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Aliases for ZNF610 Gene

Aliases for ZNF610 Gene

  • Zinc Finger Protein 610 2 3 5

External Ids for ZNF610 Gene

Previous GeneCards Identifiers for ZNF610 Gene

  • GC19P057540
  • GC19P052839
  • GC19P049169

Summaries for ZNF610 Gene

GeneCards Summary for ZNF610 Gene

ZNF610 (Zinc Finger Protein 610) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF480.

UniProtKB/Swiss-Prot for ZNF610 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF610 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF610 Gene

Genomics for ZNF610 Gene

GeneHancer (GH) Regulatory Elements for ZNF610 Gene

Promoters and enhancers for ZNF610 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I052335 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE 550.8 +4.7 4676 1.8 ARID4B SIN3A ZNF335 ELK1 RUNX3 THAP11 ZNF362 SP3 CBFB REST ZNF610 ZNF480 ZNF528 ENSG00000269535
GH19I052345 Promoter 0.8 EPDnew 550.4 +13.5 13547 0.1 ATF1 RFX1 CREB1 ATF7 CREM ATF2 ENSG00000269535 ZNF610 ZNF83 ZNF880
GH19I052344 Promoter 0.6 EPDnew 550.4 +12.4 12353 0.1 ZNF335 ENSG00000269535 ZNF610 ZNF528-AS1
GH19I051393 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE 39.2 -936.8 -936816 2.8 HDGF PKNOX1 SMAD1 ARNT ZFP64 ARID4B SIN3A IRF4 YY1 POLR2B ENSG00000268889 LOC105372446 ZNF841 ZNF766 ZNF577 ZNF616 ZNF175 ZNF836 ZNF432 ZNF614
GH19I051687 Promoter/Enhancer 2.1 FANTOM5 Ensembl ENCODE dbSUPER 19.4 -641.4 -641372 6.9 HDGF PKNOX1 ARNT SIN3A FEZF1 ZNF2 ZBTB7B E2F8 ZNF207 ZNF143 ZNF137P ZNF808 ZNF841 ZNF616 ZNF766 ZNF577 ENSG00000268970 ZNF836 ENSG00000269825 ZNF175
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF610 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF610 gene promoter:

Genomic Locations for ZNF610 Gene

Genomic Locations for ZNF610 Gene
chr19:52,331,863-52,367,778
(GRCh38/hg38)
Size:
35,916 bases
Orientation:
Plus strand
chr19:52,839,498-52,871,031
(GRCh37/hg19)

Genomic View for ZNF610 Gene

Genes around ZNF610 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF610 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF610 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF610 Gene

Proteins for ZNF610 Gene

  • Protein details for ZNF610 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N9Z0-ZN610_HUMAN
    Recommended name:
    Zinc finger protein 610
    Protein Accession:
    Q8N9Z0
    Secondary Accessions:
    • A8K4C3
    • Q86YH8
    • Q8NDS9

    Protein attributes for ZNF610 Gene

    Size:
    462 amino acids
    Molecular mass:
    53489 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF610 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF610 Gene

Post-translational modifications for ZNF610 Gene

  • Ubiquitination at isoforms=2412
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ZNF610 Gene

Domains & Families for ZNF610 Gene

Gene Families for ZNF610 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF610 Gene

Suggested Antigen Peptide Sequences for ZNF610 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N9Z0

UniProtKB/Swiss-Prot:

ZN610_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF610: view

Function for ZNF610 Gene

Molecular function for ZNF610 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF610 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF610: view
genes like me logo Genes that share phenotypes with ZNF610: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF610 Gene

Localization for ZNF610 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF610 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF610 gene
Compartment Confidence
nucleus 5
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF610 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF610: view

Pathways & Interactions for ZNF610 Gene

SuperPathways for ZNF610 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF610: view

Pathways by source for ZNF610 Gene

2 Reactome pathways for ZNF610 Gene

Interacting Proteins for ZNF610 Gene

Gene Ontology (GO) - Biological Process for ZNF610 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF610: view

No data available for SIGNOR curated interactions for ZNF610 Gene

Drugs & Compounds for ZNF610 Gene

No Compound Related Data Available

Transcripts for ZNF610 Gene

Unigene Clusters for ZNF610 Gene

Zinc finger protein 610:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF610 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b
SP1: -
SP2: - -
SP3:

Relevant External Links for ZNF610 Gene

GeneLoc Exon Structure for
ZNF610
ECgene alternative splicing isoforms for
ZNF610

Expression for ZNF610 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF610 Gene

Protein differential expression in normal tissues from HIPED for ZNF610 Gene

This gene is overexpressed in Heart (51.6) and Platelet (17.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF610 Gene



Protein tissue co-expression partners for ZNF610 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF610 Gene:

ZNF610

SOURCE GeneReport for Unigene cluster for ZNF610 Gene:

Hs.147025

Evidence on tissue expression from TISSUES for ZNF610 Gene

  • Nervous system(4.2)
  • Eye(4)
  • Skin(4)
genes like me logo Genes that share expression patterns with ZNF610: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF610 Gene

Orthologs for ZNF610 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF610 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF610 33
  • 99.28 (n)
-- 34
  • 87 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 34
  • 41 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 34
  • 32 (a)
ManyToMany
Species where no ortholog for ZNF610 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF610 Gene

ENSEMBL:
Gene Tree for ZNF610 (if available)
TreeFam:
Gene Tree for ZNF610 (if available)

Paralogs for ZNF610 Gene

(501) SIMAP similar genes for ZNF610 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for ZNF610 Gene

genes like me logo Genes that share paralogs with ZNF610: view

Variants for ZNF610 Gene

Sequence variations from dbSNP and Humsavar for ZNF610 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000049927 -- 52,351,929(+) C/G intron_variant
rs1000140129 -- 52,362,925(+) A/C intron_variant
rs1000148420 -- 52,356,490(+) T/C intron_variant
rs1000232582 -- 52,342,451(+) A/G genic_upstream_transcript_variant, intron_variant
rs1000280489 -- 52,341,240(+) T/C genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF610 Gene

Variant ID Type Subtype PubMed ID
esv21813 CNV gain 19812545
esv2600634 CNV deletion 19546169
esv2660483 CNV deletion 23128226
esv2671354 CNV deletion 23128226
esv3644690 CNV loss 21293372
nsv1140251 OTHER inversion 24896259
nsv2536 CNV deletion 18451855
nsv458742 CNV loss 19166990
nsv580008 CNV loss 21841781
nsv833873 CNV gain 17160897
nsv963069 CNV duplication 23825009

Variation tolerance for ZNF610 Gene

Residual Variation Intolerance Score: 86.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.81; 34.15% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF610 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF610

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF610 Gene

Disorders for ZNF610 Gene

Additional Disease Information for ZNF610

No disorders were found for ZNF610 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF610 Gene

Publications for ZNF610 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  5. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 58

Products for ZNF610 Gene

Sources for ZNF610 Gene

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