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Aliases for ZNF607 Gene

Aliases for ZNF607 Gene

  • Zinc Finger Protein 607 2 3 5

External Ids for ZNF607 Gene

Previous GeneCards Identifiers for ZNF607 Gene

  • GC19M042880
  • GC19M042881
  • GC19M038187
  • GC19M034637

Summaries for ZNF607 Gene

GeneCards Summary for ZNF607 Gene

ZNF607 (Zinc Finger Protein 607) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA binding transcription factor activity. An important paralog of this gene is ZNF780B.

UniProtKB/Swiss-Prot for ZNF607 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF607 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF607 Gene

Genomics for ZNF607 Gene

GeneHancer (GH) Regulatory Elements for ZNF607 Gene

Promoters and enhancers for ZNF607 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I037718 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 586.5 +0.4 385 2 ARID4B SIN3A DMAP1 ZNF2 SLC30A9 POLR2B ZNF213 ZNF302 ZNF207 ZNF143 ZNF607 ENSG00000267552 ZNF527 ZFP30 ZNF571 ZNF790 HKR1 ZNF585B ZNF585A ZNF420
GH19I037593 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 154.5 +125.1 125089 2.2 PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 IRF4 YY1 SLC30A9 ZNF213 ZNF571 ZNF540 ZNF567 ZNF527 ZFP30 ZNF383 HKR1 ZNF345 ZNF585A ZNF607
GH19I037653 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 133.3 +64.5 64490 3 MLX ZFP64 FEZF1 DMAP1 YY1 ZNF213 ZNF416 ZNF143 ZNF548 SP3 ZFP30 ZNF527 ZNF567 ZNF383 ZNF345 ZNF571 ZNF790 HKR1 ZNF850 ZNF585A
GH19I037370 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 127.4 +348.8 348750 1.9 HDGF PKNOX1 SMAD1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 ZNF213 ZNF527 ZNF567 ZNF383 ZNF345 ZFP30 ZNF571 HKR1 ZNF850 ZNF793 ZNF790
GH19I036915 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE 98.8 +803.3 803295 2.2 PKNOX1 ARID4B SIN3A ZNF2 YY1 ZNF302 ZNF416 ZNF143 ZNF548 SP3 ZNF568 ZNF829 GC19M038851 ZNF527 ZNF567 ZNF345 ZNF383 ZFP30 ZNF571 ZNF850
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF607 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF607 gene promoter:

Genomic Locations for ZNF607 Gene

Genomic Locations for ZNF607 Gene
chr19:37,696,363-37,719,790
(GRCh38/hg38)
Size:
23,428 bases
Orientation:
Minus strand
chr19:38,187,264-38,210,691
(GRCh37/hg19)

Genomic View for ZNF607 Gene

Genes around ZNF607 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF607 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF607 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF607 Gene

Proteins for ZNF607 Gene

  • Protein details for ZNF607 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96SK3-ZN607_HUMAN
    Recommended name:
    Zinc finger protein 607
    Protein Accession:
    Q96SK3
    Secondary Accessions:
    • F5H141
    • Q6ZMN2
    • Q6ZMN4
    • Q96C40

    Protein attributes for ZNF607 Gene

    Size:
    696 amino acids
    Molecular mass:
    80507 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF607 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF607 Gene

Post-translational modifications for ZNF607 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ZNF607 Gene

Domains & Families for ZNF607 Gene

Gene Families for ZNF607 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Suggested Antigen Peptide Sequences for ZNF607 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96SK3

UniProtKB/Swiss-Prot:

ZN607_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF607: view

Function for ZNF607 Gene

Molecular function for ZNF607 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF607 Gene

Gene Ontology (GO) - Molecular Function for ZNF607 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0005515 protein binding IPI 16189514
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF607: view
genes like me logo Genes that share phenotypes with ZNF607: view

miRNA for ZNF607 Gene

miRTarBase miRNAs that target ZNF607

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF607 Gene

Localization for ZNF607 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF607 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF607 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF607 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF607: view

Pathways & Interactions for ZNF607 Gene

SuperPathways for ZNF607 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF607: view

Pathways by source for ZNF607 Gene

2 Reactome pathways for ZNF607 Gene

Gene Ontology (GO) - Biological Process for ZNF607 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
genes like me logo Genes that share ontologies with ZNF607: view

No data available for SIGNOR curated interactions for ZNF607 Gene

Drugs & Compounds for ZNF607 Gene

No Compound Related Data Available

Transcripts for ZNF607 Gene

Unigene Clusters for ZNF607 Gene

Zinc finger protein 607:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF607 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e
SP1: - - -
SP2: -
SP3:
SP4: - -
SP5: - -
SP6: - - -

Relevant External Links for ZNF607 Gene

GeneLoc Exon Structure for
ZNF607
ECgene alternative splicing isoforms for
ZNF607

Expression for ZNF607 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF607 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF607 Gene

This gene is overexpressed in Testis (x8.1).

Protein differential expression in normal tissues from HIPED for ZNF607 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (60.3) and Heart (8.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF607 Gene



Protein tissue co-expression partners for ZNF607 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF607 Gene:

ZNF607

SOURCE GeneReport for Unigene cluster for ZNF607 Gene:

Hs.116622
genes like me logo Genes that share expression patterns with ZNF607: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF607 Gene

Orthologs for ZNF607 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF607 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF607 33
  • 99.62 (n)
cow
(Bos Taurus)
Mammalia LOC787397 33
  • 74.08 (n)
dog
(Canis familiaris)
Mammalia LOC102156679 33
  • 73.63 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 46 (a)
OneToMany
-- 34
  • 45 (a)
OneToMany
-- 34
  • 44 (a)
OneToMany
-- 34
  • 44 (a)
OneToMany
-- 34
  • 44 (a)
OneToMany
-- 34
  • 43 (a)
OneToMany
-- 34
  • 43 (a)
OneToMany
-- 34
  • 43 (a)
OneToMany
-- 34
  • 42 (a)
OneToMany
-- 34
  • 42 (a)
OneToMany
-- 34
  • 42 (a)
OneToMany
-- 34
  • 42 (a)
OneToMany
-- 34
  • 42 (a)
OneToMany
-- 34
  • 42 (a)
OneToMany
-- 34
  • 42 (a)
OneToMany
-- 34
  • 41 (a)
OneToMany
-- 34
  • 41 (a)
OneToMany
-- 34
  • 41 (a)
OneToMany
-- 34
  • 41 (a)
OneToMany
-- 34
  • 41 (a)
OneToMany
-- 34
  • 40 (a)
OneToMany
-- 34
  • 39 (a)
OneToMany
-- 34
  • 39 (a)
OneToMany
-- 34
  • 39 (a)
OneToMany
-- 34
  • 39 (a)
OneToMany
-- 34
  • 39 (a)
OneToMany
-- 34
  • 38 (a)
OneToMany
-- 34
  • 38 (a)
OneToMany
-- 34
  • 38 (a)
OneToMany
-- 34
  • 37 (a)
OneToMany
-- 34
  • 37 (a)
OneToMany
-- 34
  • 36 (a)
OneToMany
-- 34
  • 35 (a)
OneToMany
-- 34
  • 35 (a)
OneToMany
-- 34
  • 35 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm13051 34
  • 41 (a)
OneToMany
Gm13150 34
  • 41 (a)
OneToMany
Gm13151 34
  • 40 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia ZNF607 34
  • 40 (a)
OneToOne
Species where no ortholog for ZNF607 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF607 Gene

ENSEMBL:
Gene Tree for ZNF607 (if available)
TreeFam:
Gene Tree for ZNF607 (if available)

Paralogs for ZNF607 Gene

Paralogs for ZNF607 Gene

(528) SIMAP similar genes for ZNF607 Gene using alignment to 5 proteins:

Pseudogenes.org Pseudogenes for ZNF607 Gene

genes like me logo Genes that share paralogs with ZNF607: view

Variants for ZNF607 Gene

Sequence variations from dbSNP and Humsavar for ZNF607 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000015421 -- 37,707,644(-) G/C intron_variant
rs1000033135 -- 37,717,639(-) T/A intron_variant
rs1000039084 -- 37,717,535(-) C/A intron_variant
rs1000343345 -- 37,705,270(-) T/C intron_variant
rs1000486567 -- 37,720,503(-) A/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF607 Gene

Variant ID Type Subtype PubMed ID
nsv579468 CNV gain 21841781
nsv833820 CNV loss 17160897
nsv978813 CNV duplication 23825009

Variation tolerance for ZNF607 Gene

Residual Variation Intolerance Score: 46% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.39; 81.75% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF607 Gene

Human Gene Mutation Database (HGMD)
ZNF607
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF607

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF607 Gene

Disorders for ZNF607 Gene

Additional Disease Information for ZNF607

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for ZNF607 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF607 Gene

Publications for ZNF607 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 2 3 4 58
  2. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PMID: 19851296) Oguri M … Yamada Y (American journal of hypertension 2010) 3 44 58
  3. Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PMID: 20198315) Yoshida T … Yamada Y (International journal of molecular medicine 2010) 3 44 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58

Products for ZNF607 Gene

Sources for ZNF607 Gene

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