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Aliases for ZNF571 Gene

Aliases for ZNF571 Gene

  • Zinc Finger Protein 571 2 3 5
  • HSPC059 3

External Ids for ZNF571 Gene

Previous GeneCards Identifiers for ZNF571 Gene

  • GC19M042745
  • GC19M038053
  • GC19M034505
  • GC19M037578
  • GC19M037580
  • GC19M037584
  • GC19M037657
  • GC19M037759
  • GC19M037771
  • GC19M038060

Summaries for ZNF571 Gene

GeneCards Summary for ZNF571 Gene

ZNF571 (Zinc Finger Protein 571) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and structural molecule activity. An important paralog of this gene is ZNF790.

UniProtKB/Swiss-Prot for ZNF571 Gene

  • May be involved in transcriptional regulation.

Gene Wiki entry for ZNF571 Gene

Additional gene information for ZNF571 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF571 Gene

Genomics for ZNF571 Gene

GeneHancer (GH) Regulatory Elements for ZNF571 Gene

Promoters and enhancers for ZNF571 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I037593 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 723.6 +0.1 91 2.2 PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 IRF4 YY1 SLC30A9 ZNF213 ZNF571 ZNF540 ZNF567 ZNF527 ZFP30 ZNF383 HKR1 ZNF345 ZNF585A ZNF607
GH19I037653 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 179.9 -60.5 -60508 3 MLX ZFP64 FEZF1 DMAP1 YY1 ZNF213 ZNF416 ZNF143 ZNF548 SP3 ZFP30 ZNF527 ZNF567 ZNF383 ZNF345 ZNF571 ZNF790 HKR1 ZNF850 ZNF585A
GH19I037370 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 175.1 +223.8 223752 1.9 HDGF PKNOX1 SMAD1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 ZNF213 ZNF527 ZNF567 ZNF383 ZNF345 ZFP30 ZNF571 HKR1 ZNF850 ZNF793 ZNF790
GH19I037466 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 172 +126.6 126577 4.4 FEZF1 DMAP1 IRF4 YY1 ZNF213 ZNF416 ZNF143 ZNF548 SP3 ZC3H11A ZNF570 ZNF569 ZNF567 ZNF345 ZNF383 ZNF527 ZNF850 ZNF571 ZNF585B HKR1
GH19I036915 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE 123.6 +678.3 678297 2.2 PKNOX1 ARID4B SIN3A ZNF2 YY1 ZNF302 ZNF416 ZNF143 ZNF548 SP3 ZNF568 ZNF829 GC19M038851 ZNF527 ZNF567 ZNF345 ZNF383 ZFP30 ZNF571 ZNF850
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF571 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF571 gene promoter:

Genomic Locations for ZNF571 Gene

Genomic Locations for ZNF571 Gene
chr19:37,554,782-37,594,792
(GRCh38/hg38)
Size:
40,011 bases
Orientation:
Minus strand
chr19:38,045,684-38,085,673
(GRCh37/hg19)

Genomic View for ZNF571 Gene

Genes around ZNF571 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF571 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF571 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF571 Gene

Proteins for ZNF571 Gene

  • Protein details for ZNF571 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z3V5-ZN571_HUMAN
    Recommended name:
    Zinc finger protein 571
    Protein Accession:
    Q7Z3V5
    Secondary Accessions:
    • Q2HIY0
    • Q3ZCU3
    • Q9NZX7

    Protein attributes for ZNF571 Gene

    Size:
    609 amino acids
    Molecular mass:
    70792 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF571 Gene

Post-translational modifications for ZNF571 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF571 Gene

Domains & Families for ZNF571 Gene

Gene Families for ZNF571 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF571 Gene

Suggested Antigen Peptide Sequences for ZNF571 Gene

Graphical View of Domain Structure for InterPro Entry

Q7Z3V5

UniProtKB/Swiss-Prot:

ZN571_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF571: view

Function for ZNF571 Gene

Molecular function for ZNF571 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF571 Gene

Gene Ontology (GO) - Molecular Function for ZNF571 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0005198 structural molecule activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF571: view
genes like me logo Genes that share phenotypes with ZNF571: view

miRNA for ZNF571 Gene

miRTarBase miRNAs that target ZNF571

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF571 Gene

Localization for ZNF571 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF571 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF571 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoli (2)
  • Nucleus (2)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF571 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IDA --
GO:0019028 viral capsid IEA --
genes like me logo Genes that share ontologies with ZNF571: view

Pathways & Interactions for ZNF571 Gene

SuperPathways for ZNF571 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF571: view

Pathways by source for ZNF571 Gene

2 Reactome pathways for ZNF571 Gene

Interacting Proteins for ZNF571 Gene

Gene Ontology (GO) - Biological Process for ZNF571 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
GO:0019058 viral life cycle IEA --
genes like me logo Genes that share ontologies with ZNF571: view

No data available for SIGNOR curated interactions for ZNF571 Gene

Drugs & Compounds for ZNF571 Gene

No Compound Related Data Available

Transcripts for ZNF571 Gene

Unigene Clusters for ZNF571 Gene

Zinc finger protein 571:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF571 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c
SP1: - -
SP2:
SP3: -

Relevant External Links for ZNF571 Gene

GeneLoc Exon Structure for
ZNF571
ECgene alternative splicing isoforms for
ZNF571

Expression for ZNF571 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF571 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF571 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF571 Gene



Protein tissue co-expression partners for ZNF571 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF571 Gene:

ZNF571

SOURCE GeneReport for Unigene cluster for ZNF571 Gene:

Hs.590944

Evidence on tissue expression from TISSUES for ZNF571 Gene

  • Blood(4.1)
  • Eye(4.1)
genes like me logo Genes that share expression patterns with ZNF571: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF571 Gene

Orthologs for ZNF571 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF571 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF571 33 34
  • 99.29 (n)
dog
(Canis familiaris)
Mammalia ZNF571 34
  • 81 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF383 34
  • 50 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 49 (a)
OneToMany
Species where no ortholog for ZNF571 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF571 Gene

ENSEMBL:
Gene Tree for ZNF571 (if available)
TreeFam:
Gene Tree for ZNF571 (if available)

Paralogs for ZNF571 Gene

(507) SIMAP similar genes for ZNF571 Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for ZNF571 Gene

genes like me logo Genes that share paralogs with ZNF571: view

Variants for ZNF571 Gene

Sequence variations from dbSNP and Humsavar for ZNF571 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000105307 -- 37,567,646(-) G/T intron_variant
rs1000136509 -- 37,567,366(-) C/T intron_variant
rs1000367235 -- 37,588,246(-) T/A intron_variant
rs1000381410 -- 37,581,350(-) C/T intron_variant
rs1000412419 -- 37,580,952(-) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF571 Gene

Variant ID Type Subtype PubMed ID
esv3355793 CNV insertion 20981092
nsv1134790 CNV deletion 24896259
nsv474205 CNV novel sequence insertion 20440878
nsv579468 CNV gain 21841781

Variation tolerance for ZNF571 Gene

Residual Variation Intolerance Score: 92.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 17.18; 98.09% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF571 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF571

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF571 Gene

Disorders for ZNF571 Gene

Additional Disease Information for ZNF571

No disorders were found for ZNF571 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF571 Gene

Publications for ZNF571 Gene

  1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang QH … Chen Z (Genome research 2000) 2 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 58
  5. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A … Wiemann S (Nucleic acids research 2006) 3 58

Products for ZNF571 Gene

Sources for ZNF571 Gene

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