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Aliases for ZNF613 Gene

Aliases for ZNF613 Gene

  • Zinc Finger Protein 613 2 3 5

External Ids for ZNF613 Gene

Previous GeneCards Identifiers for ZNF613 Gene

  • GC19P057123
  • GC19P057125
  • GC19P052430
  • GC19P048761
  • GC19P051879

Summaries for ZNF613 Gene

GeneCards Summary for ZNF613 Gene

ZNF613 (Zinc Finger Protein 613) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF350.

UniProtKB/Swiss-Prot for ZNF613 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF613 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF613 Gene

Genomics for ZNF613 Gene

GeneHancer (GH) Regulatory Elements for ZNF613 Gene

Promoters and enhancers for ZNF613 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I051926 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 576.6 +0.2 163 1.8 PKNOX1 SMAD1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9 POLR2B ZNF613 ZNF611 ZNF577 ZNF137P ZNF841 ZNF350-AS1 ENSG00000268970 ZNF701 ZNF28 ENSG00000269483
GH19I052137 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE 33.6 +212.5 212485 3.3 PKNOX1 FOXA2 SMAD1 ARNT ARID4B SIN3A DMAP1 YY1 POLR2B E2F8 ZNF616 ZNF137P ZNF160 ZNF808 ENSG00000268970 ZNF600 ZNF350 ZNF816 ZNF836 ZNF577
GH19I051393 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE 38 -532.1 -532100 2.8 HDGF PKNOX1 SMAD1 ARNT ZFP64 ARID4B SIN3A IRF4 YY1 POLR2B ENSG00000268889 LOC105372446 ZNF841 ZNF766 ZNF577 ZNF616 ZNF175 ZNF836 ZNF432 ZNF614
GH19I051687 Promoter/Enhancer 2.1 FANTOM5 Ensembl ENCODE dbSUPER 31.2 -236.7 -236656 6.9 HDGF PKNOX1 ARNT SIN3A FEZF1 ZNF2 ZBTB7B E2F8 ZNF207 ZNF143 ZNF137P ZNF808 ZNF841 ZNF616 ZNF766 ZNF577 ENSG00000268970 ZNF836 ENSG00000269825 ZNF175
GH19I052733 Promoter/Enhancer 2.2 EPDnew FANTOM5 Ensembl ENCODE 17.4 +808.1 808096 2.9 HDGF SMAD1 ARID4B SIN3A ZNF48 POLR2B E2F8 ARID2 ATF7 SP3 ZNF611 ZNF701 ZNF137P ENSG00000268970 ENSG00000269001 ZNF845 ZNF808 ZNF160 ZNF525 ZNF816
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF613 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF613 gene promoter:

Genomic Locations for ZNF613 Gene

Genomic Locations for ZNF613 Gene
chr19:51,927,147-51,948,759
(GRCh38/hg38)
Size:
21,613 bases
Orientation:
Plus strand
chr19:52,430,400-52,452,012
(GRCh37/hg19)

Genomic View for ZNF613 Gene

Genes around ZNF613 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF613 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF613 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF613 Gene

Proteins for ZNF613 Gene

  • Protein details for ZNF613 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6PF04-ZN613_HUMAN
    Recommended name:
    Zinc finger protein 613
    Protein Accession:
    Q6PF04
    Secondary Accessions:
    • Q96SS9

    Protein attributes for ZNF613 Gene

    Size:
    617 amino acids
    Molecular mass:
    70143 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF613 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF613 Gene

Post-translational modifications for ZNF613 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF613 Gene

Domains & Families for ZNF613 Gene

Gene Families for ZNF613 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Suggested Antigen Peptide Sequences for ZNF613 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6PF04

UniProtKB/Swiss-Prot:

ZN613_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF613: view

Function for ZNF613 Gene

Molecular function for ZNF613 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF613 Gene

Gene Ontology (GO) - Molecular Function for ZNF613 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0044212 transcription regulatory region DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF613: view
genes like me logo Genes that share phenotypes with ZNF613: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF613 Gene

Localization for ZNF613 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF613 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF613 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF613 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF613: view

Pathways & Interactions for ZNF613 Gene

SuperPathways for ZNF613 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF613: view

Pathways by source for ZNF613 Gene

2 Reactome pathways for ZNF613 Gene

Interacting Proteins for ZNF613 Gene

Gene Ontology (GO) - Biological Process for ZNF613 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription by RNA polymerase II IBA --
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0045944 positive regulation of transcription by RNA polymerase II IBA --
genes like me logo Genes that share ontologies with ZNF613: view

No data available for SIGNOR curated interactions for ZNF613 Gene

Drugs & Compounds for ZNF613 Gene

No Compound Related Data Available

Transcripts for ZNF613 Gene

Unigene Clusters for ZNF613 Gene

Zinc finger protein 613:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF613 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c · 8d
SP1: - - - -
SP2: - -
SP3: - - - -
SP4: - - - - -
SP5: - - - -
SP6: - -
SP7: - - - -
SP8:
SP9: - - - - - -

Relevant External Links for ZNF613 Gene

GeneLoc Exon Structure for
ZNF613
ECgene alternative splicing isoforms for
ZNF613

Expression for ZNF613 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF613 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of ZNF613 Gene:

ZNF613

SOURCE GeneReport for Unigene cluster for ZNF613 Gene:

Hs.183390
genes like me logo Genes that share expression patterns with ZNF613: view

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF613 Gene

Orthologs for ZNF613 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF613 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF613 33 34
  • 99.68 (n)
dog
(Canis familiaris)
Mammalia ZNF613 33 34
  • 84.36 (n)
cow
(Bos Taurus)
Mammalia ZNF613 33 34
  • 82.36 (n)
mouse
(Mus musculus)
Mammalia Zfp157 33 16
  • 59.86 (n)
rat
(Rattus norvegicus)
Mammalia Zfp157 33
  • 59.48 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 46 (a)
ManyToMany
-- 34
  • 45 (a)
ManyToMany
-- 34
  • 45 (a)
ManyToMany
-- 34
  • 45 (a)
ManyToMany
-- 34
  • 44 (a)
ManyToMany
-- 34
  • 43 (a)
ManyToMany
-- 34
  • 42 (a)
ManyToMany
-- 34
  • 40 (a)
ManyToMany
-- 34
  • 39 (a)
ManyToMany
-- 34
  • 38 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 39 (a)
OneToMany
Species where no ortholog for ZNF613 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF613 Gene

ENSEMBL:
Gene Tree for ZNF613 (if available)
TreeFam:
Gene Tree for ZNF613 (if available)

Paralogs for ZNF613 Gene

Paralogs for ZNF613 Gene

(513) SIMAP similar genes for ZNF613 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF613: view

Variants for ZNF613 Gene

Sequence variations from dbSNP and Humsavar for ZNF613 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000012452 -- 51,941,168(+) G/A intron_variant
rs1000263281 -- 51,926,070(+) T/A upstream_transcript_variant
rs1000293806 -- 51,939,196(+) C/T intron_variant
rs1000453558 -- 51,932,455(+) G/T intron_variant
rs1000642831 -- 51,938,860(+) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF613 Gene

Variant ID Type Subtype PubMed ID
dgv1067e212 CNV gain 25503493
dgv143e55 CNV gain 17911159
dgv3626n100 CNV gain 25217958
dgv425n27 CNV gain 19166990
dgv6523n54 CNV gain 21841781
esv2758767 CNV gain+loss 17122850
esv3644680 CNV gain 21293372
nsv1140251 OTHER inversion 24896259
nsv580001 CNV gain 21841781
nsv580005 CNV loss 21841781
nsv833872 CNV loss 17160897

Variation tolerance for ZNF613 Gene

Residual Variation Intolerance Score: 49.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.44; 42.98% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF613 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF613

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF613 Gene

Disorders for ZNF613 Gene

Additional Disease Information for ZNF613

No disorders were found for ZNF613 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF613 Gene

Publications for ZNF613 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58

Products for ZNF613 Gene

Sources for ZNF613 Gene

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