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Aliases for ZNF611 Gene

Aliases for ZNF611 Gene

  • Zinc Finger Protein 611 2 3 5

External Ids for ZNF611 Gene

Previous GeneCards Identifiers for ZNF611 Gene

  • GC19M057899
  • GC19M057897
  • GC19M053207
  • GC19M049535

Summaries for ZNF611 Gene

GeneCards Summary for ZNF611 Gene

ZNF611 (Zinc Finger Protein 611) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA binding transcription factor activity. An important paralog of this gene is ZNF808.

UniProtKB/Swiss-Prot for ZNF611 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF611 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF611 Gene

Genomics for ZNF611 Gene

GeneHancer (GH) Regulatory Elements for ZNF611 Gene

Promoters and enhancers for ZNF611 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I052733 Promoter/Enhancer 2.2 EPDnew FANTOM5 Ensembl ENCODE 573.4 -0.2 -170 2.9 HDGF SMAD1 ARID4B SIN3A ZNF48 POLR2B E2F8 ARID2 ATF7 SP3 ZNF611 ZNF701 ZNF137P ENSG00000268970 ENSG00000269001 ZNF845 ZNF808 ZNF160 ZNF525 ZNF816
GH19I052712 Promoter 0.5 EPDnew 550.3 +22.6 22562 0.1 ZNF611 PIR41908
GH19I052137 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE 20.7 +595.4 595441 3.3 PKNOX1 FOXA2 SMAD1 ARNT ARID4B SIN3A DMAP1 YY1 POLR2B E2F8 ZNF616 ZNF137P ZNF160 ZNF808 ENSG00000268970 ZNF600 ZNF350 ZNF816 ZNF836 ZNF577
GH19I053517 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 23.5 -784.5 -784541 4.8 PKNOX1 SMAD1 ARNT ARID4B SIN3A YY1 ZNF766 E2F8 ZNF143 KLF13 ZNF331 ZNF137P LENG8 ZNF525 LENG8-AS1 PRPF31 CNOT3 ZNF160 ZNF701 ZNF83
GH19I052526 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 22.9 +207.4 207358 2.4 HDGF ATF1 ARID4B SIN3A YBX1 GLI4 ZNF48 POLR2B CBX5 ZNF416 ZNF808 ZNF611 ZNF613 ZNF137P ZNF701 ENSG00000268970 ENSG00000269001 TPM3P9 ZNF665 ZNF525
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF611 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZNF611 Gene

Genomic Locations for ZNF611 Gene
chr19:52,702,813-52,735,073
(GRCh38/hg38)
Size:
32,261 bases
Orientation:
Minus strand
chr19:53,206,066-53,238,326
(GRCh37/hg19)

Genomic View for ZNF611 Gene

Genes around ZNF611 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF611 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF611 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF611 Gene

Proteins for ZNF611 Gene

  • Protein details for ZNF611 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N823-ZN611_HUMAN
    Recommended name:
    Zinc finger protein 611
    Protein Accession:
    Q8N823
    Secondary Accessions:
    • B3KRD5
    • Q69YG9

    Protein attributes for ZNF611 Gene

    Size:
    705 amino acids
    Molecular mass:
    81449 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF611 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF611 Gene

Post-translational modifications for ZNF611 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF611 Gene

Domains & Families for ZNF611 Gene

Gene Families for ZNF611 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Suggested Antigen Peptide Sequences for ZNF611 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N823

UniProtKB/Swiss-Prot:

ZN611_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF611: view

Function for ZNF611 Gene

Molecular function for ZNF611 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF611 Gene

Gene Ontology (GO) - Molecular Function for ZNF611 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF611: view
genes like me logo Genes that share phenotypes with ZNF611: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF611 Gene

Localization for ZNF611 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF611 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF611 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF611 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF611: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF611 Gene

Pathways & Interactions for ZNF611 Gene

SuperPathways for ZNF611 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF611: view

Pathways by source for ZNF611 Gene

2 Reactome pathways for ZNF611 Gene

Gene Ontology (GO) - Biological Process for ZNF611 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF611: view

No data available for SIGNOR curated interactions for ZNF611 Gene

Drugs & Compounds for ZNF611 Gene

No Compound Related Data Available

Transcripts for ZNF611 Gene

mRNA/cDNA for ZNF611 Gene

Unigene Clusters for ZNF611 Gene

Zinc finger protein 611:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF611 Gene

No ASD Table

Relevant External Links for ZNF611 Gene

GeneLoc Exon Structure for
ZNF611
ECgene alternative splicing isoforms for
ZNF611

Expression for ZNF611 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF611 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of ZNF611 Gene:

ZNF611

SOURCE GeneReport for Unigene cluster for ZNF611 Gene:

Hs.143951

Evidence on tissue expression from TISSUES for ZNF611 Gene

  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZNF611: view

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF611 Gene

Orthologs for ZNF611 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF611 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF611 33
  • 99.05 (n)
-- 34
  • 79 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 34
  • 50 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 34
  • 45 (a)
ManyToMany
Species where no ortholog for ZNF611 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF611 Gene

ENSEMBL:
Gene Tree for ZNF611 (if available)
TreeFam:
Gene Tree for ZNF611 (if available)

Paralogs for ZNF611 Gene

(528) SIMAP similar genes for ZNF611 Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with ZNF611: view

Variants for ZNF611 Gene

Sequence variations from dbSNP and Humsavar for ZNF611 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000010703 -- 52,713,600(-) A/C intron_variant
rs1000029874 -- 52,734,911(-) T/C/G genic_upstream_transcript_variant, intron_variant
rs1000035996 -- 52,734,130(-) A/G genic_upstream_transcript_variant, intron_variant
rs1000063247 -- 52,713,800(-) A/G intron_variant
rs1000111104 -- 52,733,167(-) G/A genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF611 Gene

Variant ID Type Subtype PubMed ID
dgv3628n100 CNV gain 25217958
esv1709802 CNV insertion 17803354
esv2599883 CNV deletion 19546169
esv2671531 CNV deletion 23128226
esv2718786 CNV deletion 23290073
esv2718787 CNV deletion 23290073
esv2718794 CNV deletion 23290073
esv2718796 CNV deletion 23290073
esv2718797 CNV deletion 23290073
esv3556574 CNV deletion 23714750
esv3644714 CNV gain 21293372
esv3644715 CNV loss 21293372
esv3644716 CNV gain 21293372
esv3644717 CNV loss 21293372
esv3893231 CNV loss 25118596
esv3893233 CNV loss 25118596
esv3893234 CNV gain 25118596
esv7362 CNV loss 19470904
nsv1055617 CNV loss 25217958
nsv1057118 CNV gain 25217958
nsv1062976 CNV gain 25217958
nsv1066762 CNV gain 25217958
nsv1067557 CNV gain 25217958
nsv1078889 OTHER inversion 25765185
nsv1140479 CNV deletion 24896259
nsv1146332 OTHER inversion 26484159
nsv458744 CNV gain 19166990
nsv458745 CNV gain 19166990
nsv470152 CNV gain 18288195
nsv509752 CNV insertion 20534489
nsv521828 CNV loss 19592680
nsv580028 CNV gain 21841781
nsv580030 CNV gain 21841781
nsv580031 CNV gain 21841781
nsv833874 CNV loss 17160897
nsv833875 CNV loss 17160897
nsv961238 CNV duplication 23825009
nsv961239 CNV duplication 23825009

Variation tolerance for ZNF611 Gene

Residual Variation Intolerance Score: 91% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.05; 87.54% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF611 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF611

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF611 Gene

Disorders for ZNF611 Gene

Additional Disease Information for ZNF611

No disorders were found for ZNF611 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF611 Gene

Publications for ZNF611 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  3. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  4. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 58
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58

Products for ZNF611 Gene

Sources for ZNF611 Gene

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