMany
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 4 (a)
OneToMany
Lizard
(Anolis carolinensis)
Reptilia -- 31
  • 4 (a)
OneToMany
Zebrafish
(Danio rerio)
Actinopterygii CT573234.2 31
  • 4 (a)
ManyToMany
CR388132.2 31
  • 4 (a)
ManyToMany
Species where no ortholog for ZNF625-ZNF20 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for ZNF625-ZNF20 Gene

ENSEMBL:
Gene Tree for ZNF625-ZNF20 (if available)
TreeFam:
Gene Tree for ZNF625-ZNF20 (if available)

Paralogs for ZNF625-ZNF20 Gene

genes like me logo Genes that share paralogs with ZNF625-ZNF20: view

Variants for ZNF625-ZNF20 Gene

Additional dbSNP identifiers (rs#s) for ZNF625-ZNF20 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF625-ZNF20 Gene

Variant ID Type Subtype PubMed ID
esv1002859 CNV insertion 20482838
esv2665806 CNV deletion 23128226
nsv578619 CNV loss 21841781
nsv833753 CNV loss 17160897
nsv961178 CNV duplication 23825009
nsv963006 CNV duplication 23825009

Additional Variant Information for ZNF625-ZNF20 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF625-ZNF20

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for ZNF625-ZNF20 Gene

Disorders for ZNF625-ZNF20 Gene

Additional Disease Information for ZNF625-ZNF20

No disorders were found for ZNF625-ZNF20 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF625-ZNF20 Gene

Publications for ZNF625-ZNF20 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 13
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3

Products for ZNF625-ZNF20 Gene

Sources for ZNF625-ZNF20 Gene