Aliases for ZNF585A Gene

Aliases for ZNF585A Gene

  • Zinc Finger Protein 585A 2 3 4 5
  • Zfp27 3

External Ids for ZNF585A Gene

Previous GeneCards Identifiers for ZNF585A Gene

  • GC19M042334
  • GC19M042337
  • GC19M042289
  • GC19M037597
  • GC19M034110
  • GC19M037109
  • GC19M037114
  • GC19M039007
  • GC19M039148
  • GC19M039212
  • GC19M037325
  • GC19M037386
  • GC19M037423
  • GC19M037750
  • GC19M038051
  • GC19M038341
  • GC19M038636
  • GC19M038879

Summaries for ZNF585A Gene

GeneCards Summary for ZNF585A Gene

ZNF585A (Zinc Finger Protein 585A) is a Protein Coding gene. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity. An important paralog of this gene is ZNF585B.

UniProtKB/Swiss-Prot Summary for ZNF585A Gene

Additional gene information for ZNF585A Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF585A Gene

Genomics for ZNF585A Gene

GeneHancer (GH) Regulatory Elements for ZNF585A Gene

Promoters and enhancers for ZNF585A Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF585A on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF585A

Top Transcription factor binding sites by QIAGEN in the ZNF585A gene promoter:
  • POU6F1 (c2)

Genomic Locations for ZNF585A Gene

Genomic Locations for ZNF585A Gene
chr19:37,106,734-37,172,741
(GRCh38/hg38)
Size:
66,008 bases
Orientation:
Minus strand
chr19:37,597,636-37,663,643
(GRCh37/hg19)
Size:
66,008 bases
Orientation:
Minus strand

Genomic View for ZNF585A Gene

Genes around ZNF585A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF585A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF585A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF585A Gene

Proteins for ZNF585A Gene

  • Protein details for ZNF585A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P3V2-Z585A_HUMAN
    Recommended name:
    Zinc finger protein 585A
    Protein Accession:
    Q6P3V2
    Secondary Accessions:
    • Q8TE95
    • Q96MV3

    Protein attributes for ZNF585A Gene

    Size:
    769 amino acids
    Molecular mass:
    87974 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB85057.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF585A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF585A Gene

Post-translational modifications for ZNF585A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF585A Gene

No data available for DME Specific Peptides for ZNF585A Gene

Domains & Families for ZNF585A Gene

Gene Families for ZNF585A Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF585A Gene

Blocks:
  • KRAB box
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF585A Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 585A (Z585A_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q6P3V2

UniProtKB/Swiss-Prot:

Z585A_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF585A: view

Function for ZNF585A Gene

Molecular function for ZNF585A Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF585A Gene

Gene Ontology (GO) - Molecular Function for ZNF585A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF585A: view
genes like me logo Genes that share phenotypes with ZNF585A: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF585A Gene

Localization for ZNF585A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF585A Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF585A gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF585A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF585A: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF585A Gene

Pathways & Interactions for ZNF585A Gene

genes like me logo Genes that share pathways with ZNF585A: view

Pathways by source for ZNF585A Gene

2 Reactome pathways for ZNF585A Gene
1 KEGG pathway for ZNF585A Gene

Gene Ontology (GO) - Biological Process for ZNF585A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF585A: view

No data available for SIGNOR curated interactions for ZNF585A Gene

Drugs & Compounds for ZNF585A Gene

No Compound Related Data Available

Transcripts for ZNF585A Gene

mRNA/cDNA for ZNF585A Gene

3 REFSEQ mRNAs :
15 NCBI additional mRNA sequence :
6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF585A Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d ^ 9
SP1: - - - -
SP2: - -
SP3: - - - - - - - - -
SP4: - - - - -
SP5: - - - - -
SP6: - - - -
SP7: - - - -
SP8: - -

Relevant External Links for ZNF585A Gene

GeneLoc Exon Structure for
ZNF585A

Expression for ZNF585A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF585A Gene

Protein differential expression in normal tissues from HIPED for ZNF585A Gene

This gene is overexpressed in Liver, secretome (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF585A Gene



Protein tissue co-expression partners for ZNF585A Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF585A

SOURCE GeneReport for Unigene cluster for ZNF585A Gene:

Hs.659236

Evidence on tissue expression from TISSUES for ZNF585A Gene

  • Nervous system(2.4)
genes like me logo Genes that share expression patterns with ZNF585A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF585A Gene

Orthologs for ZNF585A Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF585A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF585A 31 30
  • 99.09 (n)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF585A 30
  • 89.03 (n)
ZNF484 31
  • 46 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp27 17 31 30
  • 81.1 (n)
rat
(Rattus norvegicus)
Mammalia Zfp27 30
  • 79.52 (n)
dog
(Canis familiaris)
Mammalia ZNF585A 30
  • 77.06 (n)
-- 31
  • 45 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 45 (a)
ManyToMany
-- 31
  • 45 (a)
ManyToMany
-- 31
  • 42 (a)
ManyToMany
-- 31
  • 41 (a)
ManyToMany
-- 31
  • 41 (a)
ManyToMany
-- 31
  • 40 (a)
ManyToMany
-- 31
  • 38 (a)
ManyToMany
-- 31
  • 38 (a)
ManyToMany
-- 31
  • 36 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101733764 30
  • 55.78 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 43 (a)
ManyToMany
-- 31
  • 39 (a)
ManyToMany
-- 31
  • 37 (a)
ManyToMany
-- 31
  • 35 (a)
ManyToMany
-- 31
  • 33 (a)
ManyToMany
CSA.1668 31
  • 32 (a)
ManyToMany
Species where no ortholog for ZNF585A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF585A Gene

ENSEMBL:
Gene Tree for ZNF585A (if available)
TreeFam:
Gene Tree for ZNF585A (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF585A: view image

Paralogs for ZNF585A Gene

Paralogs for ZNF585A Gene

(538) SIMAP similar genes for ZNF585A Gene using alignment to 5 proteins:

  • Z585A_HUMAN
  • C9JK40_HUMAN
  • K7ELR3_HUMAN
  • K7EN80_HUMAN
  • L8EAQ8_HUMAN
genes like me logo Genes that share paralogs with ZNF585A: view

Variants for ZNF585A Gene

Additional dbSNP identifiers (rs#s) for ZNF585A Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF585A Gene

Variant ID Type Subtype PubMed ID
esv3893201 CNV gain 25118596
nsv1064851 CNV loss 25217958
nsv2477 CNV deletion 18451855
nsv579461 CNV gain 21841781
nsv828545 CNV loss 20364138

Variation tolerance for ZNF585A Gene

Residual Variation Intolerance Score: 51.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.86; 67.35% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF585A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF585A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF585A Gene

Disorders for ZNF585A Gene

Additional Disease Information for ZNF585A

No disorders were found for ZNF585A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF585A Gene

Publications for ZNF585A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 54
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 54
  5. Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. (PMID: 20562864) Nozawa RS … Obuse C (Nature cell biology 2010) 3 54

Products for ZNF585A Gene