Aliases for ZNF579 Gene

Aliases for ZNF579 Gene

  • Zinc Finger Protein 579 2 3 4 5

External Ids for ZNF579 Gene

Previous GeneCards Identifiers for ZNF579 Gene

  • GC19M060781
  • GC19M060782
  • GC19M056088
  • GC19M052399

Summaries for ZNF579 Gene

GeneCards Summary for ZNF579 Gene

ZNF579 (Zinc Finger Protein 579) is a Protein Coding gene. An important paralog of this gene is ZNF850.

UniProtKB/Swiss-Prot Summary for ZNF579 Gene

Additional gene information for ZNF579 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF579 Gene

Genomics for ZNF579 Gene

GeneHancer (GH) Regulatory Elements for ZNF579 Gene

Promoters and enhancers for ZNF579 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF579 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF579

Top Transcription factor binding sites by QIAGEN in the ZNF579 gene promoter:
  • AP-4
  • ATF6
  • E2F
  • E2F-1
  • MAZR
  • Olf-1
  • p53
  • Pax-6
  • Spz1

Genomic Locations for ZNF579 Gene

Genomic Locations for ZNF579 Gene
4,126 bases
Minus strand
3,321 bases
Minus strand

Genomic View for ZNF579 Gene

Genes around ZNF579 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF579 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF579 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF579 Gene

Proteins for ZNF579 Gene

  • Protein details for ZNF579 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 579
    Protein Accession:

    Protein attributes for ZNF579 Gene

    562 amino acids
    Molecular mass:
    60509 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF579 Gene

Post-translational modifications for ZNF579 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF579 Gene

No data available for DME Specific Peptides for ZNF579 Gene

Domains & Families for ZNF579 Gene

Gene Families for ZNF579 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF579 Gene


Suggested Antigen Peptide Sequences for ZNF579 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 579 (ZN579_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF579: view

Function for ZNF579 Gene

Molecular function for ZNF579 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF579 Gene

Gene Ontology (GO) - Molecular Function for ZNF579 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003723 RNA binding HDA 22681889
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF579: view
genes like me logo Genes that share phenotypes with ZNF579: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF579 Gene

Localization for ZNF579 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF579 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF579 gene
Compartment Confidence
nucleus 4
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF579 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF579: view

Pathways & Interactions for ZNF579 Gene

PathCards logo

SuperPathways for ZNF579 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF579 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZNF579 Gene

Drugs & Compounds for ZNF579 Gene

No Compound Related Data Available

Transcripts for ZNF579 Gene

mRNA/cDNA for ZNF579 Gene

5 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF579 Gene

No ASD Table

Relevant External Links for ZNF579 Gene

GeneLoc Exon Structure for

Expression for ZNF579 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF579 Gene

Protein differential expression in normal tissues from HIPED for ZNF579 Gene

This gene is overexpressed in Bone marrow stromal cell (20.9), Fetal Brain (17.9), and Adrenal (14.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF579 Gene

Protein tissue co-expression partners for ZNF579 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF579

SOURCE GeneReport for Unigene cluster for ZNF579 Gene:


Evidence on tissue expression from TISSUES for ZNF579 Gene

  • Intestine(4.1)
genes like me logo Genes that share expression patterns with ZNF579: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF579 Gene

Orthologs for ZNF579 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF579 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF579 31 30
  • 99.55 (n)
(Canis familiaris)
Mammalia ZNF579 31 30
  • 85.4 (n)
(Bos Taurus)
Mammalia ZNF579 30
  • 83.76 (n)
(Mus musculus)
Mammalia Zfp579 17 31 30
  • 80.87 (n)
(Rattus norvegicus)
Mammalia Zfp579 30
  • 80.61 (n)
Species where no ortholog for ZNF579 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF579 Gene

Gene Tree for ZNF579 (if available)
Gene Tree for ZNF579 (if available)
Evolutionary constrained regions (ECRs) for ZNF579: view image

Paralogs for ZNF579 Gene

Paralogs for ZNF579 Gene

(11) SIMAP similar genes for ZNF579 Gene using alignment to 2 proteins:

  • ZN579_HUMAN
genes like me logo Genes that share paralogs with ZNF579: view

Variants for ZNF579 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF579 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs10403008 - p.Glu353Asp

Additional dbSNP identifiers (rs#s) for ZNF579 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF579 Gene

Variant ID Type Subtype PubMed ID
nsv828643 CNV loss 20364138
nsv953624 CNV deletion 24416366

Variation tolerance for ZNF579 Gene

Gene Damage Index Score: 2.60; 45.08% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF579 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF579 Gene

Disorders for ZNF579 Gene

Additional Disease Information for ZNF579

No disorders were found for ZNF579 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF579 Gene

Publications for ZNF579 Gene

No publications were found for ZNF579 Gene.

Products for ZNF579 Gene

Sources for ZNF579 Gene