Aliases for ZNF611 Gene

Aliases for ZNF611 Gene

  • Zinc Finger Protein 611 2 3 4 5

External Ids for ZNF611 Gene

Previous GeneCards Identifiers for ZNF611 Gene

  • GC19M057899
  • GC19M057897
  • GC19M053207
  • GC19M049535

Summaries for ZNF611 Gene

GeneCards Summary for ZNF611 Gene

ZNF611 (Zinc Finger Protein 611) is a Protein Coding gene. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity. An important paralog of this gene is ZNF600.

UniProtKB/Swiss-Prot Summary for ZNF611 Gene

Additional gene information for ZNF611 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF611 Gene

Genomics for ZNF611 Gene

GeneHancer (GH) Regulatory Elements for ZNF611 Gene

Promoters and enhancers for ZNF611 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF611 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF611

Genomic Locations for ZNF611 Gene

Genomic Locations for ZNF611 Gene
32,261 bases
Minus strand
32,261 bases
Minus strand

Genomic View for ZNF611 Gene

Genes around ZNF611 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF611 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF611 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF611 Gene

Proteins for ZNF611 Gene

  • Protein details for ZNF611 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 611
    Protein Accession:
    Secondary Accessions:
    • B3KRD5
    • Q69YG9

    Protein attributes for ZNF611 Gene

    705 amino acids
    Molecular mass:
    81449 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF611 Gene


neXtProt entry for ZNF611 Gene

Post-translational modifications for ZNF611 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF611 Gene

Domains & Families for ZNF611 Gene

Gene Families for ZNF611 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF611 Gene

  • C2H2-type zinc finger signature
  • KRAB box

Suggested Antigen Peptide Sequences for ZNF611 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 611 (ZN611_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF611: view

Function for ZNF611 Gene

Molecular function for ZNF611 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF611 Gene

Gene Ontology (GO) - Molecular Function for ZNF611 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF611: view
genes like me logo Genes that share phenotypes with ZNF611: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF611 Gene

Localization for ZNF611 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF611 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF611 gene
Compartment Confidence
nucleus 4
peroxisome 1
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for ZNF611 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF611: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF611 Gene

Pathways & Interactions for ZNF611 Gene

genes like me logo Genes that share pathways with ZNF611: view

Pathways by source for ZNF611 Gene

2 Reactome pathways for ZNF611 Gene
1 KEGG pathway for ZNF611 Gene

Interacting Proteins for ZNF611 Gene


Gene Ontology (GO) - Biological Process for ZNF611 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF611: view

No data available for SIGNOR curated interactions for ZNF611 Gene

Drugs & Compounds for ZNF611 Gene

No Compound Related Data Available

Transcripts for ZNF611 Gene

mRNA/cDNA for ZNF611 Gene

14 NCBI additional mRNA sequence :
21 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF611 Gene

No ASD Table

Relevant External Links for ZNF611 Gene

GeneLoc Exon Structure for

Expression for ZNF611 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF611 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF611

SOURCE GeneReport for Unigene cluster for ZNF611 Gene:


Evidence on tissue expression from TISSUES for ZNF611 Gene

  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZNF611: view

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF611 Gene

Orthologs for ZNF611 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF611 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF611 30
  • 99.05 (n)
-- 31
  • 79 (a)
(Canis familiaris)
Mammalia -- 31
  • 50 (a)
(Bos Taurus)
Mammalia -- 31
  • 45 (a)
Species where no ortholog for ZNF611 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF611 Gene

Gene Tree for ZNF611 (if available)
Gene Tree for ZNF611 (if available)
Evolutionary constrained regions (ECRs) for ZNF611: view image

Paralogs for ZNF611 Gene

Paralogs for ZNF611 Gene

(528) SIMAP similar genes for ZNF611 Gene using alignment to 7 proteins:

  • ZN611_HUMAN
  • M0R1T1_HUMAN
  • M0R2W3_HUMAN
genes like me logo Genes that share paralogs with ZNF611: view

Variants for ZNF611 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF611 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs34846371 - p.Pro252Ile
rs3884051 - p.Asn234Ile
rs4085565 - p.Pro252Thr
rs4085566 - p.Pro252Leu
rs4087790 - p.Glu340Gly

Additional dbSNP identifiers (rs#s) for ZNF611 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF611 Gene

Variant ID Type Subtype PubMed ID
dgv3628n100 CNV gain 25217958
esv1709802 CNV insertion 17803354
esv2599883 CNV deletion 19546169
esv2671531 CNV deletion 23128226
esv2718786 CNV deletion 23290073
esv2718787 CNV deletion 23290073
esv2718794 CNV deletion 23290073
esv2718796 CNV deletion 23290073
esv2718797 CNV deletion 23290073
esv3556574 CNV deletion 23714750
esv3644714 CNV gain 21293372
esv3644715 CNV loss 21293372
esv3644716 CNV gain 21293372
esv3644717 CNV loss 21293372
esv3893231 CNV loss 25118596
esv3893233 CNV loss 25118596
esv3893234 CNV gain 25118596
esv7362 CNV loss 19470904
nsv1055617 CNV loss 25217958
nsv1057118 CNV gain 25217958
nsv1062976 CNV gain 25217958
nsv1066762 CNV gain 25217958
nsv1067557 CNV gain 25217958
nsv1078889 OTHER inversion 25765185
nsv1140479 CNV deletion 24896259
nsv1146332 OTHER inversion 26484159
nsv458744 CNV gain 19166990
nsv458745 CNV gain 19166990
nsv470152 CNV gain 18288195
nsv509752 CNV insertion 20534489
nsv521828 CNV loss 19592680
nsv580028 CNV gain 21841781
nsv580030 CNV gain 21841781
nsv580031 CNV gain 21841781
nsv833874 CNV loss 17160897
nsv833875 CNV loss 17160897
nsv961238 CNV duplication 23825009
nsv961239 CNV duplication 23825009

Variation tolerance for ZNF611 Gene

Residual Variation Intolerance Score: 91% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.05; 87.54% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF611 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF611 Gene

Disorders for ZNF611 Gene

Additional Disease Information for ZNF611

No disorders were found for ZNF611 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF611 Gene

Publications for ZNF611 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 54
  3. VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3 54
  4. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 54
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 54

Products for ZNF611 Gene

Sources for ZNF611 Gene